| Big Brothers Big Sisters of Central ArizonaEIN 86-0205254 | Human Services | AZ | $2,198,310Small | 86.11 |
| Big Brothers Big Sisters of Central CarolinasEIN 56-2264009 | Human Services | NC | $2,122,393Small | 86.69 |
| Big Brothers Big Sisters of Central IndianaEIN 35-1323831 | Human Services | IN | $2,235,849Small | 87.96 |
| Big Brothers Big Sisters of ColoradoEIN 23-7161796 | Human Services | CO | $3,046,953Small | 80.18 |
| Big Brothers Big Sisters of Eastern MissouriEIN 43-0669085 | Human Services | MO | $4,922,339Mid-sized | 89.66 |
| Big Brothers Big Sisters of Greater Kansas CityEIN 43-6068464 | Human Services | MO | $3,900,296Mid-sized | 82.72 |
| Big Brothers Big Sisters of Greater Los AngelesEIN 95-1904857 | Human Services | CA | $3,769,785Mid-sized | 86.66 |
| Big Brothers Big Sisters of Metro AtlantaEIN 58-0861895 | Human Services | GA | $4,054,562Mid-sized | 88.87 |
| Big Brothers Big Sisters of Metro MilwaukeeEIN 39-1239687 | Human Services | WI | $2,082,340Small | 84.35 |
| Big Brothers Big Sisters of Middle TennesseeEIN 23-7056024 | Human Services | TN | $2,799,769Small | 87.61 |
| Big Brothers Big Sisters of New York CityEIN 13-5600383 | Human Services | NY | $10,979,467Mid-sized | 88.90 |
| Big Brothers Big Sisters of Northeast IndianaEIN 35-1271943 | Human Services | IN | $2,267,416Small | 87.87 |
| Big Brothers Big Sisters of Palm Beach and Martin CountiesEIN 59-2676889 | Human Services | FL | $847,627Small | 83.33 |
| Big Brothers Big Sisters of South TexasEIN 74-1897630 | Human Services | TX | $2,993,424Small | 87.96 |
| Big Brothers Big Sisters of St. Lucie, Indian River & Okeechobee CountiesEIN 59-2455513 | Human Services | FL | $1,378,398Small | 81.82 |
| Big Brothers Big Sisters of Tampa BayEIN 59-2173085 | Human Services | FL | $4,990,990Mid-sized | 88.09 |
| Big Brothers Big Sisters of the Greater Twin CitiesEIN 32-0017737 | Human Services | MN | $5,810,205Mid-sized | 80.30 |
| Big Brothers Big Sisters of the Sun CoastEIN 59-1361826 | Human Services | FL | $2,506,829Small | 88.12 |
| Big Brothers Big Sisters of the TriangleEIN 56-2109717 | Human Services | NC | $841,613Small | 86.38 |
| Big City MountaineersEIN 65-0200163 | Human Services | CO | $1,036,772Small | 87.09 |
| Big Green Scholarship FoundationEIN 55-0631935 | Education | WV | $3,736,494Mid-sized | 82.14 |
| Big ThoughtEIN 75-2170035 | Education | TX | $7,097,230Mid-sized | 83.62 |
| Bike & BuildEIN 36-4524531 | Community Development | PA | $1,117,167Small | 83.08 |
| Bikes Not BombsEIN 04-3138753 | International | MA | $1,482,741Small | 86.84 |
| Bill of Rights InstituteEIN 48-0891418 | Education | VA | $3,151,238Small | 83.26 |
| Biomimicry InstituteEIN 86-1153859 | Environment | MT | $945,865Small | 80.43 |
| BioneersEIN 85-0432731 | Environment | NM | $4,165,702Mid-sized | 85.37 |
| Bird Street Community CenterEIN 04-2708670 | Human Services | MA | $1,635,684Small | 80.05 |
