| Thistle FarmsEIN 58-2050089 | Human Services | TN | $3,578,410Mid-sized | 88.43 |
| Thompson Island Outward Bound Education Center (TIOBEC)EIN 04-3027900 | Education | MA | $6,866,009Mid-sized | 90.06 |
| Thornwell Home for ChildrenEIN 57-0314418 | Human Services | SC | $9,386,658Mid-sized | 96.11 |
| Thousand CurrentsEIN 77-0071852 | International | CA | $4,669,023Mid-sized | 94.22 |
| Thrive NetworksEIN 33-0316095 | International | CA | $8,327,900Mid-sized | 84.76 |
| Time of Grace MinistryEIN 31-1739040 | Religion | WI | $3,888,300Mid-sized | 84.46 |
| Timmy Global HealthEIN 35-2012757 | International | IN | $4,235,537Mid-sized | 85.85 |
| Tisch MS Research Center of New YorkEIN 25-1922851 | Health | NY | $6,857,534Mid-sized | 86.98 |
| Toledo SymphonyEIN 34-4005365 | Arts, Culture, Humanities | OH | $6,534,395Mid-sized | 86.39 |
| Tomche Shabbos of Rockland CountyEIN 13-3694712 | Human Services | NY | $3,504,634Mid-sized | 66.01 |
| Tony La Russa's Animal Rescue FoundationEIN 68-0240341 | Animals | CA | $7,940,833Mid-sized | 100.00 |
| Topeka Rescue MissionEIN 48-0688068 | Human Services | KS | $4,817,236Mid-sized | 92.22 |
| TostanEIN 98-0118876 | International | DC | $6,631,431Mid-sized | 90.18 |
| Touch FoundationEIN 20-1469976 | International | NY | $4,365,452Mid-sized | 89.06 |
| Tourette Association of AmericaEIN 23-7191992 | Health | NY | $5,050,104Mid-sized | 84.85 |
| Town of Palm Beach United WayEIN 59-0637885 | Community Development | FL | $4,666,122Mid-sized | 97.83 |
| Tragedy Assistance Program for SurvivorsEIN 92-0152268 | Human Services | VA | $11,309,946Mid-sized | 95.02 |
| Transportation AlternativesEIN 51-0186015 | Environment | NY | $4,074,816Mid-sized | 83.96 |
| Travis Manion FoundationEIN 41-2237951 | Human Services | PA | $5,922,286Mid-sized | 94.56 |
| TreeHouse, MinnesotaEIN 36-3287099 | Human Services | MN | $4,442,991Mid-sized | 86.19 |
| Treehouse, WashingtonEIN 91-1425676 | Human Services | WA | $11,036,215Mid-sized | 92.05 |
| TreePeopleEIN 23-7314838 | Environment | CA | $5,561,824Mid-sized | 80.56 |
| Trees AtlantaEIN 58-1584758 | Environment | GA | $3,567,979Mid-sized | 99.30 |
| Tri-City Union Gospel MissionEIN 91-0840528 | Human Services | WA | $6,775,047Mid-sized | 97.17 |
| Tribeca Film InstituteEIN 80-0006057 | Arts, Culture, Humanities | NY | $4,432,179Mid-sized | 79.99 |
| Trickle UpEIN 06-1043042 | International | NY | $4,274,095Mid-sized | 91.84 |
| Trident United WayEIN 57-0314378 | Community Development | SC | $9,311,453Mid-sized | 89.08 |
| Trinity Broadcasting of New YorkEIN 14-1631995 | Religion | NY | $4,518,055Mid-sized | 66.12 |
| Trinity Broadcasting of TexasEIN 74-1945661 | Religion | TX | $4,212,032Mid-sized | 66.14 |
| Trinity Habitat for HumanityEIN 75-2239189 | Community Development | TX | $7,425,099Mid-sized | 95.23 |
| Trinity Repertory CompanyEIN 22-2547262 | Arts, Culture, Humanities | RI | $9,185,193Mid-sized | 90.82 |
