| Catholic Charities Southwestern OhioEIN 31-0536968 | Human Services | OH | $16,836,807Large | 87.22 |
| Catholic Charities, Diocese of NorwichEIN 06-0646609 | Human Services | CT | $2,105,175Small | 80.10 |
| Catholic Community FoundationEIN 34-1908579 | Human Services | OH | $18,059,323Large | 80.25 |
| Catholic Education ArizonaEIN 86-0937587 | Education | AZ | $18,380,089Large | 83.46 |
| Catholic Health Initiatives Colorado FoundationEIN 84-0902211 | Health | CO | $24,601,571Large | 81.46 |
| Catholic Social Services of Southern NebraskaEIN 47-0751554 | Human Services | NE | $6,160,111Mid-sized | 86.04 |
| CatholicTVEIN 04-2395520 | Religion | MA | $9,283,767Mid-sized | 80.75 |
| CBMCEIN 36-2004402 | Religion | TN | $9,309,673Mid-sized | 83.97 |
| CEAPEIN 41-0990340 | Human Services | MN | $4,193,723Mid-sized | 85.73 |
| CEC ArtsLinkEIN 13-2531695 | International | NY | $724,948Small | 82.05 |
| Cedar Valley United WayEIN 42-0801846 | Community Development | IA | $2,470,131Small | 88.50 |
| Center for Arizona PolicyEIN 86-0618922 | Human and Civil Rights | AZ | $1,965,515Small | 88.30 |
| Center for Arms Control and Non-ProliferationEIN 04-2693322 | Human and Civil Rights | DC | $905,915Small | 85.56 |
| Center for Arts EducationEIN 13-3938080 | Education | NY | $2,749,501Small | 81.74 |
| Center for Arts-Inspired LearningEIN 34-1241756 | Education | OH | $1,786,799Small | 83.36 |
| Center for Child & Family ServicesEIN 54-0505893 | Human Services | VA | $1,647,899Small | 89.18 |
| Center for Children & Youth JusticeEIN 20-4457248 | Human and Civil Rights | WA | $2,216,576Small | 81.11 |
| Center for Climate and Energy SolutionsEIN 54-1892252 | Research and Public Policy | VA | $4,316,838Mid-sized | 84.09 |
| Center for Collaborative EducationEIN 04-3241676 | Education | MA | $4,694,075Mid-sized | 84.78 |
| Center for Community ChangeEIN 52-0888113 | Community Development | DC | $17,680,880Large | 88.05 |
| Center For Consumer FreedomEIN 26-0006579 | Human and Civil Rights | DC | $3,930,347Mid-sized | 86.10 |
| Center for Creative Land RecyclingEIN 94-3302410 | Environment | CA | $984,006Small | 89.40 |
| Center for EcoliteracyEIN 94-2911417 | Environment | CA | $2,386,398Small | 88.26 |
| Center for Economic and Policy ResearchEIN 52-2204029 | Research and Public Policy | DC | $1,990,467Small | 89.08 |
| Center for Education ReformEIN 52-1847187 | Education | DC | $2,366,966Small | 88.69 |
| Center for Energy Efficiency and Renewable TechnologiesEIN 68-0260751 | Environment | CA | $2,329,330Small | 81.32 |
| Center for Food SafetyEIN 52-2165893 | Research and Public Policy | DC | $4,380,584Mid-sized | 85.99 |
| Center for Great Neighborhoods of CovingtonEIN 61-0733046 | Community Development | KY | $1,454,120Small | 83.91 |
| Center for Hearing and CommunicationEIN 13-1624127 | Human Services | NY | $5,685,758Mid-sized | 86.20 |
| Center for Immigration StudiesEIN 52-1449368 | Research and Public Policy | DC | $2,816,435Small | 88.40 |
| Center for InquiryEIN 22-2306795 | Human and Civil Rights | DC | $4,833,092Mid-sized | 84.95 |
| Center for International PolicyEIN 52-1446207 | International | DC | $5,101,628Mid-sized | 88.46 |
| Center for Jewish HistoryEIN 13-3863344 | Arts, Culture, Humanities | NY | $8,554,129Mid-sized | 86.15 |
| Center for Leadership DevelopmentEIN 35-1389882 | Education | IN | $2,164,081Small | 84.98 |
| Center for Media and DemocracyEIN 39-1777402 | Arts, Culture, Humanities | WI | $1,843,241Small | 82.77 |
| Center for Planning ExcellenceEIN 20-3827040 | Community Development | LA | $1,719,044Small | 82.76 |
| Center for Public IntegrityEIN 54-1512177 | Research and Public Policy | DC | $5,208,118Mid-sized | 89.11 |
| Center for Science in the Public InterestEIN 23-7122879 | Research and Public Policy | DC | $12,565,933Mid-sized | 85.45 |
| Center for Strategic and Budgetary AssessmentsEIN 52-1930922 | Research and Public Policy | DC | $8,653,272Mid-sized | 84.06 |
| Center for Talent InnovationEIN 13-3730312 | Research and Public Policy | NY | $4,340,285Mid-sized | 88.16 |
| Center for Teaching QualityEIN 04-3606319 | Education | NC | $2,140,229Small | 84.11 |
| Center for the HomelessEIN 35-1768544 | Human Services | IN | $3,240,450Small | 85.36 |
| Center for the National InterestEIN 26-2117013 | Research and Public Policy | DC | $4,008,865Mid-sized | 89.04 |
| Center for the New EconomyEIN 66-0566096 | Research and Public Policy | PR | $2,308,832Small | 87.15 |
| Center for the Study of Social PolicyEIN 52-1254948 | Human Services | DC | $13,048,910Mid-sized | 89.42 |
| Center for Women & EnterpriseEIN 04-3256236 | Community Development | MA | $2,797,407Small | 84.58 |
| Center StageEIN 52-0780194 | Arts, Culture, Humanities | MD | $9,050,818Mid-sized | 86.65 |
| Centers for the Arts of Bonita SpringsEIN 65-0295085 | Arts, Culture, Humanities | FL | $2,634,919Small | 85.14 |
| Central American Medical OutreachEIN 34-1740695 | International | OH | $2,489,025Small | 86.05 |
| Central Asia InstituteEIN 51-0376237 | International | MT | $5,291,098Mid-sized | 84.66 |
| Central Coast Alliance United for A Sustainable EconomyEIN 77-0578864 | Human and Civil Rights | CA | $1,051,634Small | 88.85 |
| Central Florida YMCAEIN 59-0624430 | Human Services | FL | $59,588,094Large | 85.96 |
| Central Union MissionEIN 53-0218650 | Human Services | DC | $16,421,755Large | 89.86 |
| Cerebral PalsyEIN 39-0901265 | Health | WI | $6,080,335Mid-sized | 88.99 |
| Cerebral Palsy FoundationEIN 13-6093337 | Health | NY | $1,808,965Small | 82.51 |
| CETEIN 31-0560051 | Arts, Culture, Humanities | OH | $5,016,398Mid-sized | 84.20 |
| CFES Brilliant PathwaysEIN 22-3159630 | Education | NY | $3,564,584Mid-sized | 84.83 |
| Chai LifelineEIN 11-2940331 | Human Services | NY | $19,233,028Large | 86.18 |
| Challenged Athletes FoundationEIN 33-0739596 | Human Services | CA | $8,869,120Mid-sized | 84.16 |
| Challenged Child & FriendsEIN 58-1622732 | Education | GA | $2,311,777Small | 80.16 |