| Camp Boggy CreekEIN 59-3012889 | Health | FL | $5,974,701Mid-sized | 85.15 |
| Camp Courageous of IowaEIN 23-7210932 | Health | IA | $6,518,726Mid-sized | 88.75 |
| Camp Fire Green CountryEIN 73-0579231 | Human Services | OK | $1,165,647Small | 88.45 |
| Camp Fire National HeadquartersEIN 13-1623921 | Human Services | MO | $3,217,004Small | 80.63 |
| Camp For AllEIN 76-0404267 | Health | TX | $4,641,381Mid-sized | 89.53 |
| Camp KudzuEIN 58-2449646 | Health | GA | $1,860,091Small | 89.51 |
| Camp Nejeda FoundationEIN 22-0019138 | Health | NJ | $1,827,739Small | 83.64 |
| Campaign for College OpportunityEIN 20-0427622 | Education | CA | $1,675,237Small | 85.96 |
| Camphill Soltane FoundationEIN 02-0564982 | Education | PA | $2,286,377Small | 80.66 |
| Cancer Support Community Greater Cincinnati-Northern KentuckyEIN 31-1287785 | Health | OH | $1,105,185Small | 88.46 |
| Cancer Support Community Los AngelesEIN 33-0287070 | Health | CA | $1,350,425Small | 82.18 |
| Canine AssistantsEIN 58-1974410 | Animals | GA | $2,447,707Small | 82.18 |
| Canine Companions for IndependenceEIN 94-2494324 | Animals | CA | $26,185,688Large | 88.43 |
| Canine Partners For LifeEIN 23-2580658 | Animals | PA | $1,603,646Small | 83.52 |
| Canton Symphony OrchestraEIN 34-6533119 | Arts, Culture, Humanities | OH | $1,605,860Small | 89.06 |
| Canvasback Missions, Inc.EIN 93-0831904 | International | CA | $1,888,696Small | 82.50 |
| CAPA New HavenEIN 06-1625278 | Arts, Culture, Humanities | CT | $6,249,651Mid-sized | 88.90 |
| Cape Cod Commercial Fishermen's AllianceEIN 04-3138784 | Environment | MA | $2,000,667Small | 88.88 |
| Cape Eleuthera FoundationEIN 31-1591503 | Education | MA | $2,795,055Small | 89.62 |
| Cape Fear Botanical GardenEIN 56-1673281 | Environment | NC | $1,887,631Small | 84.64 |
| Capital Area Humane Society, MIEIN 38-1601542 | Animals | MI | $2,496,144Small | 89.92 |
| Capital Area United Way, MichiganEIN 38-1363572 | Community Development | MI | $3,844,560Mid-sized | 87.94 |
| Capital Humane SocietyEIN 47-0376622 | Animals | NE | $2,434,890Small | 86.89 |
| Capital IDEAEIN 74-2893041 | Human Services | TX | $4,483,755Mid-sized | 89.99 |
| Capital Public RadioEIN 68-0223271 | Arts, Culture, Humanities | CA | $10,465,669Mid-sized | 87.78 |
| Captain Planet FoundationEIN 58-1959421 | Environment | GA | $1,391,793Small | 89.96 |
| CaramoorEIN 13-5643627 | Arts, Culture, Humanities | NY | $7,027,427Mid-sized | 86.67 |
| CAREEIN 13-1685039 | International | GA | $581,648,006Large | 87.02 |
| Careers through Culinary Arts Program (C-CAP)EIN 13-3662917 | Human Services | NY | $6,225,489Mid-sized | 85.90 |
| Caring for CambodiaEIN 20-3645945 | Education | TX | $1,075,111Small | 87.81 |
| Caring Voice CoalitionEIN 26-0058446 | Health | VA | $87,769,321Large | 89.20 |
| CaringBridgeEIN 42-1529394 | Health | MN | $7,318,728Mid-sized | 81.08 |
| Caritas of AustinEIN 74-1909670 | Human Services | TX | $12,546,415Mid-sized | 87.34 |
| Carmel FoundationEIN 94-1225368 | Human Services | CA | $2,544,823Small | 82.50 |
| Carnegie Council for Ethics in International AffairsEIN 13-1573954 | International | NY | $3,528,670Mid-sized | 81.55 |
| Carnegie Endowment for International PeaceEIN 13-0552040 | International | DC | $36,544,639Large | 86.94 |
| Carnegie Institution for ScienceEIN 53-0196523 | Research and Public Policy | DC | $100,297,805Large | 87.74 |
| Carnegie Museums of PittsburghEIN 25-0965280 | Arts, Culture, Humanities | PA | $60,885,821Large | 86.59 |
| Carolina BalletEIN 56-1445383 | Arts, Culture, Humanities | NC | $5,871,426Mid-sized | 89.69 |
| Carolina Raptor CenterEIN 56-1349170 | Animals | NC | $1,346,881Small | 87.96 |
| Carpenter's ShelterEIN 54-1571849 | Human Services | VA | $2,133,586Small | 88.40 |
| Casa De AmigosEIN 75-1240087 | Human Services | TX | $995,709Small | 88.72 |
| Casa de Esperanza de Los NinosEIN 76-0105306 | Human Services | TX | $3,933,307Mid-sized | 89.53 |
| Casa de MarylandEIN 52-1372972 | Education | MD | $9,534,556Mid-sized | 83.76 |
| CASA of Los AngelesEIN 95-3890446 | Human Services | CA | $3,600,000Mid-sized | 80.49 |
| Casa TeresaEIN 95-3251986 | Human Services | CA | $2,588,883Small | 82.72 |
| Casas Por CristoEIN 74-2679881 | International | TX | $3,458,456Small | 82.51 |
| Cascade AIDS ProjectEIN 93-0903383 | Health | OR | $7,017,544Mid-sized | 86.00 |
| Casita MariaEIN 13-1623994 | Human Services | NY | $3,239,288Small | 88.21 |
| Cat Adoption TeamEIN 20-0773189 | Animals | OR | $1,840,044Small | 89.24 |
| CATCH Neighborhood HousingEIN 02-0433505 | Community Development | NH | $1,696,293Small | 88.23 |
| Catch-A-Dream FoundationEIN 20-0487728 | Health | MS | $873,893Small | 84.60 |
| Cathedral Arts ProjectEIN 59-3672453 | Human Services | FL | $1,546,620Small | 88.36 |
| Catholic Big Sisters & Big BrothersEIN 13-5564115 | Human Services | NY | $1,235,856Small | 87.63 |
| Catholic Charities Archdiocese of New OrleansEIN 72-0408911 | Human Services | LA | $25,374,533Large | 87.30 |
| Catholic Charities AtlantaEIN 58-1097003 | Human Services | GA | $5,894,054Mid-sized | 86.38 |
| Catholic Charities Diocese of ClevelandEIN 34-1318541 | Human Services | OH | $94,796,377Large | 86.67 |
| Catholic Charities of BaltimoreEIN 52-0591538 | Human Services | MD | $110,847,148Large | 87.17 |
| Catholic Charities of Santa Clara CountyEIN 94-2762269 | Human Services | CA | $35,534,021Large | 87.91 |
| Catholic Charities of the Archdiocese of OmahaEIN 47-0376612 | Human Services | NE | $5,110,419Mid-sized | 86.53 |