| USO of IllinoisEIN 36-2349617 | Human Services | IL | $4,341,986Mid-sized | 95.71 |
| USO of Metropolitan New YorkEIN 13-2500122 | Human Services | NY | $12,528,590Mid-sized | 91.45 |
| USO of North CarolinaEIN 56-0532315 | Human Services | NC | $5,486,271Mid-sized | 90.32 |
| USTA FoundationEIN 13-3782331 | Human Services | NY | $4,393,091Mid-sized | 97.23 |
| Utah Festival Opera & Musical TheatreEIN 87-0498252 | Arts, Culture, Humanities | UT | $3,609,839Mid-sized | 85.77 |
| Vaad Harabbanim L'Inyanei TzedukaEIN 37-1456890 | Religion | NJ | $13,419,115Mid-sized | 60.04 |
| Venture Philanthropy PartnersEIN 31-1713618 | Education | DC | $6,182,794Mid-sized | 92.38 |
| Vermont PBSEIN 22-2990644 | Arts, Culture, Humanities | VT | $6,252,993Mid-sized | 84.38 |
| Vermont Public RadioEIN 03-0259051 | Arts, Culture, Humanities | VT | $10,455,459Mid-sized | 93.48 |
| Vero Beach Museum of ArtEIN 59-1867408 | Arts, Culture, Humanities | FL | $5,645,222Mid-sized | 78.39 |
| Veterans of Foreign Wars FoundationEIN 43-1758998 | Human Services | MO | $5,213,406Mid-sized | 96.38 |
| Veterans of Foreign Wars National Home for ChildrenEIN 38-1359597 | Human Services | MI | $5,064,859Mid-sized | 84.79 |
| Veterans Support FoundationEIN 13-3648561 | Human Services | MD | $4,546,213Mid-sized | 28.86 |
| VH1 Save The Music FoundationEIN 13-6089816 | Education | NY | $4,156,917Mid-sized | 77.90 |
| Victory Junction Gang Camp, Inc.EIN 56-2215292 | Health | NC | $5,925,573Mid-sized | 85.51 |
| Vietnam Veterans Memorial FundEIN 52-1149668 | Arts, Culture, Humanities | VA | $7,809,676Mid-sized | 87.20 |
| Village MissionsEIN 43-6043847 | Religion | OR | $6,234,120Mid-sized | 82.66 |
| VillageReachEIN 91-2083484 | International | WA | $10,203,423Mid-sized | 96.46 |
| Virgin Unite USAEIN 20-3963486 | International | NY | $4,301,437Mid-sized | 86.56 |
| Virginia Beach SPCAEIN 54-6061532 | Animals | VA | $4,485,642Mid-sized | 91.36 |
| Virginia Historical SocietyEIN 54-0419452 | Arts, Culture, Humanities | VA | $8,739,990Mid-sized | 89.76 |
| Virginia Living MuseumEIN 54-6055922 | Arts, Culture, Humanities | VA | $4,694,541Mid-sized | 91.94 |
| Virginia OperaEIN 54-0985006 | Arts, Culture, Humanities | VA | $5,542,726Mid-sized | 70.53 |
| Virginia Symphony OrchestraEIN 54-6000598 | Arts, Culture, Humanities | VA | $6,166,765Mid-sized | 74.59 |
| Visalia Rescue MissionEIN 94-2902666 | Human Services | CA | $7,934,260Mid-sized | 92.03 |
| Vision HouseEIN 91-1493474 | Human Services | WA | $3,764,200Mid-sized | 93.82 |
| VisionCorpsEIN 23-1352349 | Human Services | PA | $9,212,907Mid-sized | 93.49 |
| VisionSpringEIN 31-1811558 | International | NY | $3,511,730Mid-sized | 91.55 |
| VisionTrust InternationalEIN 84-1397081 | International | CO | $6,948,919Mid-sized | 87.16 |
| Vital Voices Global PartnershipEIN 52-2151557 | International | DC | $11,776,730Mid-sized | 93.88 |
