| Foundation for the Mid SouthEIN 72-1151070 | Community Development | MS | $2,079,629Small | 90.19 |
| Foundation for the National Institutes of HealthEIN 52-1986675 | Health | MD | $56,663,813Large | 96.20 |
| Foundation of Orthopedics and Complex Spine, Inc. (FOCOS)EIN 13-4047356 | Health | NY | $3,190,491Small | 81.64 |
| Foundation of Shalom ParkEIN 58-1477833 | Community Development | NC | $3,347,463Small | 79.77 |
| Foundation to Eradicate DuchenneEIN 71-0874241 | Health | VA | $926,691Small | 84.28 |
| Four Bands Community FundEIN 46-0456528 | Community Development | SD | $1,394,016Small | 88.22 |
| Four Corners MinistriesEIN 20-3589685 | Religion | AL | $684,010Small | 88.00 |
| Four Corners School of Outdoor EducationEIN 39-1509336 | Education | UT | $2,473,360Small | 91.67 |
| Four States Christian MissionsEIN 52-0704473 | Human Services | MD | $1,574,601Small | 82.11 |
| Fourth Street ClinicEIN 87-0569356 | Health | UT | $7,465,281Mid-sized | 93.71 |
| Fox Cities Performing Arts CenterEIN 39-1977839 | Arts, Culture, Humanities | WI | $7,485,449Mid-sized | 83.27 |
| Fox Valley Christian ActionEIN 36-2911588 | Human Services | IL | $1,446,069Small | 84.68 |
| FramelineEIN 94-2775772 | Arts, Culture, Humanities | CA | $1,992,256Small | 87.52 |
| Franciscan Foundation for the Holy LandEIN 33-0628775 | Religion | DC | $2,478,438Small | 96.28 |
| Franciscan OutreachEIN 36-2928835 | Human Services | IL | $2,970,873Small | 88.16 |
| Franklin and Eleanor Roosevelt InstituteEIN 23-7213592 | Arts, Culture, Humanities | NY | $6,807,755Mid-sized | 90.37 |
| Franklin News FoundationEIN 26-4066298 | Research and Public Policy | IL | $4,189,004Mid-sized | 66.66 |
| FRAXA Research FoundationEIN 04-3222167 | Health | MA | $1,497,101Small | 97.17 |
| Frederick Rescue MissionEIN 52-0813371 | Human Services | MD | $3,569,445Mid-sized | 91.61 |
| Fredericksburg Area Food BankEIN 54-1255013 | Human Services | VA | $9,390,605Mid-sized | 91.30 |
| Frederik Meijer Gardens & Sculpture FoundationEIN 38-3118579 | Environment | MI | $4,455,748Mid-sized | 91.46 |
| Frederik Meijer Gardens & Sculpture ParkEIN 38-2394044 | Environment | MI | $19,104,355Large | 90.50 |
| Free Arts NYCEIN 13-3958495 | Human Services | NY | $1,782,779Small | 74.91 |
| Free PressEIN 41-2106721 | Human and Civil Rights | MA | $3,278,337Small | 96.04 |
| Free Software FoundationEIN 04-2888848 | Human and Civil Rights | MA | $1,233,394Small | 96.66 |
| Free Speech TVEIN 51-0173482 | Arts, Culture, Humanities | CO | $3,482,605Small | 82.04 |
| Free Spirit MediaEIN 36-4456215 | Education | IL | $1,828,094Small | 92.74 |
| Free The KidsEIN 22-3741436 | Human Services | NC | $3,425,714Small | 94.74 |
| Free the SlavesEIN 56-2189635 | International | DC | $3,086,993Small | 82.07 |
| Free To Choose NetworkEIN 52-1455677 | Arts, Culture, Humanities | PA | $3,734,838Mid-sized | 88.55 |
| Free Wheelchair MissionEIN 31-1781635 | International | CA | $9,315,991Mid-sized | 87.18 |
| Freedom AllianceEIN 54-1411430 | Human and Civil Rights | VA | $6,409,316Mid-sized | 90.18 |
| Freedom FoundationEIN 94-3136961 | Research and Public Policy | WA | $4,123,043Mid-sized | 78.12 |
| Freedom from HungerEIN 95-1647835 | International | CA | $3,691,576Mid-sized | 82.21 |
| Freedom From Religion FoundationEIN 39-1302520 | Human and Civil Rights | WI | $4,478,081Mid-sized | 95.05 |
| Freedom in Christ MinistriesEIN 33-0361836 | Religion | TN | $1,510,904Small | 89.48 |
| Freedom InstituteEIN 13-2877912 | Health | NY | $4,742,217Mid-sized | 80.08 |
| Freedom School PartnersEIN 56-2169158 | Education | NC | $2,391,219Small | 83.16 |
| Freedom Service Dogs of AmericaEIN 84-1068936 | Animals | CO | $2,887,720Small | 93.15 |
| FreeStore FoodBankEIN 23-7122205 | Human Services | OH | $56,407,957Large | 92.73 |
| French Camp AcademyEIN 64-0321520 | Education | MS | $7,979,114Mid-sized | 90.67 |
| French Heritage SocietyEIN 13-3100091 | Arts, Culture, Humanities | NY | $1,971,733Small | 80.13 |
| French Institute Alliance FrançaiseEIN 13-1624099 | Arts, Culture, Humanities | NY | $12,169,973Mid-sized | 77.87 |
| French-American FoundationEIN 13-2847092 | International | NY | $1,277,280Small | 83.56 |
| Fresh Lifelines for YouthEIN 52-2234595 | Human Services | CA | $5,181,104Mid-sized | 90.90 |
| Fresh Start Women's FoundationEIN 86-0762610 | Human Services | AZ | $2,697,904Small | 86.41 |
| Fresh Youth InitiativesEIN 13-3723207 | Human Services | NY | $1,366,763Small | 99.02 |
| Fresno PhilharmonicEIN 94-1309738 | Arts, Culture, Humanities | CA | $1,553,890Small | 71.72 |
| Fresno Rescue MissionEIN 94-1279785 | Human Services | CA | $5,422,448Mid-sized | 78.52 |
| Friedreich's Ataxia Research AllianceEIN 52-2122720 | Health | PA | $6,811,814Mid-sized | 98.23 |
| Friendly HouseEIN 93-0524232 | Human Services | OR | $1,774,807Small | 81.80 |
| Friends for Animals of Metro DetroitEIN 38-3171570 | Animals | MI | $1,509,057Small | 91.42 |
| Friends for LifeEIN 26-0020294 | Animals | TX | $1,308,842Small | 90.85 |
| FRIENDS in Action InternationalEIN 77-0296087 | Religion | PA | $1,404,493Small | 64.78 |
| Friends of AcadiaEIN 01-0425071 | Environment | ME | $3,913,667Mid-sized | 93.37 |
| Friends of AnimalsEIN 13-6018549 | Animals | CT | $5,114,007Mid-sized | 90.62 |
| Friends of Cabrillo Marine AquariumEIN 33-0585381 | Animals | CA | $1,338,237Small | 88.88 |
| Friends of Cancer ResearchEIN 52-1983273 | Health | DC | $3,503,121Mid-sized | 77.93 |
| Friends of ChimboteEIN 45-0453441 | Human Services | ND | $1,572,177Small | 86.59 |
| Friends of Disabled Adults and ChildrenEIN 58-1709436 | Human Services | GA | $5,343,150Mid-sized | 93.04 |