| Children's Restoration NetworkEIN 58-2068230 | Human Services | GA | $2,901,259Small | 86.39 |
| Children's RightsEIN 13-3801864 | Human Services | NY | $5,161,356Mid-sized | 81.71 |
| Children's Scholarship FundEIN 13-4002189 | Education | NY | $22,111,290Large | 89.39 |
| Children's Theatre CompanyEIN 41-1254553 | Arts, Culture, Humanities | MN | $12,400,825Mid-sized | 84.30 |
| Children's Theatre of MadisonEIN 39-1579813 | Arts, Culture, Humanities | WI | $1,620,120Small | 80.54 |
| Children's Tumor FoundationEIN 13-2298956 | Health | NY | $12,638,073Mid-sized | 85.15 |
| ChildsplayEIN 86-0336473 | Arts, Culture, Humanities | AZ | $3,377,552Small | 88.14 |
| China Institute in AmericaEIN 13-1623937 | International | NY | $6,411,288Mid-sized | 83.96 |
| China Outreach MinistriesEIN 52-0883435 | Religion | PA | $3,260,254Small | 83.65 |
| Chinati FoundationEIN 74-2340423 | Arts, Culture, Humanities | TX | $2,994,571Small | 82.64 |
| CHIP of South Hampton RoadsEIN 54-1893166 | Human Services | VA | $1,204,022Small | 81.57 |
| CHN Housing PartnersEIN 34-1346763 | Community Development | OH | $29,894,702Large | 85.57 |
| Choral ArtsEIN 52-0895826 | Arts, Culture, Humanities | DC | $1,716,197Small | 85.69 |
| Chorus AmericaEIN 23-2062595 | Arts, Culture, Humanities | DC | $1,317,271Small | 83.19 |
| Christ for HumanityEIN 73-1421083 | International | OK | $2,320,861Small | 82.26 |
| Christ HouseEIN 52-1362103 | Human Services | DC | $4,017,498Mid-sized | 89.82 |
| Christ Reaching Asia Mission WorldwideEIN 35-2047209 | International | IN | $1,531,199Small | 84.00 |
| Christ's Haven for ChildrenEIN 23-7164673 | Human Services | TX | $2,639,279Small | 87.36 |
| Christian Aid MinistriesEIN 34-1344364 | International | OH | $122,451,700Large | 87.02 |
| Christian Community Action, ConnecticutEIN 06-0841885 | Human Services | CT | $1,743,577Small | 87.42 |
| Christian Community Action, TexasEIN 23-7319371 | Human Services | TX | $4,628,975Mid-sized | 85.31 |
| Christian HELP FoundationEIN 59-3107271 | Human Services | FL | $1,643,685Small | 86.67 |
| Christian Medical & Dental AssociationsEIN 36-2284267 | Religion | TN | $12,214,968Mid-sized | 89.73 |
| Christian Service Center for Central FloridaEIN 59-1353031 | Human Services | FL | $1,396,639Small | 84.23 |
| Christian Solidarity InternationalEIN 33-0826951 | Religion | CA | $1,186,127Small | 88.46 |
| Christian UnionEIN 22-3834440 | Religion | NJ | $10,913,876Mid-sized | 89.74 |
| Christine Ann Domestic Abuse ServicesEIN 39-1441770 | Human Services | WI | $1,271,189Small | 81.30 |
| Chrysalis Shelter for Victims of Domestic ViolenceEIN 86-0447620 | Human Services | AZ | $2,974,397Small | 88.45 |
| Church World ServiceEIN 13-4080201 | International | IN | $65,527,734Large | 83.94 |
| Churches of Christ Disaster Relief EffortEIN 62-1560072 | Human Services | TN | $7,348,103Mid-sized | 85.15 |
| Cibolo Nature Center & FarmEIN 74-2564700 | Environment | TX | $3,672,517Mid-sized | 85.33 |
| Cincinnati BalletEIN 31-6050354 | Arts, Culture, Humanities | OH | $9,444,521Mid-sized | 87.20 |
| Cincinnati Parks FoundationEIN 31-1429016 | Environment | OH | $1,059,563Small | 89.02 |
| Cincinnati Public RadioEIN 31-1410636 | Arts, Culture, Humanities | OH | $5,945,935Mid-sized | 86.02 |
| CinequestEIN 77-0250734 | Arts, Culture, Humanities | CA | $1,297,850Small | 88.19 |
| Circle Health ServicesEIN 23-7078501 | Health | OH | $5,547,953Mid-sized | 88.77 |
| Circle Of ConcernEIN 23-7085010 | Human Services | MO | $2,170,713Small | 86.52 |
| CIS Development FoundationEIN 22-3304404 | International | NJ | $41,239,855Large | 83.73 |
| Citizen SchoolsEIN 04-3259160 | Education | MA | $20,565,491Large | 85.00 |
| Citizens Against Government WasteEIN 52-1363952 | Human and Civil Rights | DC | $3,768,713Mid-sized | 83.69 |
| Citizens Commission on Human RightsEIN 68-0005541 | Human and Civil Rights | CA | $3,592,409Mid-sized | 80.30 |
| Citizens for Responsibility and Ethics in WashingtonEIN 03-0445391 | Human and Civil Rights | DC | $1,995,677Small | 81.04 |
| Citizens' Committee for Children of New YorkEIN 13-5618593 | Human Services | NY | $2,913,471Small | 88.26 |
| City AcademyEIN 31-1619379 | Education | MO | $3,936,148Mid-sized | 86.36 |
| City HarvestEIN 13-3170676 | Human Services | NY | $123,039,582Large | 87.08 |
| City MissionEIN 25-1051749 | Human Services | PA | $6,720,515Mid-sized | 82.31 |
| City of RefugeEIN 58-2194642 | Human Services | GA | $8,064,665Mid-sized | 86.10 |
| City Rescue Mission, Oklahoma CityEIN 73-0713883 | Human Services | OK | $6,209,143Mid-sized | 89.00 |
| City TheatreEIN 25-1554580 | Arts, Culture, Humanities | PA | $3,008,701Small | 86.90 |
| CityteamEIN 94-1501265 | Human Services | CA | $26,665,848Large | 87.76 |
| Clara White MissionEIN 59-6002104 | Human Services | FL | $2,278,850Small | 86.84 |
| Claris HealthEIN 95-4806856 | Health | CA | $1,155,601Small | 85.87 |
| Clarke Schools for Hearing and SpeechEIN 04-2104008 | Education | MA | $11,678,628Mid-sized | 82.72 |
| Classic Wines AuctionEIN 20-1260228 | Human Services | OR | $3,217,257Small | 82.82 |
| Classroom, Inc.EIN 13-3666846 | Education | NY | $4,643,853Mid-sized | 87.65 |
| Clean WisconsinEIN 39-1413448 | Environment | WI | $1,905,696Small | 89.72 |
| Clearwater Camp FoundationEIN 43-2024465 | Human Services | WI | $890,698Small | 86.95 |
| Cleveland Leadership CenterEIN 34-1927317 | Education | OH | $1,646,527Small | 86.32 |
| Climate CentralEIN 26-1797336 | Environment | NJ | $9,872,125Mid-sized | 84.53 |
| Climate SolutionsEIN 91-1123302 | Environment | WA | $3,134,433Small | 82.66 |