| Mark Wahlberg Youth FoundationEIN 04-3567369 | Education | MA | $1,573,707Small | 92.22 |
| Martha's Vineyard MuseumEIN 04-2160642 | Arts, Culture, Humanities | MA | $2,030,611Small | 73.37 |
| Mass Mentoring PartnershipEIN 22-3207958 | Human Services | MA | $2,420,195Small | 87.97 |
| MASS MoCAEIN 04-3113688 | Arts, Culture, Humanities | MA | $14,296,459Large | 79.41 |
| Massachusetts Audubon SocietyEIN 04-2104702 | Environment | MA | $29,467,469Large | 95.33 |
| Massachusetts Coalition for the HomelessEIN 22-2599662 | Human Services | MA | $3,788,528Mid-sized | 91.02 |
| Massachusetts Down Syndrome CongressEIN 22-2596246 | Health | MA | $1,509,177Small | 89.75 |
| Massachusetts Horticultural SocietyEIN 04-2104714 | Environment | MA | $1,690,583Small | 83.57 |
| Massachusetts Immigrant and Refugee Advocacy CoalitionEIN 22-3115048 | Human and Civil Rights | MA | $1,949,092Small | 86.25 |
| MassBioEdEIN 22-3799632 | Education | MA | $1,302,935Small | 87.92 |
| MassINCEIN 04-3271457 | Research and Public Policy | MA | $1,950,185Small | 83.15 |
| MENTOR/National Mentoring PartnershipEIN 52-1674088 | Human Services | MA | $6,787,437Mid-sized | 88.76 |
| Merrimack Valley Habitat for HumanityEIN 22-2672831 | Community Development | MA | $3,552,102Mid-sized | 89.22 |
| More Than WordsEIN 04-2784985 | Human Services | MA | $4,031,601Mid-sized | 90.58 |
| Morgan Memorial Goodwill IndustriesEIN 04-2106765 | Human Services | MA | $26,744,337Large | 86.46 |
| Mother Caroline Academy & Education CenterEIN 04-3163180 | Education | MA | $2,529,195Small | 85.11 |
| MSPCA-AngellEIN 04-2103597 | Animals | MA | $64,880,058Large | 92.20 |
| Museum of African American HistoryEIN 04-2429556 | Arts, Culture, Humanities | MA | $2,130,789Small | 73.24 |
| Museum of Fine Arts, BostonEIN 04-2103607 | Arts, Culture, Humanities | MA | $116,703,506Large | 85.68 |
| Museum of ScienceEIN 04-2103916 | Arts, Culture, Humanities | MA | $62,392,418Large | 87.76 |
| Mustard Seed CommunitiesEIN 58-1657207 | International | MA | $4,780,213Mid-sized | 98.23 |
| My Brother's KeeperEIN 04-3088412 | Human Services | MA | $4,044,691Mid-sized | 91.02 |
| Naismith Memorial Basketball Hall of FameEIN 04-6128892 | Arts, Culture, Humanities | MA | $10,289,678Mid-sized | 88.18 |
| Nantucket AtheneumEIN 04-2104412 | Arts, Culture, Humanities | MA | $2,737,637Small | 88.11 |
| Nantucket Boys & Girls ClubEIN 04-6114678 | Human Services | MA | $2,259,695Small | 90.74 |
| Nantucket Community SailingEIN 04-3252612 | Human Services | MA | $1,239,796Small | 92.12 |
| Nantucket Historical AssociationEIN 04-6003451 | Arts, Culture, Humanities | MA | $5,456,879Mid-sized | 84.34 |
| National Braille PressEIN 04-2104740 | Human Services | MA | $4,055,854Mid-sized | 79.76 |
| National Brain Tumor SocietyEIN 04-3068130 | Health | MA | $8,536,282Mid-sized | 77.82 |
| National Consumer Law CenterEIN 04-2488502 | Human and Civil Rights | MA | $8,365,127Mid-sized | 90.64 |
| National Yiddish Book CenterEIN 04-2708878 | Arts, Culture, Humanities | MA | $5,587,913Mid-sized | 82.91 |
| Nativity School of WorcesterEIN 03-0385377 | Education | MA | $1,580,928Small | 86.73 |
| NEADS Inc.EIN 23-7281887 | Animals | MA | $2,572,503Small | 94.27 |
| Neuroendocrine Tumor Research FoundationEIN 20-1945347 | Health | MA | $6,307,127Mid-sized | 97.17 |
| New Economy CoalitionEIN 03-0278626 | Research and Public Policy | MA | $1,317,133Small | 83.34 |
| New England Anti-Vivisection SocietyEIN 04-2104756 | Animals | MA | $1,211,547Small | 96.33 |
| New England Center and Home for VeteransEIN 04-3007211 | Human Services | MA | $9,212,479Mid-sized | 82.20 |
| New England Forestry FoundationEIN 04-2024022 | Environment | MA | $2,723,042Small | 89.97 |
| New England Foundation for the ArtsEIN 04-2593591 | Arts, Culture, Humanities | MA | $7,833,787Mid-sized | 95.04 |
| New England Historic Genealogical SocietyEIN 04-2104757 | Arts, Culture, Humanities | MA | $10,759,248Mid-sized | 87.92 |
| New England Paralyzed Veterans of AmericaEIN 04-6112881 | Human and Civil Rights | MA | $354,317Small | 68.13 |
| New England Wild Flower SocietyEIN 04-2104768 | Environment | MA | $2,639,084Small | 89.30 |
| New England Wildlife CenterEIN 04-2907561 | Animals | MA | $1,566,100Small | 91.78 |
| New ProfitEIN 04-3396766 | Education | MA | $25,800,571Large | 88.22 |
| Northampton Survival CenterEIN 04-2774166 | Human Services | MA | $2,120,033Small | 85.59 |
| Northeast Sustainable Energy AssociationEIN 23-7437161 | Environment | MA | $1,399,599Small | 74.96 |
| Ocean AllianceEIN 22-2573677 | Animals | MA | $765,223Small | 75.38 |
| Old Dartmouth Historical Society/New Bedford Whaling MuseumEIN 04-2104805 | Arts, Culture, Humanities | MA | $4,527,585Mid-sized | 93.25 |
| Oldways Preservation TrustEIN 04-3031978 | Research and Public Policy | MA | $2,135,083Small | 85.00 |
| On The RiseEIN 04-3290689 | Human Services | MA | $1,227,796Small | 89.22 |
| One FamilyEIN 54-2076936 | Human Services | MA | $1,493,655Small | 88.22 |
| Oxfam AmericaEIN 23-7069110 | International | MA | $91,570,741Large | 83.65 |
| Partners In HealthEIN 04-3567502 | International | MA | $145,464,654Large | 90.94 |
| Pathfinder InternationalEIN 53-0235320 | International | MA | $166,643,317Large | 90.91 |
| Peabody Essex MuseumEIN 04-3157815 | Arts, Culture, Humanities | MA | $36,772,165Large | 87.61 |
| Peace Development FundEIN 04-2738794 | International | MA | $3,242,376Small | 95.47 |
| Peace FirstEIN 04-3323467 | Human Services | MA | $1,722,426Small | 79.58 |
| Perkins School for the BlindEIN 04-2103616 | Education | MA | $69,957,149Large | 86.76 |
| Phillips Brook House AssociationEIN 04-6046123 | Community Development | MA | $3,011,296Small | 89.37 |
| Physician Health ServicesEIN 22-3234975 | Health | MA | $1,721,046Small | 86.24 |