| The Children's Museum of MemphisEIN 62-1326890 | Arts, Culture, Humanities | TN | $2,879,765Small | 90.05 |
| The Children's PlaceEIN 51-0195216 | Human Services | MO | $3,128,396Small | 90.39 |
| The Children's Theatre of CincinnatiEIN 31-6026285 | Arts, Culture, Humanities | OH | $3,697,998Mid-sized | 82.83 |
| The Christian Broadcasting NetworkEIN 54-0678752 | Religion | VA | $319,708,060Large | 88.20 |
| The Christmas Box InternationalEIN 31-1617816 | Human Services | UT | $1,432,198Small | 85.19 |
| The ChristophersEIN 13-1809274 | Religion | NY | $1,565,431Small | 88.06 |
| The Circle of Friends for American VeteransEIN 54-1847890 | Human and Civil Rights | VA | $1,258,226Small | 23.84 |
| The Citizens Foundation, USAEIN 41-2046295 | International | IL | $9,005,147Mid-sized | 96.46 |
| The Claremont InstituteEIN 95-3443202 | Research and Public Policy | CA | $5,093,063Mid-sized | 83.87 |
| The Clay Center for the Arts & Sciences of West VirginiaEIN 55-0702401 | Arts, Culture, Humanities | WV | $10,281,996Mid-sized | 91.24 |
| The Cleveland FoundationEIN 34-0714588 | Community Development | OH | $104,350,367Large | 91.70 |
| The Cleveland Museum of ArtEIN 34-0714336 | Arts, Culture, Humanities | OH | $60,688,211Large | 88.50 |
| The Cleveland OrchestraEIN 34-0714468 | Arts, Culture, Humanities | OH | $55,320,592Large | 81.92 |
| The Cleveland Play HouseEIN 34-6515260 | Arts, Culture, Humanities | OH | $9,758,556Mid-sized | 88.22 |
| The Climate Reality ProjectEIN 87-0745629 | Environment | DC | $16,685,214Large | 88.37 |
| The Clinton FoundationEIN 31-1580204 | International | NY | $227,328,658Large | 92.40 |
| The Club for Boys, Rapid CityEIN 46-0277778 | Human Services | SD | $2,805,216Small | 76.43 |
| The Club FoundationEIN 52-1642692 | Education | VA | $646,372Small | 72.60 |
| The College Crusade of Rhode IslandEIN 22-3031765 | Education | RI | $5,119,803Mid-sized | 89.11 |
| The Colorado Center for the BlindEIN 74-2465141 | Human Services | CO | $2,780,286Small | 89.31 |
| The Colorado I Have A Dream FoundationEIN 74-2497109 | Education | CO | $1,453,441Small | 94.48 |
| The Columbus FoundationEIN 31-6044264 | Community Development | OH | $175,866,285Large | 95.05 |
| The Columbus MuseumEIN 58-6042894 | Arts, Culture, Humanities | GA | $3,185,682Small | 86.64 |
| The Committee for Hispanic Children and FamiliesEIN 11-2622003 | Human Services | NY | $4,491,509Mid-sized | 85.43 |
| The Committee for Missing ChildrenEIN 58-2215576 | Human and Civil Rights | GA | $901,041Small | 29.11 |
| The Community Foundation for Greater AtlantaEIN 58-1344646 | Community Development | GA | $121,717,288Large | 90.99 |
| The Community Foundation for Northeast FloridaEIN 59-6150746 | Community Development | FL | $41,921,959Large | 93.74 |
| The Community Foundation for Northern Virginia Inc.EIN 51-0232459 | Community Development | VA | $6,499,270Mid-sized | 92.47 |
| The Community Foundation of LouisvilleEIN 31-0997017 | Community Development | KY | $54,954,721Large | 96.46 |
| The Community Foundation of Sarasota CountyEIN 59-1956886 | Community Development | FL | $38,090,969Large | 91.34 |
| The Community Foundation of Western North CarolinaEIN 56-1223384 | Community Development | NC | $17,373,488Large | 90.07 |
| The Community Foundation Serving Richmond and Central VirginiaEIN 23-7009135 | Community Development | VA | $40,927,134Large | 92.25 |
| The Computer History MuseumEIN 77-0507525 | Arts, Culture, Humanities | CA | $12,796,532Mid-sized | 91.13 |
| The ConcilioEIN 75-1770140 | Human Services | TX | $1,787,285Small | 84.62 |
| The Concord CoalitionEIN 52-1787869 | Human and Civil Rights | VA | $1,538,793Small | 75.53 |
| The Connecticut ForumEIN 06-1343149 | Education | CT | $1,445,906Small | 80.07 |
| The Conservation AllianceEIN 94-3100867 | Environment | OR | $2,283,620Small | 87.20 |
| The Conservation FoundationEIN 23-7221206 | Environment | IL | $2,018,098Small | 93.62 |
| The Conservation FundEIN 52-1388917 | Environment | VA | $274,566,587Large | 96.46 |
| The Contemporary AustinEIN 74-1233816 | Arts, Culture, Humanities | TX | $6,467,043Mid-sized | 86.08 |
| The Cornelia de Lange Syndrome FoundationEIN 06-1057497 | Health | CT | $954,105Small | 92.38 |
| The CornerStone Rescue MissionEIN 36-3296431 | Human Services | SD | $3,513,304Mid-sized | 90.71 |
| The Council of State GovernmentsEIN 36-6000818 | Research and Public Policy | KY | $39,651,190Large | 80.51 |
| The Cousteau SocietyEIN 23-7337664 | Environment | VA | $2,104,614Small | 60.10 |
| The CradleEIN 36-2181994 | Human Services | IL | $6,967,977Mid-sized | 80.76 |
| The Creative CoalitionEIN 13-3517803 | Human and Civil Rights | NY | $1,738,283Small | 26.75 |
| The Crisis Center of Johnson CountyEIN 42-0955992 | Human Services | IA | $3,857,253Mid-sized | 89.24 |
| The Crystal Charity BallEIN 75-6035893 | Human Services | TX | $6,021,474Mid-sized | 86.56 |
| The CT ChallengeEIN 20-2777748 | Health | CT | $2,300,611Small | 78.64 |
| The Cummer Museum of Art & GardensEIN 59-2191587 | Arts, Culture, Humanities | FL | $4,800,748Mid-sized | 86.34 |
| The Dallas Arboretum and Botanical SocietyEIN 23-7375815 | Environment | TX | $24,493,663Large | 92.50 |
| The Dallas OperaEIN 75-6004746 | Arts, Culture, Humanities | TX | $18,462,712Large | 92.71 |
| The Damien CenterEIN 35-1711878 | Health | IN | $4,390,557Mid-sized | 91.14 |
| The David ProjectEIN 16-1616489 | Education | MA | $2,618,014Small | 78.88 |
| The David Sheldrick Wildlife Trust USAEIN 30-0224549 | Animals | CA | $5,248,475Mid-sized | 96.46 |
| The Dawson McAllister AssociationEIN 20-1198064 | Religion | TN | $2,193,321Small | 77.00 |
| The Dayton FoundationEIN 31-6027287 | Community Development | OH | $27,126,725Large | 83.65 |
| The Delaware Symphony OrchestraEIN 51-6017449 | Arts, Culture, Humanities | DE | $1,645,578Small | 87.75 |
| The Denver FoundationEIN 84-6048381 | Community Development | CO | $81,071,246Large | 90.42 |
| The Detroit Institute for ChildrenEIN 38-1359511 | Human Services | MI | $2,624,067Small | 85.57 |