| World Missionary PressEIN 35-1076405 | Religion | IN | $4,631,966Mid-sized | 91.39 |
| World NeighborsEIN 73-0707328 | International | OK | $3,484,562Small | 90.97 |
| World OrphansEIN 33-0571309 | International | CO | $3,179,482Small | 93.91 |
| World Pediatric ProjectEIN 54-1953305 | International | VA | $8,680,295Mid-sized | 91.00 |
| World ReliefEIN 23-6393344 | International | MD | $76,751,245Large | 91.20 |
| World Resources InstituteEIN 52-1257057 | Environment | DC | $94,564,842Large | 95.47 |
| Wounded Warriors Family SupportEIN 20-1407520 | Human Services | NE | $3,444,719Small | 94.11 |
| WVIA Public MediaEIN 23-1663603 | Arts, Culture, Humanities | PA | $31,292,986Large | 90.71 |
| WXXI Public Broadcasting CouncilEIN 16-0838086 | Arts, Culture, Humanities | NY | $12,417,898Mid-sized | 91.98 |
| Wyman CenterEIN 43-0653263 | Human Services | MO | $7,965,727Mid-sized | 93.91 |
| Wyoming Outdoor CouncilEIN 83-0259411 | Environment | WY | $1,232,541Small | 90.39 |
| Xerces Society for Invertebrate ConservationEIN 51-0175253 | Animals | OR | $3,906,555Mid-sized | 93.04 |
| Yale-China AssociationEIN 06-0646971 | International | CT | $1,890,229Small | 92.22 |
| Yamhill Community Action PartnershipEIN 93-0758732 | Human Services | OR | $6,642,102Mid-sized | 95.47 |
| Yavapai Big Brothers Big SistersEIN 86-0278776 | Human Services | AZ | $1,346,504Small | 92.10 |
| Year UpEIN 04-3534407 | Education | MA | $126,205,361Large | 90.18 |
| Yellowstone ForeverEIN 47-5427975 | Environment | WY | $17,497,778Large | 90.63 |
| Yellowstone to Yukon Conservation InitiativeEIN 81-0535303 | Environment | MT | $1,719,870Small | 92.74 |
| Yerba Buena Center for the ArtsEIN 94-3042571 | Arts, Culture, Humanities | CA | $15,060,479Large | 92.91 |
| YIVO Institute for Jewish ResearchEIN 13-1641082 | Arts, Culture, Humanities | NY | $4,795,588Mid-sized | 94.12 |
| YMCA of DeKalb CountyEIN 35-0868958 | Human Services | IN | $2,728,999Small | 92.02 |
| YMCA of Greater CharlotteEIN 56-1045299 | Human Services | NC | $87,362,021Large | 91.65 |
| YMCA of Greater Des MoinesEIN 42-0680438 | Human Services | IA | $24,791,877Large | 90.55 |
| YMCA of Greater Grand RapidsEIN 38-1358058 | Human Services | MI | $32,974,563Large | 93.51 |
| YMCA of Greater HoustonEIN 74-1109737 | Human Services | TX | $131,905,393Large | 90.26 |
| YMCA of Greater IndianapolisEIN 35-0868211 | Human Services | IN | $58,412,976Large | 94.34 |
| YMCA of Greater NashuaEIN 02-0222250 | Human Services | NH | $11,407,676Mid-sized | 93.32 |
| YMCA of Greater New YorkEIN 13-1624228 | Human Services | NY | $190,793,573Large | 93.31 |
| YMCA of Greater OmahaEIN 47-0376586 | Human Services | NE | $20,216,069Large | 93.91 |
| YMCA of Greater RochesterEIN 16-0743242 | Human Services | NY | $47,133,041Large | 91.42 |
| YMCA of Greater SeattleEIN 91-0482710 | Human Services | WA | $92,328,628Large | 96.15 |
| YMCA of Greater St. PetersburgEIN 59-0624468 | Human Services | FL | $13,559,665Large | 92.28 |
| YMCA of HonoluluEIN 99-0073533 | Human Services | HI | $28,641,629Large | 91.90 |
| YMCA of Metropolitan AtlantaEIN 58-0566253 | Human Services | GA | $106,169,583Large | 93.61 |
| YMCA of Metropolitan DallasEIN 75-0800696 | Human Services | TX | $58,010,719Large | 93.93 |
| YMCA of Metropolitan Los AngelesEIN 95-1644052 | Human Services | CA | $92,647,202Large | 93.13 |
| YMCA of Orange CountyEIN 95-1644055 | Human Services | CA | $41,178,500Large | 92.23 |
| YMCA of San Diego CountyEIN 95-2039198 | Human Services | CA | $179,969,000Large | 93.64 |
| YMCA of South Palm Beach CountyEIN 59-1416281 | Human Services | FL | $11,575,137Mid-sized | 91.27 |
| YMCA of the Fox CitiesEIN 39-0806191 | Human Services | WI | $24,652,066Large | 93.42 |
| YMCA of the Pikes Peak RegionEIN 84-0404266 | Human Services | CO | $27,030,879Large | 97.92 |
| YMCA of the RockiesEIN 84-0404913 | Human Services | CO | $35,505,449Large | 91.30 |
| YMCA of the SuncoastEIN 59-0810731 | Human Services | FL | $26,612,638Large | 95.40 |
| Young America's FoundationEIN 23-7042029 | Human and Civil Rights | VA | $23,732,711Large | 91.35 |
| Young LifeEIN 84-0385934 | Religion | CO | $327,920,020Large | 95.46 |
| Young Women's Preparatory NetworkEIN 47-0902114 | Education | TX | $2,770,254Small | 90.60 |
| Youth & Opportunity UnitedEIN 36-2734966 | Human Services | IL | $4,613,043Mid-sized | 96.06 |
| Youth Emergency ServicesEIN 47-0586898 | Human Services | NE | $1,870,270Small | 90.28 |
| Youth FirstEIN 35-2050168 | Human Services | IN | $3,479,595Small | 91.03 |
| Youth for Christ InternationalEIN 84-1188718 | Religion | CO | $4,793,915Mid-sized | 93.84 |
| Youth For TomorrowEIN 52-1342268 | Human Services | VA | $23,989,772Large | 90.58 |
| Youth HavenEIN 38-1882052 | Human Services | MI | $2,019,577Small | 95.67 |
| Youth Haven, FloridaEIN 23-7065187 | Human Services | FL | $3,685,981Mid-sized | 92.20 |
| Youth Law CenterEIN 94-1715280 | Human and Civil Rights | CA | $2,596,075Small | 90.04 |
| YWCA Cass ClayEIN 45-0226435 | Human Services | ND | $3,692,778Mid-sized | 90.10 |
| YWCA Evanston/North ShoreEIN 36-2193618 | Human Services | IL | $4,620,823Mid-sized | 92.02 |
| YWCA of San Diego CountyEIN 95-1661119 | Human Services | CA | $4,343,785Mid-sized | 93.37 |
| YWCA RichmondEIN 54-0506493 | Human Services | VA | $3,622,610Mid-sized | 99.29 |
| YWCA USAEIN 13-1624103 | Human Services | DC | $6,954,429Mid-sized | 94.51 |
| YWCA UtahEIN 87-0212467 | Human Services | UT | $6,290,573Mid-sized | 100.00 |