| Houston Museum of Natural ScienceEIN 74-1036131 | Arts, Culture, Humanities | TX | $35,434,393Large | 88.66 |
| Houston Public Media FoundationEIN 74-1670740 | Arts, Culture, Humanities | TX | $15,686,987Large | 89.28 |
| Houston Volunteer Lawyers ProgramEIN 76-0090652 | Human and Civil Rights | TX | $2,543,934Small | 86.33 |
| Hubbard Street Dance ChicagoEIN 36-2950283 | Arts, Culture, Humanities | IL | $6,060,883Mid-sized | 80.99 |
| Hudson River Sloop ClearwaterEIN 14-6049022 | Environment | NY | $2,470,234Small | 81.25 |
| Human Development Foundation of North AmericaEIN 36-4184940 | International | IL | $2,164,244Small | 83.35 |
| Human Life InternationalEIN 52-1241765 | Human and Civil Rights | VA | $2,755,336Small | 82.32 |
| Human OptionsEIN 95-3667817 | Human Services | CA | $5,329,407Mid-sized | 88.24 |
| Human Race Theatre CompanyEIN 31-1176135 | Arts, Culture, Humanities | OH | $1,749,607Small | 84.83 |
| Human Rights Campaign FoundationEIN 52-1481896 | Human and Civil Rights | DC | $16,850,495Large | 84.29 |
| Human Rights FirstEIN 13-3116646 | International | NY | $11,510,302Mid-sized | 80.00 |
| Human Rights InitiativeEIN 75-2842602 | International | TX | $3,917,851Mid-sized | 88.30 |
| Human Rights WatchEIN 13-2875808 | International | NY | $70,558,186Large | 85.82 |
| Humane America Animal FoundationEIN 95-4761276 | Animals | CA | $4,024,885Mid-sized | 88.96 |
| Humane Animal RescueEIN 25-0325750 | Animals | PA | $4,664,356Mid-sized | 86.83 |
| Humane Animal Welfare SocietyEIN 39-6108644 | Animals | WI | $2,514,825Small | 89.00 |
| Humane IndianaEIN 35-0895837 | Animals | IN | $2,241,265Small | 86.88 |
| Humane PennsylvaniaEIN 23-1384936 | Animals | PA | $3,609,056Mid-sized | 86.38 |
| Humane Society for Southwest WashingtonEIN 91-0759124 | Animals | WA | $3,612,915Mid-sized | 81.52 |
| Humane Society InternationalEIN 52-1769464 | Animals | DC | $14,265,429Large | 87.97 |
| Humane Society of Boulder ValleyEIN 84-0152768 | Animals | CO | $6,028,806Mid-sized | 88.19 |
| Humane Society of Broward CountyEIN 59-6002321 | Animals | FL | $7,939,863Mid-sized | 84.66 |
| Humane Society of CharlotteEIN 58-1342479 | Animals | NC | $4,353,632Mid-sized | 87.18 |
| Humane Society of Greater Kansas CityEIN 48-0581965 | Animals | KS | $2,551,590Small | 81.15 |
| Humane Society of Harrisburg AreaEIN 23-1365361 | Animals | PA | $2,352,497Small | 86.84 |
| Humane Society of Memphis & Shelby CountyEIN 23-7236238 | Animals | TN | $1,924,009Small | 81.76 |
| Humane Society of PinellasEIN 59-0781650 | Animals | FL | $2,316,267Small | 85.53 |
| Humane Society of South MississippiEIN 64-6034439 | Animals | MS | $2,148,991Small | 89.35 |
| Humane Society of Southwest MissouriEIN 44-0665046 | Animals | MO | $1,483,758Small | 80.90 |
| Humane Society of Summit CountyEIN 23-7060744 | Animals | OH | $1,831,464Small | 83.63 |
| Humane Society of Vero Beach and Indian River CountyEIN 59-0863199 | Animals | FL | $3,581,376Mid-sized | 88.41 |
| Humane Society of West MichiganEIN 38-1360926 | Animals | MI | $1,980,677Small | 84.36 |
| Humane Society Silicon ValleyEIN 94-1196215 | Animals | CA | $11,941,402Mid-sized | 88.89 |
| Humanitarian Service ProjectEIN 36-3187979 | Human Services | IL | $1,220,218Small | 85.75 |
| Humanities TexasEIN 75-1493438 | Arts, Culture, Humanities | TX | $2,994,319Small | 85.74 |
| Hunger Free AmericaEIN 13-3471350 | Human Services | NY | $4,119,177Mid-sized | 88.51 |
| Hunger Network of Greater ClevelandEIN 34-1810545 | Human Services | OH | $11,884,594Mid-sized | 86.71 |
| Hunger Task ForceEIN 39-1345847 | Human Services | WI | $16,848,662Large | 89.56 |
| Hunter Museum of American ArtEIN 62-0511893 | Arts, Culture, Humanities | TN | $2,934,324Small | 83.82 |
| Hunter's Hope FoundationEIN 16-1552315 | Health | NY | $868,913Small | 84.32 |
| Huntington Medical Research InstitutesEIN 95-1757119 | Health | CA | $8,836,889Mid-sized | 86.43 |
| Huntington Theatre CompanyEIN 22-2659560 | Arts, Culture, Humanities | MA | $14,175,401Large | 86.60 |
| Huntsville Botanical GardenEIN 63-0800109 | Environment | AL | $4,048,002Mid-sized | 89.76 |
| Huntsville Symphony OrchestraEIN 63-0463802 | Arts, Culture, Humanities | AL | $2,008,399Small | 80.20 |
| Hydrocephalus AssociationEIN 94-3000301 | Health | MD | $4,756,366Mid-sized | 86.21 |
| ICAEIN 41-0979010 | Human Services | MN | $4,535,690Mid-sized | 89.58 |
| ICANEIN 86-0761030 | Human Services | AZ | $1,966,281Small | 82.37 |
| Idyllwild Arts FoundationEIN 95-1801279 | Education | CA | $26,431,187Large | 81.19 |
| IHCF African Christian HospitalsEIN 23-7258102 | International | AR | $972,858Small | 85.39 |
| Illinois Holocaust Museum & Education CenterEIN 36-3156154 | Arts, Culture, Humanities | IL | $8,417,466Mid-sized | 85.57 |
| Illinois Policy InstituteEIN 41-2057028 | Research and Public Policy | IL | $6,963,067Mid-sized | 84.41 |
| IMA World HealthEIN 52-2112460 | International | DC | $97,151,816Large | 82.32 |
| IMPACT WITH HOPEEIN 34-1470104 | International | OH | $6,103,153Mid-sized | 84.39 |
| In Touch FoundationEIN 58-2054582 | Religion | GA | $4,610,654Mid-sized | 85.55 |
| In Touch MinistriesEIN 58-1495310 | Religion | GA | $92,027,999Large | 86.14 |
| In Touch Mission InternationalEIN 94-2783852 | Religion | AZ | $1,372,833Small | 85.04 |
| Independence MediaEIN 22-2600747 | Arts, Culture, Humanities | PA | $2,758,153Small | 87.44 |
| Independence Seaport MuseumEIN 23-1584971 | Arts, Culture, Humanities | PA | $5,018,524Mid-sized | 81.35 |
| India Gospel OutreachEIN 33-0193797 | Religion | CA | $1,339,644Small | 85.94 |
| Indiana Historical SocietyEIN 35-0876384 | Arts, Culture, Humanities | IN | $12,091,643Mid-sized | 83.95 |