| Catholic Charities of Northeast KansasEIN 48-1181305 | Human Services | KS | $25,350,672Large | 91.16 |
| Catholic Charities of Northern NevadaEIN 88-0339754 | Human Services | NV | $13,099,433Mid-sized | 91.45 |
| Catholic Charities of Santa Clara CountyEIN 94-2762269 | Human Services | CA | $35,534,021Large | 87.91 |
| Catholic Charities of Southern MinnesotaEIN 41-0721636 | Human Services | MN | $2,840,617Small | 93.42 |
| Catholic Charities of SpokaneEIN 91-0569880 | Human Services | WA | $16,225,818Large | 90.52 |
| Catholic Charities of St. Paul and MinneapolisEIN 41-1302487 | Human Services | MN | $50,683,237Large | 92.01 |
| Catholic Charities of the Archdiocese of Galveston-HoustonEIN 74-1109733 | Human Services | TX | $38,475,867Large | 93.20 |
| Catholic Charities of the Archdiocese of MilwaukeeEIN 39-0806321 | Human Services | WI | $6,103,750Mid-sized | 90.64 |
| Catholic Charities of the Archdiocese of Oklahoma CityEIN 73-0636561 | Human Services | OK | $8,014,721Mid-sized | 90.76 |
| Catholic Charities of the Archdiocese of OmahaEIN 47-0376612 | Human Services | NE | $5,110,419Mid-sized | 86.53 |
| Catholic Charities of the Diocese of FresnoEIN 94-1678938 | Human Services | CA | $5,994,629Mid-sized | 91.18 |
| Catholic Charities of the Diocese of Santa RosaEIN 94-2479393 | Human Services | CA | $13,533,849Large | 90.17 |
| Catholic Charities of the East BayEIN 94-2677202 | Human Services | CA | $6,682,589Mid-sized | 79.64 |
| Catholic Charities Southwestern OhioEIN 31-0536968 | Human Services | OH | $16,836,807Large | 87.22 |
| Catholic Charities, Archdiocese of DenverEIN 84-0686679 | Human Services | CO | $25,590,589Large | 95.04 |
| Catholic Charities, Archdiocese of St. LouisEIN 43-0653270 | Human Services | MO | $7,104,722Mid-sized | 95.47 |
| Catholic Charities, Diocese of NorwichEIN 06-0646609 | Human Services | CT | $2,105,175Small | 80.10 |
| Catholic Charities, Diocese of Venice, Inc.EIN 59-2473176 | Human Services | FL | $7,936,897Mid-sized | 90.71 |
| Catholic Community FoundationEIN 34-1908579 | Human Services | OH | $18,059,323Large | 80.25 |
| Catholic Community Services of Lane CountyEIN 93-0409105 | Human Services | OR | $4,582,187Mid-sized | 92.56 |
| Catholic Social Services of AnchorageEIN 92-0037322 | Human Services | AK | $10,584,775Mid-sized | 93.25 |
| Catholic Social Services of ColumbusEIN 31-4379437 | Human Services | OH | $4,873,241Mid-sized | 96.10 |
| Catholic Social Services of Southern NebraskaEIN 47-0751554 | Human Services | NE | $6,160,111Mid-sized | 86.04 |
| CEAPEIN 41-0990340 | Human Services | MN | $4,193,723Mid-sized | 85.73 |
| CEDARSEIN 47-6024881 | Human Services | NE | $12,918,567Mid-sized | 95.72 |
| Cell Phones For SoldiersEIN 20-1343425 | Human Services | MA | $559,483Small | 66.97 |
| Center for Child & Family ServicesEIN 54-0505893 | Human Services | VA | $1,647,899Small | 89.18 |
| Center for Child ProtectionEIN 74-2562585 | Human Services | TX | $5,770,355Mid-sized | 91.45 |
| Center for Children and FamiliesEIN 73-0933253 | Human Services | OK | $2,145,359Small | 92.65 |
| Center for Development ServicesEIN 57-0988275 | Human Services | SC | $1,406,021Small | 93.01 |
| Center for Economic ProgressEIN 36-3693728 | Human Services | IL | $3,171,304Small | 77.27 |
| Center for Hearing and CommunicationEIN 13-1624127 | Human Services | NY | $5,685,758Mid-sized | 86.20 |
| Center for People in NeedEIN 06-1669552 | Human Services | NE | $8,432,172Mid-sized | 90.64 |
| Center for Safety and ChangeEIN 13-2989233 | Human Services | NY | $3,513,740Mid-sized | 90.09 |
| Center for the HomelessEIN 35-1768544 | Human Services | IN | $3,240,450Small | 85.36 |
| Center for the Study of Social PolicyEIN 52-1254948 | Human Services | DC | $13,048,910Mid-sized | 89.42 |
| Center for Women in TransitionEIN 38-2181204 | Human Services | MI | $2,733,719Small | 90.72 |
| Central California Food BankEIN 77-0320851 | Human Services | CA | $65,008,490Large | 94.67 |
| Central Florida YMCAEIN 59-0624430 | Human Services | FL | $59,588,094Large | 85.96 |
| Central Illinois FoodbankEIN 37-1106465 | Human Services | IL | $18,256,991Large | 92.92 |
| Central Iowa Shelter & ServicesEIN 42-1394212 | Human Services | IA | $2,529,003Small | 90.09 |
| Central Pennsylvania Food BankEIN 23-2202250 | Human Services | PA | $83,599,202Large | 98.23 |
| Central Texas Food BankEIN 74-2217350 | Human Services | TX | $88,983,352Large | 96.46 |
| Central Union MissionEIN 53-0218650 | Human Services | DC | $16,421,755Large | 89.86 |
| CentroEIN 41-1290349 | Human Services | MN | $1,493,898Small | 90.38 |
| Chai LifelineEIN 11-2940331 | Human Services | NY | $19,233,028Large | 86.18 |
| Challenge AspenEIN 84-1315910 | Human Services | CO | $3,320,748Small | 100.00 |
| Challenged Athletes FoundationEIN 33-0739596 | Human Services | CA | $8,869,120Mid-sized | 84.16 |
| Channel Islands YMCAEIN 95-1643379 | Human Services | CA | $18,458,636Large | 90.64 |
| Channel One Regional Food BankEIN 41-1379713 | Human Services | MN | $15,937,633Large | 92.05 |
| Chapman PartnershipEIN 65-0425069 | Human Services | FL | $16,277,068Large | 95.11 |
| Charity CarsEIN 59-3362703 | Human Services | FL | $7,458,283Mid-sized | 94.74 |
| Charity MotorsEIN 38-3251827 | Human Services | MI | $6,804,600Mid-sized | 54.61 |
| Charity NewsiesEIN 31-6401150 | Human Services | OH | $1,919,088Small | 94.28 |
| Charlotte Family HousingEIN 58-1599120 | Human Services | NC | $3,197,515Small | 93.41 |
| Charlotte Rescue MissionEIN 56-0571223 | Human Services | NC | $6,345,655Mid-sized | 87.26 |
| Chattanooga Area Food BankEIN 62-0867645 | Human Services | TN | $28,411,914Large | 93.49 |
| Cherry Street Mission MinistriesEIN 34-1133369 | Human Services | OH | $6,252,648Mid-sized | 83.69 |
| Chicago Coalition for the HomelessEIN 36-3292607 | Human Services | IL | $2,898,914Small | 100.00 |
| Chicago LightsEIN 36-3786331 | Human Services | IL | $2,284,416Small | 90.66 |