| New York Road RunnersEIN 13-2949483 | Human Services | NY | $88,751,028Large | 90.80 |
| New York Society for the Prevention of Cruelty to ChildrenEIN 13-1624134 | Human Services | NY | $3,748,523Mid-sized | 87.28 |
| New York State Sheriffs' Association InstituteEIN 22-2272582 | Human Services | NY | $2,575,460Small | 76.36 |
| New York Studio SchoolEIN 13-6167281 | Education | NY | $2,505,997Small | 79.11 |
| New York Theatre WorkshopEIN 13-3131491 | Arts, Culture, Humanities | NY | $6,258,459Mid-sized | 93.46 |
| New York Women's FoundationEIN 13-3457287 | Human and Civil Rights | NY | $13,855,149Large | 91.73 |
| New Yorkers For ChildrenEIN 13-3904537 | Human Services | NY | $2,920,977Small | 81.85 |
| NEXT for AUTISMEIN 57-1136147 | Health | NY | $2,474,471Small | 87.68 |
| NextbookEIN 41-2116973 | Religion | NY | $3,350,326Small | 69.42 |
| Niagara Aquarium FoundationEIN 16-1448764 | Animals | NY | $2,371,210Small | 82.98 |
| Nontraditional Employment for WomenEIN 13-3272001 | Human Services | NY | $2,620,714Small | 81.64 |
| North American Conference on Ethiopian JewryEIN 13-3187021 | Education | NY | $2,585,628Small | 83.14 |
| North Shore Animal League AmericaEIN 11-1666852 | Animals | NY | $41,531,218Large | 83.38 |
| NPower Inc.EIN 13-4145441 | Human Services | NY | $11,876,339Mid-sized | 95.50 |
| NYC Outward Bound SchoolsEIN 13-3471084 | Education | NY | $6,541,364Mid-sized | 97.26 |
| Ohr Somayach InternationalEIN 13-3503155 | Religion | NY | $4,063,985Mid-sized | 70.25 |
| Ohr Torah Stone Colleges and Graduate ProgramsEIN 13-3275531 | Religion | NY | $5,013,619Mid-sized | 81.38 |
| Oliver ScholarsEIN 13-3248876 | Education | NY | $4,018,563Mid-sized | 96.97 |
| One Israel Fund Ltd.EIN 11-3195338 | International | NY | $3,470,381Small | 92.50 |
| OneVoice MovementEIN 30-0102398 | International | NY | $3,731,582Mid-sized | 88.81 |
| OPERA AmericaEIN 20-3520577 | Arts, Culture, Humanities | NY | $7,895,530Mid-sized | 91.83 |
| Orbis InternationalEIN 23-7297651 | International | NY | $209,113,219Large | 95.47 |
| Orchestra of St. Luke'sEIN 51-0201839 | Arts, Culture, Humanities | NY | $7,749,571Mid-sized | 86.11 |
| Orpheus Chamber OrchestraEIN 23-7362572 | Arts, Culture, Humanities | NY | $2,993,130Small | 78.95 |
| ORT AmericaEIN 13-5562424 | Education | NY | $15,138,099Large | 90.27 |
| OutRight Action InternationalEIN 94-3139952 | Human and Civil Rights | NY | $2,691,363Small | 88.00 |
| Ovarian Cancer Research AllianceEIN 13-3806788 | Health | NY | $10,805,177Mid-sized | 93.28 |
| P'eylim Lev L'AchimEIN 13-5643666 | Human Services | NY | $4,222,563Mid-sized | 58.16 |
| Pajama ProgramEIN 02-0588068 | Human Services | NY | $5,715,822Mid-sized | 98.13 |
| Paleontological Research InstitutionEIN 15-0554849 | Arts, Culture, Humanities | NY | $2,561,752Small | 78.74 |
| Panthera CorporationEIN 20-4668756 | Animals | NY | $12,225,372Mid-sized | 96.87 |
| Pardes Institute of Jewish Studies, North AmericaEIN 22-2594099 | Education | NY | $4,631,629Mid-sized | 87.65 |
| Park Avenue ArmoryEIN 13-4086800 | Arts, Culture, Humanities | NY | $25,931,022Large | 91.92 |
| Parkinson's FoundationEIN 13-1866796 | Health | NY | $26,963,779Large | 90.88 |
| Partnership for After School EducationEIN 13-3976066 | Education | NY | $1,598,182Small | 79.17 |
| Partnership for Drug-Free KidsEIN 13-3413627 | Health | NY | $7,484,044Mid-sized | 90.81 |
| Partnership for the HomelessEIN 13-3732698 | Human Services | NY | $3,739,289Mid-sized | 79.55 |
| Partnership with ChildrenEIN 13-5596751 | Education | NY | $10,401,873Mid-sized | 95.13 |
| Paul Taylor Dance FoundationEIN 13-2665475 | Arts, Culture, Humanities | NY | $9,680,646Mid-sized | 89.24 |
| PCI Media ImpactEIN 13-3280193 | International | NY | $4,681,975Mid-sized | 92.32 |
| Pegasus Therapeutic RidingEIN 06-0932894 | Health | NY | $1,313,219Small | 65.88 |
| PEN American CenterEIN 13-3447888 | Arts, Culture, Humanities | NY | $6,594,856Mid-sized | 92.27 |
| PENCILEIN 22-3384302 | Education | NY | $2,883,792Small | 78.58 |
| Per ScholasEIN 04-3252955 | Human Services | NY | $11,859,128Mid-sized | 93.35 |
| Peter Westbrook FoundationEIN 13-3412917 | Human Services | NY | $607,425Small | 89.28 |
| Physicians for Human RightsEIN 22-2488437 | International | NY | $6,518,811Mid-sized | 92.10 |
| Physicians for Reproductive HealthEIN 13-3693391 | Human and Civil Rights | NY | $5,505,425Mid-sized | 98.88 |
| PILnetEIN 20-5087783 | Human and Civil Rights | NY | $2,197,652Small | 79.59 |
| Planned Parenthood Federation of AmericaEIN 13-1644147 | Health | NY | $317,843,167Large | 92.74 |
| Planned Parenthood Hudson PeconicEIN 11-2454790 | Health | NY | $18,935,544Large | 84.44 |
| Planned Parenthood of New York CityEIN 13-2621497 | Health | NY | $51,515,907Large | 92.72 |
| Planned Parenthood of the Southern Finger LakesEIN 16-0953368 | Health | NY | $6,862,987Mid-sized | 83.77 |
| Planting Fields FoundationEIN 11-1770097 | Environment | NY | $2,404,069Small | 87.56 |
| Playwrights HorizonsEIN 13-2805131 | Arts, Culture, Humanities | NY | $12,688,674Mid-sized | 88.18 |
| Poets & WritersEIN 13-2682458 | Arts, Culture, Humanities | NY | $4,077,742Mid-sized | 85.25 |
| Population CouncilEIN 13-1687001 | Health | NY | $85,432,557Large | 86.68 |
| Port Chester Carver CenterEIN 13-1832949 | Human Services | NY | $4,023,916Mid-sized | 94.74 |
| PowerMyLearningEIN 13-3935309 | Education | NY | $11,164,760Mid-sized | 92.61 |
| Prep for PrepEIN 13-2613383 | Education | NY | $11,714,371Mid-sized | 90.08 |
| Primary StagesEIN 13-3258765 | Arts, Culture, Humanities | NY | $3,161,816Small | 67.53 |