| Congressional Sportsmen's FoundationEIN 52-1686163 | Animals | DC | $4,450,193Mid-sized | 78.44 |
| Conservation Strategy FundEIN 94-3294843 | Environment | DC | $2,079,533Small | 87.92 |
| Constitutional Accountability CenterEIN 52-2063854 | Research and Public Policy | DC | $3,469,685Small | 91.86 |
| Council for a Strong AmericaEIN 13-3840271 | Research and Public Policy | DC | $11,660,559Mid-sized | 95.16 |
| Council for National PolicyEIN 72-0921017 | Research and Public Policy | DC | $2,680,790Small | 84.02 |
| Council of Independent CollegesEIN 01-6004776 | Education | DC | $13,706,554Large | 87.42 |
| Covenant House WashingtonEIN 13-3537709 | Human Services | DC | $5,553,135Mid-sized | 90.93 |
| Cultural Landscape FoundationEIN 52-2092229 | Environment | DC | $1,301,543Small | 86.63 |
| D.C. Bar Pro Bono CenterEIN 52-1574217 | Human and Civil Rights | DC | $2,824,873Small | 93.74 |
| D.C. Central KitchenEIN 52-1584936 | Human Services | DC | $16,677,394Large | 92.92 |
| Dance/USAEIN 52-1253457 | Arts, Culture, Humanities | DC | $2,307,036Small | 87.61 |
| Daughters of the American RevolutionEIN 53-0205923 | Arts, Culture, Humanities | DC | $16,267,791Large | 75.61 |
| DEA Educational FoundationEIN 52-1922097 | Health | DC | $1,197,681Small | 81.54 |
| District of Columbia College Access ProgramEIN 52-2132835 | Education | DC | $7,157,083Mid-sized | 86.80 |
| DKT InternationalEIN 58-1593137 | International | DC | $199,519,332Large | 88.81 |
| Earth Conservation CorpsEIN 52-1683270 | Environment | DC | $350,700Small | 74.09 |
| Earth Day NetworkEIN 13-3798288 | Environment | DC | $2,970,282Small | 91.94 |
| EarthEcho InternationalEIN 95-4789334 | Environment | DC | $698,764Small | 82.66 |
| EarthRights InternationalEIN 04-3265555 | International | DC | $3,343,499Small | 99.01 |
| EARTHWORKSEIN 52-1557765 | Environment | DC | $3,301,953Small | 94.74 |
| ecoAmericaEIN 20-3895611 | Environment | DC | $4,482,513Mid-sized | 88.77 |
| Economic Policy InstituteEIN 52-1368964 | Research and Public Policy | DC | $6,502,386Mid-sized | 90.38 |
| Educando by WorldfundEIN 03-0483824 | International | DC | $2,874,579Small | 94.18 |
| Education For EmploymentEIN 82-0578781 | Education | DC | $5,167,691Mid-sized | 90.31 |
| Education Writers AssociationEIN 23-7439790 | Education | DC | $2,594,778Small | 90.26 |
| Electronic Privacy Information CenterEIN 52-2225921 | Human and Civil Rights | DC | $1,523,199Small | 97.17 |
| Elizabeth Glaser Pediatric AIDS FoundationEIN 95-4191698 | Health | DC | $180,014,269Large | 88.29 |
| EngenderHealthEIN 13-1623838 | International | DC | $61,909,568Large | 88.50 |
| Environmental and Energy Study InstituteEIN 52-1268030 | Environment | DC | $1,296,571Small | 100.00 |
| Environmental Integrity ProjectEIN 20-1326922 | Environment | DC | $3,168,637Small | 84.42 |
| Environmental Investigation AgencyEIN 52-1654284 | Environment | DC | $4,791,938Mid-sized | 89.39 |
| Environmental Law InstituteEIN 52-0901863 | Environment | DC | $5,604,514Mid-sized | 92.44 |
| Environmental Working GroupEIN 52-2148600 | Environment | DC | $9,318,340Mid-sized | 91.51 |
| Equal Justice WorksEIN 52-1469738 | Human and Civil Rights | DC | $17,605,902Large | 90.17 |
| Ethics and Public Policy CenterEIN 52-1162185 | Research and Public Policy | DC | $3,827,567Mid-sized | 89.98 |
| Every Voice CenterEIN 52-2003442 | Human and Civil Rights | DC | $2,340,028Small | 83.86 |
| Excelencia in EducationEIN 20-0927912 | Education | DC | $2,020,426Small | 87.62 |
| Fabretto Children's FoundationEIN 36-3894824 | Education | DC | $4,686,337Mid-sized | 86.21 |
| Fair ChanceEIN 74-3091832 | Human Services | DC | $1,419,815Small | 86.50 |
| Faith and ActionEIN 22-2443279 | Religion | DC | $1,962,513Small | 65.29 |
| Faith and Politics InstituteEIN 52-1759052 | Education | DC | $1,906,591Small | 73.28 |
| Families Against Mandatory Minimums FoundationEIN 52-1750246 | Human and Civil Rights | DC | $2,314,120Small | 97.13 |
| Families USA FoundationEIN 04-2730934 | Research and Public Policy | DC | $8,981,636Mid-sized | 82.60 |
| Family Online Safety InstituteEIN 52-2210323 | Research and Public Policy | DC | $1,588,755Small | 75.34 |
| FCNL Education FundEIN 52-1254489 | Human and Civil Rights | DC | $3,680,702Mid-sized | 78.94 |
| Federation of American ScientistsEIN 23-7185827 | International | DC | $1,441,697Small | 90.28 |
| First BookEIN 52-1779606 | Education | DC | $106,297,627Large | 88.93 |
| Fonkoze USAEIN 52-2022113 | International | DC | $1,800,783Small | 77.87 |
| Food & FriendsEIN 52-1648941 | Human Services | DC | $8,557,893Mid-sized | 88.01 |
| Food Research & Action CenterEIN 23-7200739 | Research and Public Policy | DC | $11,894,182Mid-sized | 86.79 |
| For Love of ChildrenEIN 52-6064548 | Human Services | DC | $1,826,443Small | 81.96 |
| Ford's Theatre SocietyEIN 52-6073157 | Arts, Culture, Humanities | DC | $15,488,061Large | 94.49 |
| Forest TrendsEIN 52-2135531 | Environment | DC | $10,556,855Mid-sized | 86.54 |
| Foundation for Defense of DemocraciesEIN 13-4174402 | Research and Public Policy | DC | $11,705,479Mid-sized | 89.22 |
| Foundation for Financial PlanningEIN 58-1446336 | Community Development | DC | $1,517,085Small | 93.78 |
| Franciscan Foundation for the Holy LandEIN 33-0628775 | Religion | DC | $2,478,438Small | 96.28 |
| Free the SlavesEIN 56-2189635 | International | DC | $3,086,993Small | 82.07 |
| Friends of Cancer ResearchEIN 52-1983273 | Health | DC | $3,503,121Mid-sized | 77.93 |
| Friends of the EarthEIN 23-7420660 | Environment | DC | $10,291,770Mid-sized | 94.64 |
| Friends of the Global Fight Against AIDS, Tuberculosis, and MalariaEIN 30-0220874 | International | DC | $1,751,040Small | 74.78 |