| Capital Area United Way, MichiganEIN 38-1363572 | Community Development | MI | $3,844,560Mid-sized | 87.94 |
| Capital District Youth for ChristEIN 14-1433750 | Religion | NY | $1,483,762Small | 75.26 |
| Capital Humane SocietyEIN 47-0376622 | Animals | NE | $2,434,890Small | 86.89 |
| Capital IDEAEIN 74-2893041 | Human Services | TX | $4,483,755Mid-sized | 89.99 |
| Capital Public RadioEIN 68-0223271 | Arts, Culture, Humanities | CA | $10,465,669Mid-sized | 87.78 |
| Capital Research CenterEIN 52-1289734 | Research and Public Policy | DC | $2,844,996Small | 76.58 |
| Captain Planet FoundationEIN 58-1959421 | Environment | GA | $1,391,793Small | 89.96 |
| CaramoorEIN 13-5643627 | Arts, Culture, Humanities | NY | $7,027,427Mid-sized | 86.67 |
| CAREEIN 13-1685039 | International | GA | $581,648,006Large | 87.02 |
| Care and Share Food Bank for Southern ColoradoEIN 84-0731930 | Human Services | CO | $44,807,576Large | 94.28 |
| CARE House of Oakland CountyEIN 38-2305297 | Human Services | MI | $2,462,005Small | 90.43 |
| Care NetEIN 54-1382723 | Human and Civil Rights | VA | $4,354,027Mid-sized | 92.66 |
| Care RingEIN 56-0621073 | Health | NC | $3,191,733Small | 92.22 |
| Careers through Culinary Arts Program (C-CAP)EIN 13-3662917 | Human Services | NY | $6,225,489Mid-sized | 85.90 |
| CareNet Pregnancy Centers, AmarilloEIN 75-2195169 | Health | TX | $1,080,888Small | 91.79 |
| CareNet Pregnancy Services of DupageEIN 36-3154700 | Human Services | IL | $1,153,653Small | 76.13 |
| Caribbean Christian Centre for the DeafEIN 76-0763234 | International | MI | $1,358,173Small | 77.83 |
| Caridad CenterEIN 65-0149423 | Human Services | FL | $4,141,825Mid-sized | 99.06 |
| Caring for CambodiaEIN 20-3645945 | Education | TX | $1,075,111Small | 87.81 |
| Caring Voice CoalitionEIN 26-0058446 | Health | VA | $87,769,321Large | 89.20 |
| CaringBridgeEIN 42-1529394 | Health | MN | $7,318,728Mid-sized | 81.08 |
| CaringWorksEIN 56-2370081 | Human Services | GA | $6,142,050Mid-sized | 90.94 |
| CARITASEIN 54-1441917 | Human Services | VA | $3,295,879Small | 92.44 |
| Caritas of AustinEIN 74-1909670 | Human Services | TX | $12,546,415Mid-sized | 87.34 |
| Carmel FoundationEIN 94-1225368 | Human Services | CA | $2,544,823Small | 82.50 |
| Carnegie Council for Ethics in International AffairsEIN 13-1573954 | International | NY | $3,528,670Mid-sized | 81.55 |
| Carnegie Endowment for International PeaceEIN 13-0552040 | International | DC | $36,544,639Large | 86.94 |
| Carnegie Institution for ScienceEIN 53-0196523 | Research and Public Policy | DC | $100,297,805Large | 87.74 |
| Carnegie Museums of PittsburghEIN 25-0965280 | Arts, Culture, Humanities | PA | $60,885,821Large | 86.59 |
| Carolina BalletEIN 56-1445383 | Arts, Culture, Humanities | NC | $5,871,426Mid-sized | 89.69 |
| Carolina for KiberaEIN 56-2248495 | International | NC | $688,361Small | 90.05 |
| Carolina Raptor CenterEIN 56-1349170 | Animals | NC | $1,346,881Small | 87.96 |
| Carpenter's ShelterEIN 54-1571849 | Human Services | VA | $2,133,586Small | 88.40 |
| CARPLSEIN 36-3863573 | Human and Civil Rights | IL | $2,056,206Small | 90.17 |
| Carriage Town MinistriesEIN 38-1443378 | Human Services | MI | $2,568,726Small | 92.72 |
| Carson Scholars FundEIN 52-1851346 | Education | MD | $1,967,187Small | 90.00 |
| Cary Christian CenterEIN 64-0781589 | Human Services | MS | $914,934Small | 78.36 |
| Cary Institute of Ecosystem StudiesEIN 22-3232968 | Research and Public Policy | NY | $13,031,409Mid-sized | 94.32 |
| Casa De AmigosEIN 75-1240087 | Human Services | TX | $995,709Small | 88.72 |
| Casa de AmparoEIN 95-3315571 | Human Services | CA | $8,748,510Mid-sized | 96.46 |
| Casa de Esperanza de Los NinosEIN 76-0105306 | Human Services | TX | $3,933,307Mid-sized | 89.53 |
| Casa de MarylandEIN 52-1372972 | Education | MD | $9,534,556Mid-sized | 83.76 |
| CASA of Los AngelesEIN 95-3890446 | Human Services | CA | $3,600,000Mid-sized | 80.49 |
| CASA of the Pikes Peak RegionEIN 84-1115548 | Human Services | CO | $2,121,059Small | 90.78 |
| CASA of Travis CountyEIN 74-2369123 | Human Services | TX | $3,877,348Mid-sized | 91.53 |
| Casa TeresaEIN 95-3251986 | Human Services | CA | $2,588,883Small | 82.72 |
| Casas Por CristoEIN 74-2679881 | International | TX | $3,458,456Small | 82.51 |
| Cascade AIDS ProjectEIN 93-0903383 | Health | OR | $7,017,544Mid-sized | 86.00 |
| Casita MariaEIN 13-1623994 | Human Services | NY | $3,239,288Small | 88.21 |
| Casting for RecoveryEIN 03-0354382 | Health | MT | $1,529,836Small | 97.72 |
| Castleton Ranch Horse Rescue Inc.EIN 11-3731839 | Animals | CA | $1,611,503Small | 78.53 |
| Cat Adoption TeamEIN 20-0773189 | Animals | OR | $1,840,044Small | 89.24 |
| Cat Care SocietyEIN 84-0869447 | Animals | CO | $1,009,674Small | 91.82 |
| CATCH Neighborhood HousingEIN 02-0433505 | Community Development | NH | $1,696,293Small | 88.23 |
| Catch-A-Dream FoundationEIN 20-0487728 | Health | MS | $873,893Small | 84.60 |
| Cathedral Arts ProjectEIN 59-3672453 | Human Services | FL | $1,546,620Small | 88.36 |
| Cathedral KitchenEIN 22-3114500 | Human Services | NJ | $3,809,168Mid-sized | 98.23 |
| Catholic AnswersEIN 95-3754404 | Religion | CA | $7,475,369Mid-sized | 74.63 |
| Catholic Big Sisters & Big BrothersEIN 13-5564115 | Human Services | NY | $1,235,856Small | 87.63 |
| Catholic Charities Archdiocese of New OrleansEIN 72-0408911 | Human Services | LA | $25,374,533Large | 87.30 |