| AAA Foundation for Traffic SafetyEIN 52-0794368 | Research and Public Policy | DC | $7,776,718Mid-sized | 92.02 |
| ABC² (Accelerate Brain Cancer Cure)EIN 52-2320756 | Health | DC | $2,236,166Small | 79.97 |
| Academy of AchievementEIN 75-6042129 | Education | DC | $2,047,357Small | 83.43 |
| Academy of Hope Adult Public Charter SchoolEIN 52-1730021 | Education | DC | $5,648,649Mid-sized | 84.67 |
| Action on Smoking and HealthEIN 13-2603590 | Health | DC | $1,296,503Small | 90.77 |
| ActionAid USAEIN 52-2277575 | International | DC | $8,143,431Mid-sized | 92.44 |
| Advocates for YouthEIN 52-1173590 | Health | DC | $7,801,341Mid-sized | 94.00 |
| AfricareEIN 23-7116952 | International | DC | $26,832,661Large | 78.62 |
| Afterschool AllianceEIN 52-2275123 | Education | DC | $5,555,130Mid-sized | 91.45 |
| Aga Khan Foundation, USAEIN 52-1231983 | International | DC | $47,638,836Large | 86.72 |
| AIDS UnitedEIN 52-1706646 | Health | DC | $10,649,510Mid-sized | 90.91 |
| Alexander Graham Bell Association for the Deaf and Hard of HearingEIN 53-0196644 | Health | DC | $3,417,603Small | 81.88 |
| Alliance for Aging ResearchEIN 54-1379174 | Research and Public Policy | DC | $1,867,638Small | 89.69 |
| Alliance for JusticeEIN 52-1009973 | Human and Civil Rights | DC | $5,029,169Mid-sized | 95.83 |
| Alliance to Save EnergyEIN 52-1082991 | Environment | DC | $4,083,682Mid-sized | 70.28 |
| Amazon Conservation AssociationEIN 52-2211305 | Environment | DC | $5,038,940Mid-sized | 93.33 |
| America's Promise AllianceEIN 54-1848713 | Human Services | DC | $11,854,378Mid-sized | 84.10 |
| American Architectural FoundationEIN 52-0847434 | Community Development | DC | $2,788,730Small | 78.80 |
| American Association for the Advancement of ScienceEIN 53-0196568 | Research and Public Policy | DC | $107,624,973Large | 87.49 |
| American Association of People with DisabilitiesEIN 52-1930174 | Human and Civil Rights | DC | $1,360,471Small | 81.67 |
| American Battlefield TrustEIN 54-1426643 | Arts, Culture, Humanities | DC | $17,884,556Large | 96.94 |
| American Constitution Society for Law and PolicyEIN 52-2313694 | Research and Public Policy | DC | $5,891,120Mid-sized | 88.13 |
| American Council for an Energy-Efficient Economy EIN 94-2711707 | Research and Public Policy | DC | $9,400,072Mid-sized | 95.43 |
| American Enterprise Institute for Public Policy ResearchEIN 53-0218495 | Research and Public Policy | DC | $55,822,303Large | 87.22 |
| American Federation for Children Growth FundEIN 52-2111508 | Education | DC | $7,828,481Mid-sized | 83.70 |
| American Forest FoundationEIN 52-1235124 | Environment | DC | $13,062,939Mid-sized | 96.39 |
| American ForestsEIN 53-0196544 | Environment | DC | $5,495,270Mid-sized | 86.81 |
| American Friends of LubavitchEIN 52-2193738 | Religion | DC | $1,448,713Small | 44.41 |
| American HumaneEIN 84-0432950 | Animals | DC | $15,536,919Large | 90.25 |
| American Humanist AssociationEIN 94-6168317 | Human and Civil Rights | DC | $2,295,879Small | 93.41 |
| American Immigration CouncilEIN 52-1549711 | Human and Civil Rights | DC | $5,483,109Mid-sized | 94.52 |
| American Institute for Contemporary German StudiesEIN 52-1309525 | International | DC | $1,959,488Small | 86.76 |
| American Israel Education FoundationEIN 52-1623781 | Education | DC | $56,112,739Large | 81.71 |
| American Psychiatric Association FoundationEIN 13-0433740 | Health | DC | $5,462,166Mid-sized | 86.81 |
| American Red CrossEIN 53-0196605 | Human Services | DC | $3,142,984,060Large | 88.71 |
| American RiversEIN 23-7305963 | Environment | DC | $14,465,768Large | 86.37 |
| American Youth Policy ForumEIN 31-1576455 | Research and Public Policy | DC | $1,439,978Small | 91.69 |
| Americans for Peace NowEIN 13-3509867 | International | DC | $1,602,208Small | 82.25 |
| Americans for the ArtsEIN 52-1996467 | Arts, Culture, Humanities | DC | $16,084,664Large | 91.45 |
| Americans United for Separation of Church and StateEIN 53-0184647 | Human and Civil Rights | DC | $7,210,878Mid-sized | 81.63 |
| AneraEIN 52-0882226 | International | DC | $68,483,582Large | 92.56 |
| Animal Welfare InstituteEIN 13-5655952 | Animals | DC | $2,737,309Small | 92.92 |
| APhA FoundationEIN 52-6039142 | Research and Public Policy | DC | $1,640,653Small | 73.17 |
| AppleseedEIN 52-1835698 | Human and Civil Rights | DC | $1,074,765Small | 77.73 |
| Armenian Assembly of AmericaEIN 52-1614093 | International | DC | $3,569,175Mid-sized | 90.04 |
| Asian & Pacific Islander American Scholarship FundEIN 57-1192973 | Education | DC | $20,152,919Large | 89.92 |
| Asian Americans Advancing JusticeEIN 13-3619000 | Human and Civil Rights | DC | $3,121,510Small | 86.67 |
| Association for Enterprise OpportunityEIN 36-3834357 | Community Development | DC | $2,163,035Small | 92.20 |
| Association of Performing Arts ProfessionalsEIN 39-1131995 | Arts, Culture, Humanities | DC | $5,793,329Mid-sized | 93.91 |
| Association of Reproductive Health ProfessionalsEIN 52-1591381 | Health | DC | $1,538,776Small | 85.38 |
| AyudaEIN 52-0971440 | Human and Civil Rights | DC | $3,726,155Mid-sized | 93.98 |
| B'nai B'rith InternationalEIN 53-0179971 | International | DC | $7,934,468Mid-sized | 65.38 |
| BBYOEIN 31-1794932 | Religion | DC | $31,255,555Large | 85.97 |
| Better World FundEIN 58-2366765 | International | DC | $5,346,277Mid-sized | 78.51 |
| Beyond BordersEIN 23-2713126 | International | DC | $1,960,030Small | 92.90 |
| Beyond PesticidesEIN 52-1360541 | Environment | DC | $1,025,719Small | 90.35 |
| Black Student FundEIN 52-6053597 | Education | DC | $407,911Small | 64.72 |
| Boys & Girls Clubs of Greater WashingtonEIN 53-0236759 | Human Services | DC | $11,258,246Mid-sized | 72.39 |
| BradyEIN 52-1285097 | Human and Civil Rights | DC | $4,329,018Mid-sized | 70.11 |
| Bread for the CityEIN 52-1138207 | Human Services | DC | $12,783,659Mid-sized | 92.61 |