| Animal Welfare InstituteEIN 13-5655952 | Animals | DC | $2,737,309Small | 92.92 |
| Animal Welfare LeagueEIN 36-2235155 | Animals | IL | $6,855,668Mid-sized | 91.39 |
| Animal Welfare League of AlexandriaEIN 54-0796610 | Animals | VA | $2,882,177Small | 90.45 |
| Animal Welfare League of ArlingtonEIN 54-0603502 | Animals | VA | $3,195,704Small | 91.63 |
| Animal Welfare SocietyEIN 23-7018176 | Animals | ME | $3,126,373Small | 95.22 |
| Animals Asia Foundation LimitedEIN 31-1802788 | Animals | CA | $1,598,112Small | 86.12 |
| Animals' AngelsEIN 20-8780367 | Animals | MD | $906,993Small | 83.65 |
| Anita Borg InstituteEIN 77-0480427 | Education | CA | $19,390,962Large | 92.66 |
| Anne Arundel County Food BankEIN 52-1660473 | Human Services | MD | $3,890,270Mid-sized | 78.71 |
| Answers in GenesisEIN 33-0596423 | Religion | KY | $22,980,427Large | 76.50 |
| Anti-Defamation LeagueEIN 13-1818723 | Human and Civil Rights | NY | $63,917,573Large | 78.65 |
| Any Baby Can of San AntonioEIN 74-2684333 | Health | TX | $3,063,243Small | 90.32 |
| AORN FoundationEIN 84-1193583 | Health | CO | $1,800,377Small | 87.08 |
| Apartment LifeEIN 75-2868621 | Community Development | TX | $13,791,829Large | 85.68 |
| APhA FoundationEIN 52-6039142 | Research and Public Policy | DC | $1,640,653Small | 73.17 |
| Aplastic Anemia & MDS International FoundationEIN 52-1336903 | Health | MD | $6,448,619Mid-sized | 91.51 |
| Apollo Theater FoundationEIN 13-3630066 | Arts, Culture, Humanities | NY | $16,923,763Large | 89.07 |
| Apollo's FireEIN 34-1696842 | Arts, Culture, Humanities | OH | $1,874,985Small | 86.54 |
| Appalachia Service ProjectEIN 62-0989383 | Community Development | TN | $11,166,665Mid-sized | 92.92 |
| Appalachian Mountain ClubEIN 04-6001677 | Environment | MA | $31,787,810Large | 95.87 |
| Appalachian Trail ConservancyEIN 52-6046689 | Environment | WV | $9,331,050Mid-sized | 94.19 |
| Appalachian VoicesEIN 56-2049956 | Environment | NC | $2,237,713Small | 100.00 |
| AppalshopEIN 61-0890210 | Arts, Culture, Humanities | KY | $1,747,193Small | 81.02 |
| Appeal of Conscience FoundationEIN 52-6062870 | International | NY | $2,013,717Small | 86.70 |
| Appell Center for the Performing ArtsEIN 23-2053382 | Arts, Culture, Humanities | PA | $4,336,351Mid-sized | 86.05 |
| AppleseedEIN 52-1835698 | Human and Civil Rights | DC | $1,074,765Small | 77.73 |
| Aquarium of the PacificEIN 33-0532354 | Animals | CA | $31,141,128Large | 91.67 |
| Arboretum FoundationEIN 91-0613583 | Environment | WA | $1,228,490Small | 77.79 |
| Arby's FoundationEIN 58-1692997 | Human Services | GA | $8,124,464Mid-sized | 94.58 |
| Archaeological ConservancyEIN 95-3403273 | Arts, Culture, Humanities | NM | $3,693,315Mid-sized | 96.66 |
| Archaeology SouthwestEIN 86-0640183 | Arts, Culture, Humanities | AZ | $1,591,501Small | 92.92 |
| Arctic Barnabas MinistriesEIN 92-0172389 | Religion | AK | $1,115,575Small | 77.91 |
| Areivim Philanthropic GroupEIN 20-8024537 | Community Development | NY | $1,236,719Small | 80.54 |
| Ariel MinistriesEIN 74-1930400 | Religion | TX | $2,257,189Small | 58.03 |
| Arizona Animal Welfare League & SPCAEIN 23-7149453 | Animals | AZ | $4,398,395Mid-sized | 93.87 |
| Arizona Christian School Tuition OrganizationEIN 86-0931047 | Education | AZ | $19,281,533Large | 91.05 |
| Arizona Community FoundationEIN 86-0348306 | Community Development | AZ | $67,913,276Large | 92.98 |
| Arizona Hemophilia AssociationEIN 86-0209257 | Health | AZ | $2,299,635Small | 82.00 |
| Arizona Humane SocietyEIN 86-0135567 | Animals | AZ | $18,373,050Large | 90.64 |
| Arizona OperaEIN 23-7169261 | Arts, Culture, Humanities | AZ | $6,211,715Mid-sized | 85.69 |
| Arizona Private Education Scholarship FundEIN 86-0958161 | Education | AZ | $6,349,350Mid-sized | 94.74 |
| Arizona Science CenterEIN 86-0390558 | Arts, Culture, Humanities | AZ | $9,868,682Mid-sized | 81.77 |
| Arizona Women's Education and EmploymentEIN 86-0412509 | Human Services | AZ | $2,252,823Small | 73.68 |
| Arizona-Sonora Desert MuseumEIN 86-0111675 | Arts, Culture, Humanities | AZ | $10,274,415Mid-sized | 89.88 |
| Arkansas Baptist Children's Homes and Family MinistriesEIN 71-0296619 | Human Services | AR | $4,388,581Mid-sized | 86.51 |
| Arkansas FoodbankEIN 71-0596734 | Human Services | AR | $43,348,876Large | 90.22 |
| Arkansas Repertory Theatre CompanyEIN 71-0480336 | Arts, Culture, Humanities | AR | $4,642,033Mid-sized | 82.15 |
| Arkansas Sheriffs' Youth RanchesEIN 71-0471266 | Human Services | AR | $2,273,259Small | 83.59 |
| Arkansas Single Parent Scholarship Fund ProgramEIN 71-0704088 | Education | AR | $2,294,632Small | 89.38 |
| Arkansas Symphony OrchestraEIN 71-6059542 | Arts, Culture, Humanities | AR | $3,232,760Small | 81.79 |
| Arlington Food Assistance CenterEIN 54-1473207 | Human Services | VA | $5,583,702Mid-sized | 96.40 |
| Arlington Free ClinicEIN 54-1671883 | Health | VA | $4,036,752Mid-sized | 90.45 |
| Arlington Street People's Assistance NetworkEIN 54-1615993 | Human Services | VA | $4,004,806Mid-sized | 90.58 |
| Arm In ArmEIN 22-3198464 | Human Services | NJ | $2,461,297Small | 95.29 |
| Armed Services YMCAEIN 36-3274346 | Human Services | VA | $22,350,334Large | 93.12 |
| Armenian Assembly of AmericaEIN 52-1614093 | International | DC | $3,569,175Mid-sized | 90.04 |
| Armenian General Benevolent UnionEIN 13-5600421 | International | NY | $23,318,407Large | 85.03 |
| Armenian Relief and Development Association (ARDA)EIN 23-7089113 | International | CA | $863,730Small | 66.81 |
| Arms of HopeEIN 75-0904045 | Human Services | TX | $9,318,892Mid-sized | 87.35 |
| Army Emergency ReliefEIN 53-0196552 | Human Services | VA | $28,198,705Large | 93.98 |