| American Friends of Kupat Ha'irEIN 20-1523797 | Human Services | NY | $6,536,406Mid-sized | 73.90 |
| American Friends of Meir PanimEIN 20-1582478 | Human Services | NY | $5,126,089Mid-sized | 92.41 |
| American Friends of Migdal OhrEIN 13-3389558 | Human Services | NY | $5,992,863Mid-sized | 94.44 |
| American Friends of Shalva IsraelEIN 56-2676533 | Human Services | NY | $4,298,752Mid-sized | 87.30 |
| American Friends of Yad EliezerEIN 11-3459952 | Human Services | NJ | $41,944,264Large | 94.69 |
| American Indian Science and Engineering SocietyEIN 73-1023474 | Human Services | NM | $4,132,365Mid-sized | 86.99 |
| American Printing House For The BlindEIN 61-0444640 | Human Services | KY | $18,252,464Large | 84.71 |
| American Red CrossEIN 53-0196605 | Human Services | DC | $3,142,984,060Large | 88.71 |
| American Youth FoundationEIN 43-0652614 | Human Services | MO | $6,196,477Mid-sized | 92.39 |
| Amherst H. Wilder FoundationEIN 41-0693889 | Human Services | MN | $45,788,233Large | 86.30 |
| Amigos de JesusEIN 23-3027589 | Human Services | PA | $1,391,900Small | 83.73 |
| Amigos For KidsEIN 65-0361629 | Human Services | FL | $1,912,759Small | 91.36 |
| Anchor Center for Blind ChildrenEIN 84-0893509 | Human Services | CO | $2,124,573Small | 87.46 |
| Andy Roddick FoundationEIN 20-0014500 | Human Services | TX | $1,928,371Small | 83.73 |
| Anne Arundel County Food BankEIN 52-1660473 | Human Services | MD | $3,890,270Mid-sized | 78.71 |
| Arby's FoundationEIN 58-1692997 | Human Services | GA | $8,124,464Mid-sized | 94.58 |
| Arizona Women's Education and EmploymentEIN 86-0412509 | Human Services | AZ | $2,252,823Small | 73.68 |
| Arkansas Baptist Children's Homes and Family MinistriesEIN 71-0296619 | Human Services | AR | $4,388,581Mid-sized | 86.51 |
| Arkansas FoodbankEIN 71-0596734 | Human Services | AR | $43,348,876Large | 90.22 |
| Arkansas Sheriffs' Youth RanchesEIN 71-0471266 | Human Services | AR | $2,273,259Small | 83.59 |
| Arlington Food Assistance CenterEIN 54-1473207 | Human Services | VA | $5,583,702Mid-sized | 96.40 |
| Arlington Street People's Assistance NetworkEIN 54-1615993 | Human Services | VA | $4,004,806Mid-sized | 90.58 |
| Arm In ArmEIN 22-3198464 | Human Services | NJ | $2,461,297Small | 95.29 |
| Armed Services YMCAEIN 36-3274346 | Human Services | VA | $22,350,334Large | 93.12 |
| Arms of HopeEIN 75-0904045 | Human Services | TX | $9,318,892Mid-sized | 87.35 |
| Army Emergency ReliefEIN 53-0196552 | Human Services | VA | $28,198,705Large | 93.98 |
| Assistance League of AustinEIN 23-7307276 | Human Services | TX | $1,215,984Small | 96.46 |
| Associated Services for the Blind and Visually ImpairedEIN 23-1370508 | Human Services | PA | $3,718,143Mid-sized | 78.35 |
| Association of Gospel Rescue Missions dba Citygate NetworkEIN 55-0479715 | Human Services | CO | $2,050,377Small | 90.53 |
| Association on American Indian AffairsEIN 13-1623902 | Human Services | MD | $488,251Small | 77.23 |
| Association to Benefit ChildrenEIN 13-3303089 | Human Services | NY | $18,345,443Large | 96.61 |
| Athol Area YMCAEIN 04-2103727 | Human Services | MA | $1,310,042Small | 81.56 |
| Atlanta Children's ShelterEIN 58-1675299 | Human Services | GA | $1,313,147Small | 84.73 |
| Atlanta Community Food BankEIN 58-1376648 | Human Services | GA | $144,693,855Large | 90.58 |
| Atlanta MissionEIN 58-0572430 | Human Services | GA | $17,707,982Large | 85.25 |
| Atlanta Police FoundationEIN 11-3655936 | Human Services | GA | $8,487,172Mid-sized | 91.51 |
| Atlantic City Rescue MissionEIN 22-6076337 | Human Services | NJ | $3,201,818Small | 71.26 |
| Attention HomesEIN 84-0571145 | Human Services | CO | $1,918,605Small | 84.84 |
| Austin YMBL Sunshine CampsEIN 74-6023176 | Human Services | TX | $1,174,474Small | 92.18 |
| AvenidasEIN 94-1480548 | Human Services | CA | $4,848,199Mid-sized | 88.32 |
| Avenues for Homeless YouthEIN 41-1765140 | Human Services | MN | $2,332,809Small | 91.12 |
| Avenues for JusticeEIN 13-3267496 | Human Services | NY | $1,525,572Small | 94.68 |
| Back on My FeetEIN 26-2109809 | Human Services | PA | $6,123,556Mid-sized | 80.51 |
| Ballard Food BankEIN 91-1428805 | Human Services | WA | $3,535,111Mid-sized | 91.16 |
| Baptist Children's Homes of North CarolinaEIN 56-0547499 | Human Services | NC | $25,600,894Large | 96.21 |
| Barnabas CenterEIN 59-2920275 | Human Services | FL | $3,364,655Small | 98.23 |
| Bay Area Rescue MissionEIN 94-6124054 | Human Services | CA | $9,971,930Mid-sized | 80.28 |
| Bayith LepleitotEIN 11-2213686 | Human Services | NY | $3,965,586Mid-sized | 61.20 |
| Bean's CafeEIN 92-0072522 | Human Services | AK | $2,577,325Small | 87.89 |
| Bender Jewish Community Center of Greater WashingtonEIN 53-0205921 | Human Services | MD | $14,681,556Large | 92.74 |
| BenevillaEIN 86-0404687 | Human Services | AZ | $6,396,221Mid-sized | 89.35 |
| Benjamin Rose Institute on AgingEIN 34-0714482 | Human Services | OH | $11,049,876Mid-sized | 80.90 |
| Best Buddies InternationalEIN 52-1614576 | Human Services | FL | $26,289,255Large | 87.85 |
| Bethel Bible VillageEIN 62-6019872 | Human Services | TN | $2,186,364Small | 92.20 |
| Bethesda Lutheran CommunitiesEIN 39-0806446 | Human Services | WI | $150,208,423Large | 84.39 |
| Bethesda MissionEIN 23-1389397 | Human Services | PA | $7,449,308Mid-sized | 90.71 |
| Bethesda-Chevy Chase Rescue SquadEIN 52-0583872 | Human Services | MD | $1,992,723Small | 90.71 |
| Beverly BootstrapEIN 04-3254507 | Human Services | MA | $2,781,956Small | 88.49 |
| Big Brothers Big Sisters A Community of CaringEIN 38-1720832 | Human Services | MI | $1,294,439Small | 86.88 |
| Big Brothers Big Sisters Columbia NorthwestEIN 93-1303640 | Human Services | OR | $1,080,910Small | 67.12 |