| LA OperaEIN 95-2096402 | Arts, Culture, Humanities | CA | $42,265,305Large | 87.42 |
| Lakeland Public TelevisionEIN 41-1265701 | Arts, Culture, Humanities | MN | $2,788,423Small | 87.20 |
| Lakeland Volunteers in MedicineEIN 52-2351630 | Health | FL | $1,812,580Small | 81.96 |
| Lakeshore Habitat for HumanityEIN 38-2893355 | Community Development | MI | $2,460,211Small | 88.18 |
| Lakeview Cemetery FoundationEIN 34-1429875 | Arts, Culture, Humanities | OH | $1,539,223Small | 81.69 |
| Lakeview PantryEIN 36-2734184 | Human Services | IL | $5,200,543Mid-sized | 87.11 |
| Lambda LegalEIN 23-7395681 | Human and Civil Rights | NY | $3,373,779Small | 81.46 |
| Land Stewardship ProjectEIN 41-1466054 | Environment | MN | $2,524,386Small | 87.93 |
| LAND studioEIN 34-1212421 | Environment | OH | $3,900,114Mid-sized | 86.27 |
| Langham PartnershipEIN 23-7417198 | Religion | AZ | $4,124,812Mid-sized | 81.10 |
| Lankenau Institute for Medical ResearchEIN 23-2175659 | Health | PA | $16,847,810Large | 81.99 |
| Las Vegas Rescue MissionEIN 23-7222330 | Human Services | NV | $5,012,654Mid-sized | 82.74 |
| Latino Health AccessEIN 33-0562943 | Human Services | CA | $2,557,543Small | 85.02 |
| Latino Policy ForumEIN 36-3676873 | Human and Civil Rights | IL | $1,400,304Small | 82.88 |
| LatinoJustice PRLDEFEIN 13-2722664 | Human and Civil Rights | NY | $2,720,183Small | 85.76 |
| Lauritzen GardensEIN 47-0659701 | Environment | NE | $6,507,988Mid-sized | 84.42 |
| Law Enforcement Legal Defense FundEIN 52-1095066 | Human and Civil Rights | VA | $1,632,586Small | 87.54 |
| Lawyers Alliance for New YorkEIN 13-2666432 | Human and Civil Rights | NY | $3,003,462Small | 87.33 |
| Lawyers' Committee for Civil Rights Under LawEIN 52-0799246 | Human and Civil Rights | DC | $7,241,908Mid-sized | 87.31 |
| Lazarus HouseEIN 04-2755382 | Human Services | MA | $8,732,769Mid-sized | 88.94 |
| Leader Dogs for the BlindEIN 38-1366931 | Human Services | MI | $14,964,355Large | 85.08 |
| Leadership Resources InternationalEIN 36-2972097 | Religion | IL | $3,155,098Small | 81.87 |
| Leadership RoundtableEIN 54-2174467 | Religion | DC | $2,362,890Small | 80.46 |
| League of American BicyclistsEIN 36-6206225 | Research and Public Policy | DC | $1,587,429Small | 81.45 |
| League of Education Voters FoundationEIN 91-2141507 | Education | WA | $3,258,126Small | 87.56 |
| League to Save Lake TahoeEIN 94-6128680 | Environment | CA | $2,194,842Small | 85.65 |
| Learning AllyEIN 13-1659345 | Education | NJ | $17,323,663Large | 80.95 |
| Lee Pesky Learning CenterEIN 13-3878574 | Education | ID | $1,453,064Small | 89.87 |
| Leg Up FarmEIN 23-2931834 | Health | PA | $2,724,018Small | 80.10 |
| Legacy Youth Tennis and EducationEIN 23-1747032 | Human Services | PA | $2,880,570Small | 83.24 |
| Legal Action Center of the City of New YorkEIN 13-2756320 | Human and Civil Rights | NY | $5,209,211Mid-sized | 86.67 |
| Legal Aid of Western MissouriEIN 43-0824638 | Human and Civil Rights | MO | $8,725,119Mid-sized | 85.86 |
| Legal Aid Society of San Mateo CountyEIN 94-1451894 | Human and Civil Rights | CA | $2,751,433Small | 89.37 |
| Legal Information for Families Today (LIFT)EIN 13-3910567 | Human and Civil Rights | NY | $1,812,443Small | 86.20 |
| Legal OutreachEIN 13-3214627 | Education | NY | $2,609,785Small | 87.22 |
| Legal Services for ChildrenEIN 51-0169463 | Human and Civil Rights | CA | $2,541,488Small | 89.89 |
| Les Turner ALS FoundationEIN 36-2916466 | Health | IL | $2,469,145Small | 85.71 |
| Levine Museum of the New SouthEIN 56-1748648 | Arts, Culture, Humanities | NC | $2,311,042Small | 83.95 |
| Lewy Body Dementia AssociationEIN 05-0577683 | Health | GA | $1,151,496Small | 89.94 |
| LGBTQ Victory InstituteEIN 52-1835268 | Human and Civil Rights | DC | $2,665,828Small | 81.71 |
| Liberty in North KoreaEIN 73-1710135 | International | CA | $2,117,955Small | 88.50 |
| Liberty USOEIN 23-1426011 | Human Services | PA | $2,249,799Small | 85.99 |
| Liberty Youth RanchEIN 38-3674666 | Human Services | FL | $879,430Small | 81.32 |
| Library Company of PhiladelphiaEIN 23-1370444 | Arts, Culture, Humanities | PA | $3,452,930Small | 86.21 |
| Life Action MinistriesEIN 38-2157686 | Religion | MI | $14,962,778Large | 87.94 |
| Life CentersEIN 31-1059740 | Human Services | IN | $1,470,473Small | 80.66 |
| Life Choices of MemphisEIN 62-1281799 | Health | TN | $1,061,899Small | 83.38 |
| Life for Relief and DevelopmentEIN 95-4402149 | International | MI | $10,068,604Mid-sized | 87.25 |
| LifeFlight FoundationEIN 52-2377085 | Health | ME | $1,785,307Small | 83.37 |
| Lifeline Christian MissionEIN 31-0999791 | Religion | OH | $8,238,442Mid-sized | 87.05 |
| Lifting GenerationsEIN 80-0001164 | International | UT | $1,750,813Small | 81.62 |
| LightHawkEIN 84-0852104 | Environment | CO | $1,589,618Small | 85.34 |
| Lighthouse Family RetreatEIN 58-2509728 | Health | GA | $2,313,452Small | 83.31 |
| Lighthouse Ministries, FloridaEIN 59-1722768 | Human Services | FL | $3,656,333Mid-sized | 85.85 |
| Ligonier MinistriesEIN 25-1298611 | Religion | FL | $21,587,586Large | 89.44 |
| Lincoln Children's MuseumEIN 47-0716636 | Arts, Culture, Humanities | NE | $1,529,973Small | 86.62 |
| Lincoln Park ZooEIN 36-2512404 | Animals | IL | $43,412,852Large | 85.43 |
| Lindsay Wildlife MuseumEIN 94-6104179 | Arts, Culture, Humanities | CA | $2,679,461Small | 87.12 |
| LINK Unlimited ScholarsEIN 23-7386928 | Education | IL | $2,710,923Small | 83.38 |
| Literacy Assistance CenterEIN 13-3179618 | Education | NY | $1,917,881Small | 86.84 |