| Millennium Relief & Development ServicesEIN 76-0574590 | International | TX | $4,170,539Mid-sized | 73.52 |
| Millionair Club CharityEIN 91-0607513 | Human Services | WA | $6,538,256Mid-sized | 92.24 |
| Milwaukee Art MuseumEIN 39-0806316 | Arts, Culture, Humanities | WI | $19,236,271Large | 91.01 |
| Milwaukee BalletEIN 39-1134735 | Arts, Culture, Humanities | WI | $6,450,332Mid-sized | 89.90 |
| Milwaukee Jewish FederationEIN 39-0806312 | Community Development | WI | $25,533,075Large | 94.75 |
| Milwaukee Repertory TheaterEIN 39-0946025 | Arts, Culture, Humanities | WI | $11,651,807Mid-sized | 94.90 |
| Milwaukee Symphony OrchestraEIN 39-6023436 | Arts, Culture, Humanities | WI | $18,202,182Large | 84.79 |
| Mind & Life InstituteEIN 77-0284767 | Research and Public Policy | VA | $3,552,029Mid-sized | 89.22 |
| MIND Research InstituteEIN 33-0798804 | Education | CA | $29,110,497Large | 79.92 |
| Mingei International MuseumEIN 23-7433357 | Arts, Culture, Humanities | CA | $3,695,785Mid-sized | 79.45 |
| Ministry of CaringEIN 51-0209843 | Human Services | DE | $10,407,336Mid-sized | 94.95 |
| Ministry With CommunityEIN 38-2596981 | Human Services | MI | $1,675,939Small | 92.12 |
| Minneapolis Jewish FederationEIN 41-0693866 | Community Development | MN | $15,487,288Large | 86.47 |
| Minnesota Adult & Teen ChallengeEIN 41-1517351 | Health | MN | $33,498,517Large | 99.77 |
| Minnesota Center for Environmental AdvocacyEIN 23-7412105 | Environment | MN | $1,692,871Small | 93.82 |
| Minnesota Children's MuseumEIN 41-1354181 | Arts, Culture, Humanities | MN | $9,321,847Mid-sized | 88.69 |
| Minnesota Environmental FundEIN 41-1693030 | Environment | MN | $964,468Small | 86.29 |
| Minnesota Environmental PartnershipEIN 41-1986433 | Environment | MN | $651,587Small | 90.47 |
| Minnesota Historical SocietyEIN 41-0713907 | Arts, Culture, Humanities | MN | $60,451,270Large | 89.84 |
| Minnesota Indian Women's Resource CenterEIN 41-1500950 | Human Services | MN | $2,997,682Small | 72.33 |
| Minnesota Museum of American ArtEIN 41-0726138 | Arts, Culture, Humanities | MN | $1,469,148Small | 89.23 |
| Minnesota OperaEIN 41-0946789 | Arts, Culture, Humanities | MN | $11,190,288Mid-sized | 85.27 |
| Minnesota OrchestraEIN 41-0693875 | Arts, Culture, Humanities | MN | $33,889,255Large | 92.09 |
| Minnesota Public Radio | American Public MediaEIN 41-0953924 | Arts, Culture, Humanities | MN | $98,123,227Large | 92.68 |
| Minnesota State Fair FoundationEIN 41-2013696 | Arts, Culture, Humanities | MN | $1,855,342Small | 83.39 |
| Minnesota Zoo FoundationEIN 51-0147653 | Animals | MN | $3,820,920Mid-sized | 85.60 |
| Minnesotans Military Appreciation FundEIN 20-1935180 | Human Services | MN | $730,321Small | 65.32 |
| Minnetrista Gathering PlaceEIN 35-1628916 | Arts, Culture, Humanities | IN | $4,487,847Mid-sized | 80.09 |
| MinnPostEIN 26-0573427 | Arts, Culture, Humanities | MN | $1,628,555Small | 77.19 |
| Minority Corporate Counsel AssociationEIN 13-3920905 | Human and Civil Rights | DC | $2,948,017Small | 91.16 |
| Mint Theater CompanyEIN 13-3687725 | Arts, Culture, Humanities | NY | $1,894,443Small | 90.96 |
| Miracle FlightsEIN 88-0209952 | Health | NV | $3,726,507Mid-sized | 76.73 |
| Miracle FoundationEIN 74-2989580 | International | TX | $2,588,178Small | 92.54 |
| Miracle Hill MinistriesEIN 57-0425826 | Human Services | SC | $17,579,619Large | 89.75 |
| Miriam's KitchenEIN 52-1331552 | Human Services | DC | $4,421,295Mid-sized | 92.92 |
| MisaskimEIN 20-3957164 | Religion | NY | $1,776,940Small | 59.99 |
| MisericordiaEIN 36-2170153 | Human Services | IL | $68,981,056Large | 94.47 |
| Mises InstituteEIN 52-1263436 | Research and Public Policy | AL | $4,165,289Mid-sized | 94.70 |
| Mission Arlington/Mission MetroplexEIN 75-2354962 | Religion | TX | $3,860,708Mid-sized | 96.15 |
| Mission BlueEIN 26-1892969 | Environment | CA | $1,261,676Small | 80.39 |
| Mission EurasiaEIN 35-1835273 | Religion | IL | $4,262,417Mid-sized | 86.84 |
| Mission GranburyEIN 75-2766222 | Human Services | TX | $1,304,142Small | 85.84 |
| Mission Medical ClinicEIN 68-0506812 | Health | CO | $384,914Small | 74.88 |
| Mission of HopeEIN 62-1794508 | Human Services | TN | $2,958,234Small | 85.07 |
| Mission of MercyEIN 86-0704883 | Health | PA | $7,151,522Mid-sized | 93.89 |
| Mission PossibleEIN 34-1290940 | Religion | OH | $1,114,129Small | 84.18 |
| Mission to HaitiEIN 59-2173214 | International | FL | $667,035Small | 83.54 |
| Mission Waco Mission WorldEIN 74-2605621 | Religion | TX | $2,644,683Small | 98.01 |
| Mission Without BordersEIN 77-0292572 | International | CA | $1,198,470Small | 81.84 |
| Mission YearEIN 23-3005514 | Religion | IL | $735,526Small | 74.05 |
| Mission: HopeEIN 64-0866959 | International | GA | $2,410,206Small | 93.89 |
| Missionary Athletes InternationalEIN 33-0017152 | Religion | NC | $3,442,558Small | 83.18 |
| Missionary Aviation Repair CenterEIN 92-0032812 | Religion | AK | $2,511,792Small | 75.64 |
| Missionary Flights InternationalEIN 23-7199063 | Religion | FL | $4,326,147Mid-sized | 74.94 |
| Missionary Maintenance Service AviationEIN 31-0919027 | Religion | OH | $1,854,255Small | 81.53 |
| Mississippi Center for JusticeEIN 13-4203234 | Human and Civil Rights | MS | $3,606,434Mid-sized | 86.39 |
| Mississippi Children's MuseumEIN 64-0850010 | Arts, Culture, Humanities | MS | $3,541,158Mid-sized | 97.17 |
| Missoula Food BankEIN 81-0414143 | Human Services | MT | $4,608,782Mid-sized | 93.32 |
| Missouri Botanical GardenEIN 43-0666759 | Environment | MO | $45,210,838Large | 87.76 |
| Missouri History MuseumEIN 43-0654866 | Arts, Culture, Humanities | MO | $21,586,472Large | 97.14 |