| American Friends of Shalva IsraelEIN 56-2676533 | Human Services | NY | $4,298,752Mid-sized | 87.30 |
| American Friends of the Hebrew UniversityEIN 13-1568923 | Education | NY | $60,923,877Large | 87.98 |
| American Friends of the Israel MuseumEIN 23-7182582 | Arts, Culture, Humanities | NY | $17,264,366Large | 85.11 |
| American Friends of the Israel National Museum of ScienceEIN 13-3329462 | Arts, Culture, Humanities | NY | $1,274,004Small | 84.82 |
| American Friends of the Israel Philharmonic OrchestraEIN 23-7183563 | Arts, Culture, Humanities | NY | $6,296,009Mid-sized | 86.19 |
| American Friends of the LouvreEIN 52-2376786 | Arts, Culture, Humanities | NY | $4,755,697Mid-sized | 92.02 |
| American Friends of the Open University of IsraelEIN 13-3091674 | Education | NY | $1,111,082Small | 84.69 |
| American Friends of The Tel Aviv UniversityEIN 13-1996126 | Education | NY | $36,078,234Large | 93.25 |
| American Friends of Yeshivot Bnei AkivaEIN 52-6080692 | Education | NY | $688,740Small | 69.87 |
| American India FoundationEIN 13-4159765 | International | NY | $7,577,120Mid-sized | 91.04 |
| American Italian Cancer FoundationEIN 13-3035711 | Health | NY | $1,688,237Small | 91.63 |
| American Jewish CongressEIN 13-1679610 | International | NY | $544,808Small | 53.76 |
| American Jewish Historical SocietyEIN 13-1764804 | Arts, Culture, Humanities | NY | $2,541,630Small | 71.93 |
| American Jewish Joint Distribution CommitteeEIN 13-1656634 | International | NY | $317,102,196Large | 96.37 |
| American Liver FoundationEIN 36-2883000 | Health | NY | $8,921,259Mid-sized | 87.43 |
| American Museum of Natural HistoryEIN 13-6162659 | Arts, Culture, Humanities | NY | $214,025,292Large | 90.52 |
| American Skin AssociationEIN 13-3401320 | Health | NY | $1,405,914Small | 92.92 |
| American Society for the Prevention of Cruelty to AnimalsEIN 13-1623829 | Animals | NY | $208,434,628Large | 83.75 |
| American Society for the Protection of Nature in IsraelEIN 52-1467954 | Animals | NY | $1,822,784Small | 91.16 |
| American Society for Yad VashemEIN 13-3106768 | Arts, Culture, Humanities | NY | $16,168,788Large | 92.22 |
| American Symphony OrchestraEIN 13-1969375 | Arts, Culture, Humanities | NY | $3,301,829Small | 76.28 |
| American Technion SocietyEIN 13-0434195 | Education | NY | $102,913,014Large | 93.52 |
| American Theatre WingEIN 13-1893906 | Arts, Culture, Humanities | NY | $2,895,023Small | 89.28 |
| American-Scandinavian FoundationEIN 13-1623897 | International | NY | $4,819,474Mid-sized | 91.67 |
| Americas SocietyEIN 13-2569185 | International | NY | $6,259,184Mid-sized | 87.88 |
| AMITEIN 13-5631502 | Education | NY | $10,330,407Mid-sized | 93.35 |
| Amnesty International USAEIN 52-0851555 | International | NY | $39,020,245Large | 89.40 |
| Amref Health AfricaEIN 13-1867411 | International | NY | $5,293,222Mid-sized | 85.36 |
| Animal HavenEIN 11-6101487 | Animals | NY | $1,903,122Small | 77.82 |
| Animal Rescue Fund of the HamptonsEIN 23-7400663 | Animals | NY | $4,545,405Mid-sized | 94.58 |
| Anti-Defamation LeagueEIN 13-1818723 | Human and Civil Rights | NY | $63,917,573Large | 78.65 |
| Apollo Theater FoundationEIN 13-3630066 | Arts, Culture, Humanities | NY | $16,923,763Large | 89.07 |
| Appeal of Conscience FoundationEIN 52-6062870 | International | NY | $2,013,717Small | 86.70 |
| Areivim Philanthropic GroupEIN 20-8024537 | Community Development | NY | $1,236,719Small | 80.54 |
| Armenian General Benevolent UnionEIN 13-5600421 | International | NY | $23,318,407Large | 85.03 |
| Art21EIN 13-3920288 | Arts, Culture, Humanities | NY | $1,637,213Small | 83.37 |
| Arthur Ashe Institute for Urban HealthEIN 11-3185372 | Health | NY | $2,988,538Small | 90.43 |
| Asia SocietyEIN 13-3234632 | International | NY | $31,773,102Large | 85.53 |
| Association to Benefit ChildrenEIN 13-3303089 | Human Services | NY | $18,345,443Large | 96.61 |
| Astraea Lesbian Foundation for JusticeEIN 13-2992977 | Human and Civil Rights | NY | $10,279,723Mid-sized | 93.32 |
| Autism SpeaksEIN 20-2329938 | Health | NY | $42,861,302Large | 80.10 |
| Avenues for JusticeEIN 13-3267496 | Human Services | NY | $1,525,572Small | 94.68 |
| Ballet HispánicoEIN 13-2685755 | Arts, Culture, Humanities | NY | $5,880,403Mid-sized | 92.38 |
| Ballet Tech FoundationEIN 13-2773475 | Arts, Culture, Humanities | NY | $3,421,242Small | 92.52 |
| Bang on a CanEIN 13-3392963 | Arts, Culture, Humanities | NY | $2,167,366Small | 81.29 |
| Bayith LepleitotEIN 11-2213686 | Human Services | NY | $3,965,586Mid-sized | 61.20 |
| Bend the Arc: A Jewish Partnership for JusticeEIN 52-1332694 | Human and Civil Rights | NY | $3,103,664Small | 77.70 |
| Bermuda Institute of Ocean SciencesEIN 06-0706038 | Research and Public Policy | NY | $15,876,165Large | 94.04 |
| BideaweeEIN 13-1655210 | Animals | NY | $10,621,175Mid-sized | 83.88 |
| Big Brothers Big Sisters of New York CityEIN 13-5600383 | Human Services | NY | $10,979,467Mid-sized | 88.90 |
| Birthright Israel FoundationEIN 13-4092050 | Education | NY | $98,592,432Large | 90.74 |
| Bivona Child Advocacy CenterEIN 03-0519569 | Human Services | NY | $1,571,580Small | 94.34 |
| Bnai Zion FoundationEIN 13-2572288 | International | NY | $4,004,928Mid-sized | 95.79 |
| Bonei OlamEIN 11-3473757 | Health | NY | $9,800,311Mid-sized | 85.03 |
| Boy Scouts of America, Greater New York CouncilsEIN 13-1624015 | Human Services | NY | $12,708,411Mid-sized | 86.69 |
| Boy Scouts of America, Greater Niagara Frontier CouncilEIN 16-0743929 | Human Services | NY | $2,221,271Small | 85.73 |
| Boy Scouts of America, Hudson Valley CouncilEIN 14-1338385 | Human Services | NY | $1,537,322Small | 74.80 |
| Boy Scouts of America, Twin Rivers CouncilEIN 14-1340028 | Human Services | NY | $2,131,140Small | 85.89 |
| Boys & Girls Clubs of SyracuseEIN 15-0532240 | Human Services | NY | $1,566,262Small | 84.81 |
| Boys & Girls Harbor, New YorkEIN 13-6015256 | Human Services | NY | $7,935,544Mid-sized | 72.09 |