| The Huntington Library, Art Collections, and Botanical GardensEIN 95-1644589 | Arts, Culture, Humanities | CA | $75,523,759Large | 92.00 |
| The Idea VillageEIN 45-0470675 | Community Development | LA | $2,405,571Small | 94.54 |
| The Immokalee FoundationEIN 65-0315664 | Education | FL | $3,144,627Small | 93.67 |
| The Independent InstituteEIN 94-3008370 | Research and Public Policy | CA | $3,196,579Small | 96.38 |
| The INNEIN 11-2676892 | Human Services | NY | $7,100,719Mid-sized | 90.56 |
| The Ireland Funds AmericaEIN 25-1306992 | International | MA | $33,128,738Large | 91.16 |
| The Irish Repertory TheatreEIN 13-3531713 | Arts, Culture, Humanities | NY | $4,241,257Mid-sized | 92.22 |
| The Jackson LaboratoryEIN 01-0211513 | Health | ME | $335,594,164Large | 95.21 |
| The Jed FoundationEIN 13-4131139 | Health | NY | $4,630,866Mid-sized | 95.33 |
| The Jewish Community Center of Greater ColumbusEIN 31-4379496 | Human Services | OH | $10,577,878Mid-sized | 92.50 |
| The Joffrey BalletEIN 36-4009741 | Arts, Culture, Humanities | IL | $19,599,699Large | 91.61 |
| The John F. Kennedy Center for the Performing ArtsEIN 53-0245017 | Arts, Culture, Humanities | DC | $227,384,468Large | 90.46 |
| The Julian CenterEIN 35-1346514 | Human Services | IN | $3,779,507Mid-sized | 91.57 |
| The Kalamazoo Civic TheatreEIN 38-1540000 | Arts, Culture, Humanities | MI | $2,612,218Small | 91.27 |
| The Kentucky United Methodist Homes for Children & YouthEIN 61-0458375 | Human Services | KY | $6,698,802Mid-sized | 90.80 |
| The Lamb CenterEIN 41-2222581 | Human Services | VA | $1,026,308Small | 92.44 |
| The Land InstituteEIN 48-0842156 | Research and Public Policy | KS | $3,570,717Mid-sized | 92.36 |
| The Library FoundationEIN 93-1190983 | Arts, Culture, Humanities | OR | $2,569,779Small | 95.77 |
| The Living DesertEIN 95-3385354 | Animals | CA | $12,284,906Mid-sized | 97.58 |
| The Lord's PlaceEIN 59-2240502 | Human Services | FL | $7,433,411Mid-sized | 95.60 |
| The Los Angeles ConservancyEIN 95-3273046 | Arts, Culture, Humanities | CA | $2,409,119Small | 91.19 |
| The Los Angeles PhilharmonicEIN 95-1696734 | Arts, Culture, Humanities | CA | $130,412,242Large | 93.73 |
| The Lustgarten Foundation for Pancreatic Cancer ResearchEIN 31-1611837 | Health | NY | $22,729,922Large | 100.00 |
| The Mailbox ClubEIN 23-7229445 | Religion | GA | $3,215,222Small | 93.91 |
| The Maine Children's Home for Little WanderersEIN 01-0267392 | Human Services | ME | $2,473,057Small | 92.02 |
| The Marfan FoundationEIN 52-1265361 | Health | NY | $4,465,668Mid-sized | 91.83 |
| The Marin Humane SocietyEIN 94-1156562 | Animals | CA | $8,260,861Mid-sized | 96.31 |
| The Marine Mammal CenterEIN 51-0144434 | Animals | CA | $10,612,857Mid-sized | 95.00 |
| The Mariners' MuseumEIN 54-0541801 | Arts, Culture, Humanities | VA | $10,573,622Mid-sized | 93.91 |
| The Maryland SPCAEIN 52-6001558 | Animals | MD | $6,592,967Mid-sized | 95.12 |
| The Midnight MissionEIN 95-1691293 | Human Services | CA | $9,508,855Mid-sized | 94.78 |
| The Mind TrustEIN 20-4560286 | Education | IN | $6,929,027Mid-sized | 92.22 |
| The Minneapolis FoundationEIN 41-6029402 | Community Development | MN | $70,849,060Large | 94.48 |
| The Minneapolis Institute of ArtsEIN 41-0693915 | Arts, Culture, Humanities | MN | $41,681,111Large | 92.05 |
| The Mint MuseumsEIN 56-0670666 | Arts, Culture, Humanities | NC | $10,388,083Mid-sized | 91.95 |
| The Mission ContinuesEIN 20-8742553 | Human Services | MO | $10,862,831Mid-sized | 100.00 |
| The Mockingbird SocietyEIN 91-2051340 | Human Services | WA | $2,216,828Small | 90.26 |
| The Morton ArboretumEIN 36-1505770 | Environment | IL | $34,397,968Large | 91.76 |
| The Mr. Holland's Opus FoundationEIN 95-4604927 | Education | CA | $1,895,014Small | 95.80 |
| The Multiple Myeloma Research FoundationEIN 06-1504413 | Health | CT | $30,536,598Large | 98.23 |
| The Museum of Modern ArtEIN 13-1624100 | Arts, Culture, Humanities | NY | $252,692,693Large | 91.83 |
| The Myositis AssociationEIN 54-1660976 | Health | VA | $1,753,124Small | 97.05 |
| The National Center on Addiction and Substance AbuseEIN 52-1736502 | Health | NY | $10,701,678Mid-sized | 92.91 |
| The National GEM ConsortiumEIN 31-0898802 | Education | VA | $3,179,013Small | 91.09 |
| The National Security ArchiveEIN 22-2127884 | International | DC | $2,850,713Small | 92.61 |
| The Naval Institute FoundationEIN 52-1814344 | Research and Public Policy | MD | $8,295,643Mid-sized | 95.11 |
| The NEA FoundationEIN 23-7035089 | Education | DC | $7,031,231Mid-sized | 94.37 |
| The New Children's MuseumEIN 95-3619583 | Arts, Culture, Humanities | CA | $4,690,365Mid-sized | 93.50 |
| The New PathEIN 31-1710997 | Human Services | OH | $2,547,017Small | 93.22 |
| The New World FoundationEIN 13-1919791 | Human and Civil Rights | NY | $18,406,528Large | 92.22 |
| The New York Botanical GardenEIN 13-1693134 | Environment | NY | $85,186,570Large | 90.56 |
| The New York Public LibraryEIN 13-1887440 | Arts, Culture, Humanities | NY | $341,319,058Large | 91.19 |
| The New-York Historical SocietyEIN 13-1624124 | Arts, Culture, Humanities | NY | $33,697,074Large | 92.75 |
| The Night MinistryEIN 36-3145764 | Human Services | IL | $6,860,954Mid-sized | 94.16 |
| The NOAH CenterEIN 91-1362069 | Animals | WA | $1,814,084Small | 90.00 |
| The Ocean FoundationEIN 71-0863908 | Environment | DC | $6,252,396Mid-sized | 93.79 |
| The Open Door ShelterEIN 22-2536909 | Human Services | CT | $3,396,115Small | 96.35 |
| The Oregon Community FoundationEIN 23-7315673 | Community Development | OR | $116,579,036Large | 96.40 |
| The Outreach Foundation EIN 58-1375506 | Religion | TN | $7,809,020Mid-sized | 93.06 |
| The Outreach ProgramEIN 20-0636360 | International | IA | $4,983,526Mid-sized | 90.28 |