| Center for Immigration StudiesEIN 52-1449368 | Research and Public Policy | DC | $2,816,435Small | 88.40 |
| Center for Individual RightsEIN 52-1600481 | Human and Civil Rights | DC | $1,689,279Small | 94.58 |
| Center for Inspired TeachingEIN 52-1944180 | Education | DC | $2,133,311Small | 90.58 |
| Center for International Environmental LawEIN 52-1633220 | Environment | DC | $2,606,242Small | 96.20 |
| Center for Justice and International LawEIN 52-1730890 | International | DC | $1,825,964Small | 79.33 |
| Center for Leadership DevelopmentEIN 35-1389882 | Education | IN | $2,164,081Small | 84.98 |
| Center for Media and DemocracyEIN 39-1777402 | Arts, Culture, Humanities | WI | $1,843,241Small | 82.77 |
| Center for Mind-Body MedicineEIN 52-1755744 | Health | DC | $2,257,174Small | 74.85 |
| Center for Planning ExcellenceEIN 20-3827040 | Community Development | LA | $1,719,044Small | 82.76 |
| Center for Public Interest ResearchEIN 04-2863170 | Research and Public Policy | MA | $3,214,538Small | 71.66 |
| Center for Resilient CitiesEIN 39-1854762 | Community Development | WI | $562,695Small | 78.95 |
| Center for Responsive PoliticsEIN 52-1275227 | Human and Civil Rights | DC | $2,117,097Small | 97.10 |
| Center for Teaching QualityEIN 04-3606319 | Education | NC | $2,140,229Small | 84.11 |
| Center for the HomelessEIN 35-1768544 | Human Services | IN | $3,240,450Small | 85.36 |
| Center for the New EconomyEIN 66-0566096 | Research and Public Policy | PR | $2,308,832Small | 87.15 |
| Center for Third World OrganizingEIN 52-1211059 | Human and Civil Rights | CA | $679,062Small | 59.78 |
| Center for Urban Renewal and EducationEIN 31-1467594 | Research and Public Policy | DC | $1,671,710Small | 78.59 |
| Center for Women & EnterpriseEIN 04-3256236 | Community Development | MA | $2,797,407Small | 84.58 |
| Center for Women in TransitionEIN 38-2181204 | Human Services | MI | $2,733,719Small | 90.72 |
| Center for Wooden BoatsEIN 91-1061721 | Education | WA | $1,600,728Small | 73.42 |
| Center of ConcernEIN 52-0941367 | Human and Civil Rights | DC | $931,090Small | 61.71 |
| Center of the American ExperimentEIN 36-3611426 | Research and Public Policy | MN | $2,247,617Small | 77.54 |
| Center on Policy InitiativesEIN 33-0824881 | Research and Public Policy | CA | $2,041,680Small | 91.84 |
| Centers for the Arts of Bonita SpringsEIN 65-0295085 | Arts, Culture, Humanities | FL | $2,634,919Small | 85.14 |
| Central American Medical OutreachEIN 34-1740695 | International | OH | $2,489,025Small | 86.05 |
| Central Coast Alliance United for A Sustainable EconomyEIN 77-0578864 | Human and Civil Rights | CA | $1,051,634Small | 88.85 |
| Central Iowa Shelter & ServicesEIN 42-1394212 | Human Services | IA | $2,529,003Small | 90.09 |
| Central Ohio Diabetes AssociationEIN 31-6054100 | Health | OH | $1,223,080Small | 73.68 |
| Central ScholarshipEIN 52-6012589 | Education | MD | $1,899,217Small | 96.74 |
| Centre County United WayEIN 25-1215290 | Community Development | PA | $1,792,114Small | 91.96 |
| CentroEIN 41-1290349 | Human Services | MN | $1,493,898Small | 90.38 |
| Centurion MinistriesEIN 22-2563979 | Human and Civil Rights | NJ | $1,587,880Small | 92.25 |
| Cerebral Palsy FoundationEIN 13-6093337 | Health | NY | $1,808,965Small | 82.51 |
| CERGE-EI FoundationEIN 25-1725738 | International | NJ | $3,260,105Small | 92.14 |
| Chabad's Children of ChernobylEIN 13-3722594 | International | NY | $172,434Small | 58.25 |
| Challenge AspenEIN 84-1315910 | Human Services | CO | $3,320,748Small | 100.00 |
| Challenged Child & FriendsEIN 58-1622732 | Education | GA | $2,311,777Small | 80.16 |
| Chamber Music AmericaEIN 13-2934575 | Arts, Culture, Humanities | NY | $2,826,648Small | 91.12 |
| Chamber Music NorthwestEIN 23-7355562 | Arts, Culture, Humanities | OR | $1,637,657Small | 95.38 |
| Champaign County Humane SocietyEIN 37-0714217 | Animals | IL | $1,058,761Small | 85.28 |
| Changed LivesEIN 62-6081698 | Religion | TN | $1,145,541Small | 94.37 |
| Channel 3 Kids CampEIN 06-0660003 | Education | CT | $2,401,293Small | 70.71 |
| Chapman School of SeamanshipEIN 59-1416396 | Education | FL | $1,966,950Small | 76.20 |
| Charcot-Marie-Tooth AssociationEIN 22-2480896 | Health | PA | $2,539,687Small | 87.39 |
| Charity NewsiesEIN 31-6401150 | Human Services | OH | $1,919,088Small | 94.28 |
| Charles River Watershed AssociationEIN 04-6136989 | Environment | MA | $1,159,643Small | 76.43 |
| Charleston Symphony OrchestraEIN 57-6000192 | Arts, Culture, Humanities | SC | $3,490,071Small | 89.02 |
| Charleston Wine + Food FestivalEIN 20-2671674 | Arts, Culture, Humanities | SC | $3,135,643Small | 85.49 |
| Charlotte Family HousingEIN 58-1599120 | Human Services | NC | $3,197,515Small | 93.41 |
| Chattahoochee RiverkeeperEIN 58-2095413 | Environment | GA | $2,483,987Small | 95.05 |
| Chattanooga Symphony & OperaEIN 62-6002098 | Arts, Culture, Humanities | TN | $2,521,056Small | 87.15 |
| Cheetah Conservation FundEIN 31-1726923 | Animals | VA | $2,458,012Small | 91.55 |
| Cherokee National Historical SocietyEIN 73-6103406 | Arts, Culture, Humanities | OK | $1,360,287Small | 58.58 |
| Cherry Creek Arts FestivalEIN 74-2546811 | Arts, Culture, Humanities | CO | $2,530,675Small | 84.55 |
| Chesapeake Climate Action NetworkEIN 11-3644283 | Environment | MD | $1,350,959Small | 91.29 |
| Chess in the SchoolsEIN 13-6119036 | Education | NY | $2,849,813Small | 84.95 |
| CHEST FoundationEIN 36-3286520 | Health | IL | $1,575,560Small | 89.58 |
| Chicago Arts Partnerships in EducationEIN 36-3969334 | Education | IL | $1,393,218Small | 81.00 |
| Chicago CaresEIN 36-3777709 | Community Development | IL | $3,287,575Small | 90.59 |
| Chicago Coalition for the HomelessEIN 36-3292607 | Human Services | IL | $2,898,914Small | 100.00 |