| Bishop Sullivan CenterEIN 43-1750848 | Human Services | MO | $1,726,054Small | 84.68 |
| Black AIDS InstituteEIN 95-4742741 | Health | CA | $2,147,395Small | 88.86 |
| Blandford Nature CenterEIN 20-0739420 | Environment | MI | $1,358,816Small | 85.35 |
| Blank Park ZooEIN 42-1171821 | Animals | IA | $7,017,106Mid-sized | 88.24 |
| BlithewoldEIN 05-0503407 | Arts, Culture, Humanities | RI | $1,694,452Small | 89.34 |
| Blue Ridge Public RadioEIN 58-1445328 | Arts, Culture, Humanities | NC | $2,365,620Small | 88.06 |
| Blue Water BaltimoreEIN 52-1420138 | Environment | MD | $3,712,321Mid-sized | 89.35 |
| BLUEBARN TheatreEIN 47-0742394 | Arts, Culture, Humanities | NE | $718,171Small | 83.20 |
| Bluegreen Alliance FoundationEIN 20-3477309 | Environment | MN | $3,883,863Mid-sized | 88.93 |
| Boca Raton Museum of ArtEIN 59-6019851 | Arts, Culture, Humanities | FL | $5,574,318Mid-sized | 85.90 |
| Bolder OptionsEIN 41-1909408 | Human Services | MN | $1,005,288Small | 81.41 |
| Bonei OlamEIN 11-3473757 | Health | NY | $9,800,311Mid-sized | 85.03 |
| Book TrustEIN 20-4124164 | Education | CO | $4,309,861Mid-sized | 89.78 |
| Boone and Crockett ClubEIN 81-0438290 | Animals | MT | $3,085,806Small | 85.24 |
| Born Free USAEIN 94-6187633 | Animals | MD | $2,716,257Small | 88.05 |
| Boston After School & BeyondEIN 20-1308560 | Human Services | MA | $2,594,596Small | 89.86 |
| Boston AthenæumEIN 04-2104852 | Arts, Culture, Humanities | MA | $7,978,842Mid-sized | 87.70 |
| Boston BalletEIN 04-2312734 | Arts, Culture, Humanities | MA | $34,959,006Large | 86.74 |
| Boston Bar FoundationEIN 04-6111344 | Human and Civil Rights | MA | $1,643,676Small | 85.63 |
| Boston Children's MuseumEIN 04-2103993 | Arts, Culture, Humanities | MA | $10,009,528Mid-sized | 89.89 |
| Boston Landmarks OrchestraEIN 31-1750843 | Arts, Culture, Humanities | MA | $1,212,568Small | 86.17 |
| Boston Latin School AssociationEIN 04-6035973 | Education | MA | $5,178,794Mid-sized | 87.24 |
| Boston Lyric OperaEIN 04-2469627 | Arts, Culture, Humanities | MA | $7,961,986Mid-sized | 88.03 |
| Boston Neighborhood NetworkEIN 04-2784953 | Arts, Culture, Humanities | MA | $2,104,336Small | 83.30 |
| Boston Philharmonic OrchestraEIN 04-2678312 | Arts, Culture, Humanities | MA | $2,782,364Small | 83.51 |
| Boston Rescue MissionEIN 04-2104726 | Human Services | MA | $3,126,857Small | 88.37 |
| Boston Symphony OrchestraEIN 04-2103550 | Arts, Culture, Humanities | MA | $103,630,393Large | 84.74 |
| Botanical Research Institute of TexasEIN 75-2198196 | Research and Public Policy | TX | $5,266,139Mid-sized | 85.94 |
| Boulder Shelter for the HomelessEIN 84-1041149 | Human Services | CO | $2,476,170Small | 88.71 |
| Bowers MuseumEIN 33-0106161 | Arts, Culture, Humanities | CA | $5,365,378Mid-sized | 82.15 |
| Boy Scouts of AmericaEIN 25-0965214 | Human Services | PA | $6,991,409Mid-sized | 89.18 |
| Boy Scouts of America Blue Ridge CouncilEIN 57-0314427 | Human Services | SC | $2,243,186Small | 85.14 |