| The Loft Literary CenterEIN 41-1297735 | Arts, Culture, Humanities | MN | $2,229,735Small | 84.75 |
| The Lord's PlaceEIN 59-2240502 | Human Services | FL | $7,433,411Mid-sized | 95.60 |
| The Los Angeles ConservancyEIN 95-3273046 | Arts, Culture, Humanities | CA | $2,409,119Small | 91.19 |
| The Los Angeles PhilharmonicEIN 95-1696734 | Arts, Culture, Humanities | CA | $130,412,242Large | 93.73 |
| The LPGA FoundationEIN 59-3085528 | Human Services | FL | $5,469,752Mid-sized | 83.77 |
| The Luke CommissionEIN 20-8635797 | International | ID | $5,038,554Mid-sized | 84.34 |
| The Luke SocietyEIN 84-0563440 | International | SD | $2,715,824Small | 79.40 |
| The Lustgarten Foundation for Pancreatic Cancer ResearchEIN 31-1611837 | Health | NY | $22,729,922Large | 100.00 |
| The Lyford Cay FoundationEIN 23-7025275 | Education | NY | $2,744,466Small | 85.36 |
| The MacDowell ColonyEIN 13-1592242 | Arts, Culture, Humanities | NH | $4,178,835Mid-sized | 81.05 |
| The Mailbox ClubEIN 23-7229445 | Religion | GA | $3,215,222Small | 93.91 |
| The Maine Children's Home for Little WanderersEIN 01-0267392 | Human Services | ME | $2,473,057Small | 92.02 |
| The Marfan FoundationEIN 52-1265361 | Health | NY | $4,465,668Mid-sized | 91.83 |
| The Marin Humane SocietyEIN 94-1156562 | Animals | CA | $8,260,861Mid-sized | 96.31 |
| The Marine Mammal CenterEIN 51-0144434 | Animals | CA | $10,612,857Mid-sized | 95.00 |
| The Mariners' MuseumEIN 54-0541801 | Arts, Culture, Humanities | VA | $10,573,622Mid-sized | 93.91 |
| The Marion InstituteEIN 04-3206583 | Environment | MA | $1,546,652Small | 78.69 |
| The Mark Twain House & MuseumEIN 06-0685118 | Arts, Culture, Humanities | CT | $3,033,651Small | 81.04 |
| The Marshall Legacy InstituteEIN 54-1853093 | International | VA | $1,715,975Small | 84.45 |
| The Maryland SPCAEIN 52-6001558 | Animals | MD | $6,592,967Mid-sized | 95.12 |
| The Maryland Symphony OrchestraEIN 52-1259358 | Arts, Culture, Humanities | MD | $1,569,658Small | 75.80 |
| The Massachusetts Historical SocietyEIN 04-2108374 | Arts, Culture, Humanities | MA | $6,102,179Mid-sized | 83.10 |
| The McGaw YMCAEIN 36-2169194 | Human Services | IL | $17,470,946Large | 89.81 |
| The Mentoring AllianceEIN 75-2541408 | Human Services | TX | $3,092,339Small | 86.27 |
| The Metropolitan Opera GuildEIN 13-1681983 | Arts, Culture, Humanities | NY | $11,808,977Mid-sized | 83.84 |
| The Middle East Media Research InstituteEIN 52-2068483 | International | DC | $5,903,271Mid-sized | 89.74 |
| The Midnight MissionEIN 95-1691293 | Human Services | CA | $9,508,855Mid-sized | 94.78 |
| The Miller Center FoundationEIN 54-1420895 | Research and Public Policy | VA | $2,724,275Small | 74.87 |
| The Mind TrustEIN 20-4560286 | Education | IN | $6,929,027Mid-sized | 92.22 |
| The Minneapolis FoundationEIN 41-6029402 | Community Development | MN | $70,849,060Large | 94.48 |
| The Minneapolis Institute of ArtsEIN 41-0693915 | Arts, Culture, Humanities | MN | $41,681,111Large | 92.05 |
| The Mint MuseumsEIN 56-0670666 | Arts, Culture, Humanities | NC | $10,388,083Mid-sized | 91.95 |
| The MissionEIN 68-0280223 | Religion | CA | $2,335,814Small | 50.63 |
| The Mission at Kern CountyEIN 95-1890705 | Human Services | CA | $4,091,592Mid-sized | 83.89 |
| The Mission ContinuesEIN 20-8742553 | Human Services | MO | $10,862,831Mid-sized | 100.00 |
| The Mockingbird SocietyEIN 91-2051340 | Human Services | WA | $2,216,828Small | 90.26 |
| The More ProjectEIN 20-3770594 | International | UT | $537,285Small | 60.15 |
| The Morgan Library & MuseumEIN 13-1624146 | Arts, Culture, Humanities | NY | $25,933,283Large | 87.87 |
| The Morton ArboretumEIN 36-1505770 | Environment | IL | $34,397,968Large | 91.76 |
| The Mother Divine ProgramEIN 95-2485909 | Religion | NY | $1,929,640Small | 79.87 |
| The MountEIN 04-2666846 | Arts, Culture, Humanities | MA | $2,021,432Small | 87.85 |
| The Mountain InstituteEIN 55-0541323 | Environment | DC | $2,301,129Small | 80.82 |
| The Mr. Holland's Opus FoundationEIN 95-4604927 | Education | CA | $1,895,014Small | 95.80 |
| The Multiple Myeloma Research FoundationEIN 06-1504413 | Health | CT | $30,536,598Large | 98.23 |
| The Municipal Art Society of New YorkEIN 13-5562288 | Community Development | NY | $4,121,783Mid-sized | 77.83 |
| The Museum of Chinese in AmericaEIN 11-2517055 | Arts, Culture, Humanities | NY | $3,141,818Small | 77.19 |
| The Museum of Contemporary Art, Los AngelesEIN 95-3433820 | Arts, Culture, Humanities | CA | $20,004,107Large | 88.87 |
| The Museum of Fine Arts, HoustonEIN 74-1109655 | Arts, Culture, Humanities | TX | $93,408,860Large | 88.15 |
| The Museum of Modern ArtEIN 13-1624100 | Arts, Culture, Humanities | NY | $252,692,693Large | 91.83 |
| The Museum of the African DiasporaEIN 94-3338239 | Arts, Culture, Humanities | CA | $2,592,132Small | 74.89 |
| The Mustard SeedEIN 64-0652510 | Human Services | MS | $1,279,530Small | 86.29 |
| The Myositis AssociationEIN 54-1660976 | Health | VA | $1,753,124Small | 97.05 |
| The NASCAR FoundationEIN 30-0337745 | Education | FL | $3,140,329Small | 84.21 |
| The Nation InstituteEIN 13-6216903 | Arts, Culture, Humanities | NY | $3,820,229Mid-sized | 89.39 |
| The National Academy Museum and School of Fine ArtsEIN 13-1628183 | Arts, Culture, Humanities | NY | $4,058,007Mid-sized | 80.38 |
| The National Center on Addiction and Substance AbuseEIN 52-1736502 | Health | NY | $10,701,678Mid-sized | 92.91 |
| The National Centre for Padre PioEIN 23-1897941 | Religion | PA | $1,210,838Small | 82.75 |
| The National Children's Cancer SocietyEIN 37-1227890 | International | MO | $12,829,470Mid-sized | 73.00 |
| The National Council for Science and the EnvironmentEIN 52-1700932 | Research and Public Policy | DC | $1,393,600Small | 59.46 |
| The National GEM ConsortiumEIN 31-0898802 | Education | VA | $3,179,013Small | 91.09 |