| All Classical PortlandEIN 93-1042868 | Arts, Culture, Humanities | OR | $3,780,565Mid-sized | 92.79 |
| All Faiths Food BankEIN 65-0115814 | Human Services | FL | $20,387,573Large | 93.32 |
| All God's ChildrenEIN 38-2992649 | International | IL | $1,413,690Small | 96.46 |
| All Hands and Hearts Smart ResponseEIN 20-3414952 | Human Services | MA | $6,086,763Mid-sized | 98.23 |
| All Our KinEIN 06-1539280 | Human Services | CT | $3,609,613Mid-sized | 96.42 |
| All Stars Helping KidsEIN 77-0325111 | Education | CA | $1,910,079Small | 93.26 |
| Allen Community OutreachEIN 75-1986190 | Human Services | TX | $2,191,065Small | 95.43 |
| Allen County SPCAEIN 35-6042135 | Animals | IN | $1,302,736Small | 91.88 |
| Alley Cat AlliesEIN 52-1742079 | Animals | MD | $10,182,939Mid-sized | 93.98 |
| Alley TheatreEIN 74-1143076 | Arts, Culture, Humanities | TX | $20,708,905Large | 92.13 |
| Alliance For ChildrenEIN 75-2363035 | Human Services | TX | $4,387,651Mid-sized | 94.10 |
| Alliance for Children's RightsEIN 95-4358213 | Human Services | CA | $5,808,946Mid-sized | 96.47 |
| Alliance for JusticeEIN 52-1009973 | Human and Civil Rights | DC | $5,029,169Mid-sized | 95.83 |
| Alliance For The Great LakesEIN 23-7104524 | Environment | IL | $3,549,306Mid-sized | 97.72 |
| Alliance of Resident Theatres/New YorkEIN 13-2768583 | Arts, Culture, Humanities | NY | $4,115,637Mid-sized | 91.58 |
| Alpha-1 FoundationEIN 65-0585415 | Health | FL | $9,757,837Mid-sized | 97.13 |
| ALS Therapy Development InstituteEIN 04-3462719 | Health | MA | $12,533,202Mid-sized | 91.93 |
| Alzheimer's Family CenterEIN 95-3463975 | Human Services | CA | $4,400,117Mid-sized | 93.36 |
| Alzheimer's Foundation of AmericaEIN 91-1792864 | Health | NY | $6,562,695Mid-sized | 95.73 |
| AmaraEIN 91-0577487 | Human Services | WA | $3,424,856Small | 92.08 |
| Amazima MinistriesEIN 61-1555718 | International | TN | $2,726,430Small | 96.92 |
| Amazon Conservation AssociationEIN 52-2211305 | Environment | DC | $5,038,940Mid-sized | 93.33 |
| Amazon Conservation TeamEIN 54-1915987 | Environment | VA | $6,486,299Mid-sized | 99.06 |
| American Academy of Arts and SciencesEIN 04-2103651 | Research and Public Policy | MA | $11,527,301Mid-sized | 91.00 |
| American Associates, Ben-Gurion University of the NegevEIN 23-7270753 | Education | NY | $47,792,268Large | 95.94 |
| American Autoimmune Related Diseases AssociationEIN 38-3027574 | Health | MI | $945,382Small | 98.45 |
| American Battlefield TrustEIN 54-1426643 | Arts, Culture, Humanities | DC | $17,884,556Large | 96.94 |
| American Bird ConservancyEIN 52-1501259 | Animals | VA | $12,830,927Mid-sized | 91.41 |
| American Civil Liberties Union FoundationEIN 13-6213516 | Human and Civil Rights | NY | $115,464,165Large | 96.66 |
| American Committee for Shaare Zedek Medical Center In JerusalemEIN 13-5645878 | Health | NY | $20,966,439Large | 94.74 |
| American Committee for the Weizmann Institute of ScienceEIN 13-1623886 | Health | NY | $83,439,000Large | 90.96 |
| American Council for an Energy-Efficient Economy EIN 94-2711707 | Research and Public Policy | DC | $9,400,072Mid-sized | 95.43 |
| American Council on GermanyEIN 13-1889074 | International | NY | $1,962,779Small | 93.12 |
| American Eagle FoundationEIN 58-1652023 | Animals | TN | $1,807,117Small | 100.00 |
| American Family AssociationEIN 64-0607275 | Human and Civil Rights | MS | $18,860,780Large | 90.91 |
| American Federation for Aging ResearchEIN 13-3045282 | Health | NY | $5,980,117Mid-sized | 92.92 |
| American Forest FoundationEIN 52-1235124 | Environment | DC | $13,062,939Mid-sized | 96.39 |
| American Foundation for Surgery of the HandEIN 74-2428242 | Health | IL | $1,663,447Small | 90.87 |
| American Friends of Meir PanimEIN 20-1582478 | Human Services | NY | $5,126,089Mid-sized | 92.41 |
| American Friends of Migdal OhrEIN 13-3389558 | Human Services | NY | $5,992,863Mid-sized | 94.44 |
| American Friends of NishmatEIN 04-3106173 | Education | NY | $3,613,549Mid-sized | 92.22 |
| American Friends of the Episcopal Diocese of JerusalemEIN 59-6155008 | International | CT | $1,547,219Small | 95.73 |
| American Friends of the LouvreEIN 52-2376786 | Arts, Culture, Humanities | NY | $4,755,697Mid-sized | 92.02 |
| American Friends of The Tel Aviv UniversityEIN 13-1996126 | Education | NY | $36,078,234Large | 93.25 |
| American Friends of Yad EliezerEIN 11-3459952 | Human Services | NJ | $41,944,264Large | 94.69 |
| American Himalayan FoundationEIN 94-2951480 | International | CA | $5,218,592Mid-sized | 95.06 |
| American HumaneEIN 84-0432950 | Animals | DC | $15,536,919Large | 90.25 |
| American Humanist AssociationEIN 94-6168317 | Human and Civil Rights | DC | $2,295,879Small | 93.41 |
| American Immigration CouncilEIN 52-1549711 | Human and Civil Rights | DC | $5,483,109Mid-sized | 94.52 |
| American India FoundationEIN 13-4159765 | International | NY | $7,577,120Mid-sized | 91.04 |
| American Indian ServicesEIN 87-0477049 | Education | UT | $2,559,455Small | 90.91 |
| American Italian Cancer FoundationEIN 13-3035711 | Health | NY | $1,688,237Small | 91.63 |
| American Jewish Joint Distribution CommitteeEIN 13-1656634 | International | NY | $317,102,196Large | 96.37 |
| American Kennel Club Canine Health FoundationEIN 13-3813813 | Animals | NC | $3,097,717Small | 92.32 |
| American Museum of Natural HistoryEIN 13-6162659 | Arts, Culture, Humanities | NY | $214,025,292Large | 90.52 |
| American Nicaraguan FoundationEIN 65-0326517 | International | FL | $107,910,005Large | 97.44 |
| American Nonsmokers' Rights FoundationEIN 94-2922136 | Human and Civil Rights | CA | $2,848,886Small | 92.13 |
| American Refugee CommitteeEIN 36-3241033 | International | MN | $45,843,947Large | 96.46 |
| American Relief Agency for the Horn of Africa (ARAHA)EIN 41-1989714 | International | MN | $6,168,900Mid-sized | 92.74 |
| American Sexual Health AssociationEIN 94-2494435 | Human and Civil Rights | NC | $2,166,882Small | 91.93 |