| Jewish Federation of St. LouisEIN 43-0652643 | Community Development | MO | $18,769,591Large | 91.74 |
| JOY FM RadioEIN 43-1793303 | Religion | MO | $6,201,501Mid-sized | 83.42 |
| Junior Achievement of Greater St. LouisEIN 43-0652112 | Education | MO | $3,534,388Mid-sized | 90.87 |
| Kansas City BalletEIN 43-6052680 | Arts, Culture, Humanities | MO | $10,326,107Mid-sized | 95.24 |
| Kansas City Repertory TheatreEIN 43-1168979 | Arts, Culture, Humanities | MO | $7,243,463Mid-sized | 85.33 |
| Kansas City Rescue MissionEIN 43-1287029 | Human Services | MO | $3,117,714Small | 92.39 |
| Kansas City Starlight TheatreEIN 44-0552079 | Arts, Culture, Humanities | MO | $20,852,373Large | 95.40 |
| Kansas City SymphonyEIN 43-1297475 | Arts, Culture, Humanities | MO | $16,520,157Large | 90.67 |
| Kauffman Center for the Performing ArtsEIN 43-1866550 | Arts, Culture, Humanities | MO | $21,566,408Large | 89.45 |
| Kids Across America FoundationEIN 43-1348373 | Human Services | MO | $5,528,517Mid-sized | 83.82 |
| Kilo Diabetes & Vascular Research FoundationEIN 23-7152540 | Health | MO | $332,850Small | 74.65 |
| Laumeier Sculpture ParkEIN 43-1131429 | Arts, Culture, Humanities | MO | $1,879,075Small | 73.48 |
| Legal Aid of Western MissouriEIN 43-0824638 | Human and Civil Rights | MO | $8,725,119Mid-sized | 85.86 |
| Lives Under Construction Boys RanchEIN 46-0368556 | Human Services | MO | $1,358,480Small | 78.47 |
| Loaves and Fishes for St. LouisEIN 43-1251264 | Human Services | MO | $1,905,288Small | 86.60 |
| Lutheran Bible TranslatorsEIN 95-2630437 | Religion | MO | $3,933,406Mid-sized | 93.26 |
| Lydia's HouseEIN 43-1699278 | Human Services | MO | $1,356,848Small | 94.18 |
| Lyric Opera of Kansas CityEIN 44-0626124 | Arts, Culture, Humanities | MO | $6,714,592Mid-sized | 89.96 |
| Make-A-Wish® Missouri & KansasEIN 43-1550697 | Health | MO | $5,144,874Mid-sized | 79.77 |
| Marian Middle SchoolEIN 43-1873629 | Education | MO | $1,735,400Small | 90.04 |
| Meds & Food for KidsEIN 20-1257910 | International | MO | $3,936,346Mid-sized | 100.00 |
| MERS Missouri Goodwill IndustriesEIN 43-0652657 | Human Services | MO | $161,570,313Large | 88.08 |
| Mexico Area Family YMCAEIN 43-1147430 | Human Services | MO | $1,236,978Small | 90.94 |
| Mid America Assistance CoalitionEIN 43-1186173 | Human Services | MO | $1,257,864Small | 82.29 |
| Missouri Botanical GardenEIN 43-0666759 | Environment | MO | $45,210,838Large | 87.76 |
| Missouri History MuseumEIN 43-0654866 | Arts, Culture, Humanities | MO | $21,586,472Large | 97.14 |
| National Council of the United States, Society of St. Vincent de PaulEIN 13-5562362 | Human Services | MO | $9,243,718Mid-sized | 82.00 |
| Nelson-Atkins Museum of ArtEIN 44-6012977 | Arts, Culture, Humanities | MO | $41,548,030Large | 88.06 |
| NewhouseEIN 43-0962293 | Human Services | MO | $2,051,211Small | 80.48 |
| Nine Network of Public MediaEIN 43-0685345 | Arts, Culture, Humanities | MO | $9,576,699Mid-sized | 88.20 |
| Nonprofit Leadership AllianceEIN 44-0546869 | Education | MO | $1,684,187Small | 76.44 |
| Noyes Home for ChildrenEIN 44-0563788 | Human Services | MO | $2,369,119Small | 80.79 |
| Nurses for Newborns EIN 43-1601329 | Human Services | MO | $4,296,133Mid-sized | 90.29 |
| Opera Theatre of Saint LouisEIN 43-0821958 | Arts, Culture, Humanities | MO | $10,222,016Mid-sized | 93.44 |
| Operation BreakthroughEIN 43-0971560 | Human Services | MO | $8,616,112Mid-sized | 95.72 |
| Operation Food SearchEIN 43-1241854 | Human Services | MO | $33,636,061Large | 94.03 |
| Optimist International FoundationEIN 23-7102928 | Education | MO | $1,513,808Small | 90.41 |
| Our Lady's InnEIN 43-1213751 | Human Services | MO | $2,584,254Small | 91.69 |
| Our Little HavenEIN 43-1567500 | Human Services | MO | $2,953,702Small | 95.16 |
| Outreach InternationalEIN 43-1164177 | International | MO | $3,571,376Mid-sized | 98.00 |
| Ozarks Food HarvestEIN 43-1426384 | Human Services | MO | $30,424,252Large | 97.46 |
| PKD FoundationEIN 43-1266906 | Health | MO | $6,120,336Mid-sized | 85.37 |
| Presbyterian Children's Homes and Services of MissouriEIN 43-1699263 | Human Services | MO | $8,536,097Mid-sized | 75.25 |
| Produce for Better Health FoundationEIN 51-0334897 | Research and Public Policy | MO | $2,263,416Small | 86.85 |
| Pujols Family FoundationEIN 20-2272546 | Human Services | MO | $860,588Small | 72.80 |
| reStartEIN 43-1349378 | Human Services | MO | $6,716,944Mid-sized | 90.58 |
| Ronald McDonald House Charities of Kansas CityEIN 43-1190760 | Health | MO | $4,464,880Mid-sized | 94.66 |
| Ronald McDonald House Charities of St. LouisEIN 43-1160478 | Health | MO | $4,156,934Mid-sized | 90.61 |
| Ronald McDonald House Charities of the OzarksEIN 43-1371143 | Health | MO | $1,512,833Small | 89.35 |
| Rose Brooks CenterEIN 51-0231573 | Human Services | MO | $6,361,265Mid-sized | 90.48 |
| Safe ConnectionsEIN 43-1077667 | Human Services | MO | $2,357,049Small | 90.14 |
| Saint Louis Symphony OrchestraEIN 43-0666769 | Arts, Culture, Humanities | MO | $30,010,463Large | 86.41 |
| Saint Louis Zoo AssociationEIN 43-1727309 | Animals | MO | $16,950,536Large | 91.13 |
| Scholarship Foundation of St. LouisEIN 43-6031234 | Education | MO | $6,200,105Mid-sized | 87.18 |
| Second Harvest Community Food BankEIN 43-1268319 | Human Services | MO | $10,909,604Mid-sized | 93.83 |
| Sheffield PlaceEIN 43-1532267 | Human Services | MO | $1,187,546Small | 100.00 |
| Shelterwood EIN 23-7362463 | Religion | MO | $5,554,488Mid-sized | 88.96 |
| Sherwood Forest CampEIN 43-0653401 | Human Services | MO | $1,738,056Small | 94.76 |
| Shiloh Christian Children's RanchEIN 43-1122941 | Human Services | MO | $1,982,671Small | 86.85 |
| Show-Me Christian Youth HomeEIN 43-1861323 | Human Services | MO | $2,080,172Small | 76.44 |