| Vogel AlcoveEIN 75-2133827 | Human Services | TX | $5,168,292Mid-sized | 76.82 |
| Voices for Children, CAEIN 95-3786047 | Human Services | CA | $5,633,674Mid-sized | 85.99 |
| Volunteers Enlisted to Assist PeopleEIN 41-6175999 | Human Services | MN | $9,729,321Mid-sized | 86.74 |
| Volunteers in Medicine Hilton Head IslandEIN 57-0959206 | Health | SC | $3,881,951Mid-sized | 91.87 |
| Voto LatinoEIN 20-1350252 | Human and Civil Rights | DC | $4,117,249Mid-sized | 89.48 |
| Wadsworth AtheneumEIN 06-0653111 | Arts, Culture, Humanities | CT | $13,424,486Mid-sized | 92.19 |
| Walk Thru the BibleEIN 93-0669857 | Religion | GA | $3,715,197Mid-sized | 70.91 |
| WAMC/Northeast Public RadioEIN 22-2400593 | Arts, Culture, Humanities | NY | $6,962,673Mid-sized | 85.51 |
| Warren VillageEIN 84-0644270 | Community Development | CO | $4,887,533Mid-sized | 91.46 |
| Washington Performing Arts SocietyEIN 52-6062439 | Arts, Culture, Humanities | DC | $7,236,213Mid-sized | 81.71 |
| Washington Trails AssociationEIN 91-0900134 | Environment | WA | $4,256,309Mid-sized | 94.55 |
| Waste NotEIN 86-0650514 | Human Services | AZ | $6,247,728Mid-sized | 94.69 |
| Water Street MinistriesEIN 23-6004676 | Human Services | PA | $8,892,212Mid-sized | 87.22 |
| WaterAid AmericaEIN 30-0181674 | International | NY | $10,641,812Mid-sized | 87.71 |
| Watoto Child Care Ministry, Inc.EIN 59-3445250 | International | FL | $6,902,949Mid-sized | 86.49 |
| Wave HillEIN 13-6178903 | Environment | NY | $7,249,821Mid-sized | 87.08 |
| Wayside Christian MissionEIN 61-0667139 | Human Services | KY | $4,993,939Mid-sized | 84.83 |
| WBGOEIN 22-2137728 | Arts, Culture, Humanities | NJ | $5,107,014Mid-sized | 85.32 |
| WEAVEEIN 94-2493158 | Human Services | CA | $6,294,326Mid-sized | 88.29 |
| Wellfleet Harbor Actors TheaterEIN 04-3491049 | Arts, Culture, Humanities | MA | $5,347,405Mid-sized | 74.26 |
| Wesley Community CenterEIN 74-1132578 | Human Services | TX | $3,783,210Mid-sized | 95.80 |
| West Central InitiativeEIN 36-3453471 | Community Development | MN | $6,374,827Mid-sized | 89.90 |
| West Texas Food BankEIN 75-2057692 | Human Services | TX | $12,418,548Mid-sized | 87.75 |
| Western Center on Law & PovertyEIN 95-2897721 | Human and Civil Rights | CA | $4,003,531Mid-sized | 88.05 |
| Western Reserve Historical SocietyEIN 34-0714724 | Arts, Culture, Humanities | OH | $6,397,465Mid-sized | 94.12 |
| Western Resource AdvocatesEIN 84-1113831 | Environment | CO | $4,931,267Mid-sized | 94.54 |
| Western Tidewater Free ClinicEIN 26-3302837 | Health | VA | $10,958,717Mid-sized | 91.45 |
| Western Wall Heritage FoundationEIN 13-3468352 | Arts, Culture, Humanities | NY | $7,258,165Mid-sized | 66.05 |
| Westmoreland County Food BankEIN 25-1422682 | Human Services | PA | $11,874,832Mid-sized | 90.51 |
| Westport Country PlayhouseEIN 23-7357943 | Arts, Culture, Humanities | CT | $4,838,615Mid-sized | 88.74 |