| Trinity Broadcasting of ArizonaEIN 86-0335082 | Religion | AZ | $2,715,322Small | 65.05 |
| Trinity Broadcasting of IndianaEIN 31-1016441 | Religion | IN | $3,214,821Small | 65.12 |
| Trinity Broadcasting of New YorkEIN 14-1631995 | Religion | NY | $4,518,055Mid-sized | 66.12 |
| Trinity Broadcasting of OklahomaEIN 73-1011191 | Religion | OK | $1,297,301Small | 65.82 |
| Trinity Broadcasting of TexasEIN 74-1945661 | Religion | TX | $4,212,032Mid-sized | 66.14 |
| Trinity Broadcasting of WashingtonEIN 91-0996619 | Religion | WA | $2,104,124Small | 66.65 |
| Trinity Counseling ServiceEIN 22-2185298 | Human Services | NJ | $1,386,822Small | 75.61 |
| Trinity Habitat for HumanityEIN 75-2239189 | Community Development | TX | $7,425,099Mid-sized | 95.23 |
| Trinity Repertory CompanyEIN 22-2547262 | Arts, Culture, Humanities | RI | $9,185,193Mid-sized | 90.82 |
| Troops DirectEIN 27-3046842 | Human Services | CA | $4,469,769Mid-sized | 84.28 |
| Truckee River Watershed CouncilEIN 91-1818748 | Environment | CA | $2,510,386Small | 76.89 |
| Truman Center for National PolicyEIN 52-1080919 | Research and Public Policy | DC | $2,520,516Small | 63.81 |
| Trustees for AlaskaEIN 92-6010379 | Environment | AK | $1,214,163Small | 85.67 |
| Truth For LifeEIN 34-1787585 | Religion | OH | $10,092,567Mid-sized | 97.04 |
| Truth for Today World Mission SchoolEIN 71-0753278 | Religion | AR | $1,774,755Small | 81.61 |
| Tucker-Maxon Oral SchoolEIN 93-0391592 | Education | OR | $1,800,099Small | 86.33 |
| Tucson Museum of Art and Historic BlockEIN 86-6006371 | Arts, Culture, Humanities | AZ | $2,903,286Small | 83.02 |
| Tuesday's ChildrenEIN 52-2347446 | Human Services | NY | $1,942,937Small | 88.09 |
| Tukabatchee Area Council Boy Scouts of AmericaEIN 63-0302109 | Human Services | AL | $1,291,416Small | 73.36 |
| Tulsa Area United WayEIN 73-0580283 | Community Development | OK | $24,720,523Large | 91.55 |
| Tulsa BalletEIN 73-0667485 | Arts, Culture, Humanities | OK | $7,005,557Mid-sized | 92.14 |
| Tulsa CARESEIN 73-1388569 | Health | OK | $1,934,329Small | 81.98 |
| Tulsa Day Center for the HomelessEIN 73-1557819 | Human Services | OK | $3,282,558Small | 93.12 |
| Tulsa Habitat for HumanityEIN 73-1325063 | Community Development | OK | $5,413,408Mid-sized | 91.68 |
| Tulsa Library TrustEIN 51-0165881 | Arts, Culture, Humanities | OK | $9,385,003Mid-sized | 84.34 |
| Tulsa OperaEIN 73-0643311 | Arts, Culture, Humanities | OK | $2,526,755Small | 67.47 |
| Tulsa Zoo FriendsEIN 73-0930870 | Animals | OK | $24,871,589Large | 85.13 |
| Turner House Children's ClinicEIN 48-1151382 | Health | KS | $3,010,233Small | 88.97 |
| Turning PointEIN 33-0095805 | Religion | CA | $51,279,303Large | 83.02 |
| Turning Pointe Autism FoundationEIN 26-1286022 | Health | IL | $2,763,599Small | 94.74 |
| Turnstone Center for Disabled Children and AdultsEIN 35-0913541 | Human Services | IN | $6,027,867Mid-sized | 92.63 |
| Turtle Bay Exploration ParkEIN 68-0236299 | Arts, Culture, Humanities | CA | $5,807,778Mid-sized | 80.07 |
| Turtle ConservancyEIN 20-2899240 | Animals | CA | $3,216,720Small | 82.66 |
| Turtle Island Restoration NetworkEIN 91-1818080 | Animals | CA | $1,669,147Small | 96.91 |
| Twin Cities Habitat for HumanityEIN 36-3363171 | Community Development | MN | $18,388,178Large | 85.85 |
| Twin Cities Public TelevisionEIN 41-0769851 | Arts, Culture, Humanities | MN | $36,605,032Large | 95.52 |
| Twin Cities R!SEEIN 41-1761118 | Human Services | MN | $3,488,160Small | 83.36 |
| Two River Theater CompanyEIN 52-1857757 | Arts, Culture, Humanities | NJ | $6,348,940Mid-sized | 90.94 |
| Two Ten Footwear FoundationEIN 22-2579809 | Human Services | MA | $5,594,243Mid-sized | 90.26 |
| U.S. Dream AcademyEIN 59-3514841 | Human Services | MD | $2,573,866Small | 76.25 |
| U.S. PIRG Education FundEIN 52-1384240 | Human and Civil Rights | MA | $1,838,729Small | 72.89 |
| U.S. Ski and Snowboard Team FoundationEIN 84-6030639 | Human Services | UT | $12,608,521Mid-sized | 84.76 |
| U.S., Inc.EIN 38-2418377 | Research and Public Policy | MI | $1,838,596Small | 75.70 |
| UCP Wheels for HumanityEIN 95-4581144 | International | CA | $6,086,262Mid-sized | 88.31 |
| Uih Family PartnersEIN 21-0635048 | Human Services | NJ | $1,230,248Small | 79.97 |
| UJA Federation of GreenwichEIN 06-6068624 | Community Development | CT | $1,986,161Small | 84.08 |
| UJA-Federation of New YorkEIN 51-0172429 | Community Development | NY | $236,483,000Large | 89.47 |
| Ukrainian Catholic Education FoundationEIN 36-4126296 | Religion | IL | $5,822,751Mid-sized | 91.78 |
| ULI FoundationEIN 23-7133957 | Community Development | DC | $6,498,365Mid-sized | 90.36 |
| Umoja Student Development CorporationEIN 36-4263664 | Education | IL | $2,706,226Small | 92.18 |
| UnboundEIN 43-1243999 | International | KS | $128,095,891Large | 91.05 |
| UNCFEIN 13-1624241 | Education | DC | $171,722,769Large | 88.22 |
| Uncommon SchoolsEIN 31-1488698 | Education | NY | $42,868,589Large | 88.40 |
| UNICEF USAEIN 13-1760110 | International | NY | $512,770,720Large | 83.94 |
| UnidosUSEIN 86-0212873 | Human and Civil Rights | DC | $31,634,959Large | 90.28 |
| Union Gospel Mission of Grays HarborEIN 91-0580853 | Human Services | WA | $842,239Small | 82.79 |
| Union Gospel Mission of Tarrant CountyEIN 75-6054677 | Human Services | TX | $7,236,943Mid-sized | 89.77 |
| Union Gospel Mission Twin CitiesEIN 41-0705847 | Human Services | MN | $15,480,488Large | 85.46 |
| Union Gospel Mission, SacramentoEIN 94-6103618 | Human Services | CA | $3,824,237Mid-sized | 81.57 |
| Union League Boys & Girls ClubsEIN 36-2167939 | Human Services | IL | $5,382,975Mid-sized | 94.07 |