| Operation HOPEEIN 95-4378084 | Education | CA | $15,027,756Large | 87.82 |
| Operation NightwatchEIN 91-0964027 | Human Services | WA | $1,154,918Small | 87.82 |
| Orange County Museum of ArtEIN 95-1660847 | Arts, Culture, Humanities | CA | $2,605,178Small | 85.08 |
| Orange County United WayEIN 33-0047994 | Community Development | CA | $17,947,341Large | 89.73 |
| Orchestra of St. Luke'sEIN 51-0201839 | Arts, Culture, Humanities | NY | $7,749,571Mid-sized | 86.11 |
| Oregon Energy FundEIN 93-1029893 | Human Services | OR | $1,245,206Small | 89.18 |
| Oregon Shakespeare FestivalEIN 93-0407022 | Arts, Culture, Humanities | OR | $41,256,313Large | 87.08 |
| Oregon SymphonyEIN 93-0446527 | Arts, Culture, Humanities | OR | $18,547,539Large | 89.51 |
| Organic Consumers AssociationEIN 41-1908341 | Environment | MN | $3,495,920Small | 87.44 |
| Organic Farming Research FoundationEIN 77-0252545 | Research and Public Policy | CA | $871,992Small | 87.24 |
| Organization for Tropical StudiesEIN 56-2125831 | Education | NC | $8,180,616Mid-sized | 83.68 |
| Orlando Museum of ArtEIN 59-0910352 | Arts, Culture, Humanities | FL | $3,686,650Mid-sized | 85.17 |
| Orlando Philharmonic OrchestraEIN 59-3058884 | Arts, Culture, Humanities | FL | $5,112,662Mid-sized | 89.11 |
| Orlando Science CenterEIN 59-0896343 | Arts, Culture, Humanities | FL | $9,959,285Mid-sized | 89.48 |
| Orlando Union Rescue MissionEIN 59-1035082 | Human Services | FL | $5,899,987Mid-sized | 84.92 |
| Orphan HelpersEIN 54-1995429 | Religion | VA | $605,140Small | 80.16 |
| Oshkosh Area Community FoundationEIN 39-2034571 | Community Development | WI | $7,573,460Mid-sized | 86.28 |
| Oshkosh Area Humane SocietyEIN 39-1709813 | Animals | WI | $1,116,589Small | 86.10 |
| Our Daily Bread MinistriesEIN 38-1613981 | Religion | MI | $46,676,641Large | 89.50 |
| Our KidsEIN 58-1830327 | Human Services | TN | $1,502,257Small | 85.53 |
| Our Piece of the PieEIN 06-0939659 | Human Services | CT | $8,879,851Mid-sized | 88.22 |
| Out & Equal Workplace AdvocatesEIN 02-0681855 | Human and Civil Rights | CA | $5,530,425Mid-sized | 89.54 |
| Outdoor Discovery Center Macatawa GreenwayEIN 38-2461102 | Environment | MI | $2,992,451Small | 88.77 |
| Outdoors for All FoundationEIN 91-1085999 | Human Services | WA | $1,795,306Small | 85.25 |
| Outreach360EIN 58-2197227 | International | AZ | $1,334,211Small | 89.84 |
| OutRight Action InternationalEIN 94-3139952 | Human and Civil Rights | NY | $2,691,363Small | 88.00 |
| OutServe-SLDNEIN 52-1845000 | Human and Civil Rights | DC | $489,839Small | 86.77 |
| Overlook FoundationEIN 51-0194054 | Health | NJ | $6,419,341Mid-sized | 84.96 |
| Overtown Youth CenterEIN 65-1048896 | Education | FL | $3,579,226Mid-sized | 88.81 |
| Oxfam AmericaEIN 23-7069110 | International | MA | $91,570,741Large | 83.65 |
| Pacific Crest Trail AssociationEIN 33-0051202 | Environment | CA | $3,359,863Small | 81.60 |
| Pacific EnvironmentEIN 94-2628924 | Environment | CA | $1,330,701Small | 86.58 |
| Pacific Justice InstituteEIN 91-1823641 | Human and Civil Rights | CA | $2,058,162Small | 80.41 |
| Pacific Marine Mammal CenterEIN 95-3680896 | Animals | CA | $1,876,899Small | 87.87 |
| Pacific SymphonyEIN 95-3635496 | Arts, Culture, Humanities | CA | $20,980,482Large | 82.32 |
| PADS Lake CountyEIN 36-2948857 | Human Services | IL | $1,908,369Small | 89.02 |
| Page Education FoundationEIN 36-3605013 | Education | MN | $1,300,079Small | 88.72 |
| Palm Beach OperaEIN 59-1060864 | Arts, Culture, Humanities | FL | $4,633,253Mid-sized | 86.79 |
| Palmer Home for ChildrenEIN 64-0334999 | Human Services | MS | $5,942,324Mid-sized | 83.77 |
| Palo Alto Partners in EducationEIN 77-0186364 | Education | CA | $6,185,868Mid-sized | 88.98 |
| Pando InitiativeEIN 48-1093130 | Education | KS | $1,375,496Small | 89.21 |
| Panhandle-Plains Historical MuseumEIN 75-6019872 | Arts, Culture, Humanities | TX | $1,903,823Small | 82.91 |
| Pardes Institute of Jewish Studies, North AmericaEIN 22-2594099 | Education | NY | $4,631,629Mid-sized | 87.65 |
| Park Square Theatre CompanyEIN 41-1280683 | Arts, Culture, Humanities | MN | $3,602,045Mid-sized | 87.96 |
| Pastoral InstituteEIN 58-0647764 | Human Services | GA | $3,520,873Mid-sized | 83.13 |
| PATHEIN 91-1157127 | International | WA | $333,063,151Large | 89.08 |
| Pathways.orgEIN 52-2456469 | Health | IL | $3,272,387Small | 82.84 |
| Patrick Henry Family ServicesEIN 54-0660819 | Human Services | VA | $5,477,543Mid-sized | 81.00 |
| Paul Anderson Youth HomeEIN 58-6041868 | Human Services | GA | $2,117,159Small | 88.58 |
| Paul Taylor Dance FoundationEIN 13-2665475 | Arts, Culture, Humanities | NY | $9,680,646Mid-sized | 89.24 |
| Paul's PlaceEIN 52-1372359 | Human Services | MD | $3,287,117Small | 88.79 |
| PAVEEIN 39-1590212 | Education | WI | $1,583,805Small | 80.82 |
| PAWS/LAEIN 95-4178092 | Animals | CA | $1,224,056Small | 80.63 |
| Peabody Essex MuseumEIN 04-3157815 | Arts, Culture, Humanities | MA | $36,772,165Large | 87.61 |
| Peaceful Valley Donkey RescueEIN 77-0562800 | Animals | TX | $3,470,779Small | 81.36 |
| Pediatric Brain Tumor FoundationEIN 58-1966822 | Health | NC | $5,985,760Mid-sized | 80.76 |
| Pediatric Cancer Research FoundationEIN 95-3772528 | Health | CA | $2,492,062Small | 86.97 |
| Peninsula Humane Society & SPCAEIN 94-1243665 | Animals | CA | $12,522,099Mid-sized | 80.84 |
| Peninsula Jewish Community CenterEIN 94-3227262 | Human Services | CA | $18,227,062Large | 89.45 |
| Pennsylvania BalletEIN 23-1629970 | Arts, Culture, Humanities | PA | $14,070,730Large | 84.52 |