| Troops DirectEIN 27-3046842 | Human Services | CA | $4,469,769Mid-sized | 84.28 |
| Truth For LifeEIN 34-1787585 | Religion | OH | $10,092,567Mid-sized | 97.04 |
| Tulsa BalletEIN 73-0667485 | Arts, Culture, Humanities | OK | $7,005,557Mid-sized | 92.14 |
| Tulsa Habitat for HumanityEIN 73-1325063 | Community Development | OK | $5,413,408Mid-sized | 91.68 |
| Tulsa Library TrustEIN 51-0165881 | Arts, Culture, Humanities | OK | $9,385,003Mid-sized | 84.34 |
| Turnstone Center for Disabled Children and AdultsEIN 35-0913541 | Human Services | IN | $6,027,867Mid-sized | 92.63 |
| Turtle Bay Exploration ParkEIN 68-0236299 | Arts, Culture, Humanities | CA | $5,807,778Mid-sized | 80.07 |
| Two River Theater CompanyEIN 52-1857757 | Arts, Culture, Humanities | NJ | $6,348,940Mid-sized | 90.94 |
| Two Ten Footwear FoundationEIN 22-2579809 | Human Services | MA | $5,594,243Mid-sized | 90.26 |
| U.S. Ski and Snowboard Team FoundationEIN 84-6030639 | Human Services | UT | $12,608,521Mid-sized | 84.76 |
| UCP Wheels for HumanityEIN 95-4581144 | International | CA | $6,086,262Mid-sized | 88.31 |
| Ukrainian Catholic Education FoundationEIN 36-4126296 | Religion | IL | $5,822,751Mid-sized | 91.78 |
| ULI FoundationEIN 23-7133957 | Community Development | DC | $6,498,365Mid-sized | 90.36 |
| Union Gospel Mission of Tarrant CountyEIN 75-6054677 | Human Services | TX | $7,236,943Mid-sized | 89.77 |
| Union Gospel Mission, SacramentoEIN 94-6103618 | Human Services | CA | $3,824,237Mid-sized | 81.57 |
| Union League Boys & Girls ClubsEIN 36-2167939 | Human Services | IL | $5,382,975Mid-sized | 94.07 |
| Union MissionEIN 55-6000896 | Human Services | WV | $5,449,476Mid-sized | 76.91 |
| Union Mission MinistriesEIN 54-0506427 | Human Services | VA | $7,945,549Mid-sized | 87.63 |
| Union Station Homeless ServicesEIN 95-3958741 | Human Services | CA | $9,281,855Mid-sized | 95.60 |
| Unitarian Universalist Service CommitteeEIN 04-6186012 | International | MA | $9,534,499Mid-sized | 96.26 |
| United AbilityEIN 63-0307960 | Health | AL | $11,695,930Mid-sized | 95.29 |
| United Arts of Central FloridaEIN 59-1166446 | Arts, Culture, Humanities | FL | $6,374,533Mid-sized | 87.36 |
| United Board for Christian Higher Education in AsiaEIN 13-5562367 | Religion | NY | $8,360,082Mid-sized | 84.42 |
| United Community Ministries (UCM of Alexandria)EIN 54-0850780 | Human Services | VA | $4,600,611Mid-sized | 83.84 |
| United Food Bank and Services of Plant CityEIN 59-3069728 | Human Services | FL | $3,768,609Mid-sized | 77.44 |
| United Friends of the ChildrenEIN 95-3665186 | Human Services | CA | $6,758,738Mid-sized | 91.79 |
| United Hospice of RocklandEIN 13-3425315 | Human Services | NY | $7,838,564Mid-sized | 87.25 |
| United Hospital FundEIN 13-1562656 | Research and Public Policy | NY | $11,358,050Mid-sized | 83.89 |
| United Methodist Children's HomeEIN 63-0302145 | Human Services | AL | $6,238,851Mid-sized | 89.59 |