| Lifeword Media MinistriesEIN 71-0394665 | Religion | AR | $1,317,048Small | 74.57 |
| LIFTEIN 52-2168409 | Human Services | DC | $5,586,830Mid-sized | 79.56 |
| LiftFundEIN 74-2712770 | Community Development | TX | $16,726,193Large | 91.10 |
| Lifting GenerationsEIN 80-0001164 | International | UT | $1,750,813Small | 81.62 |
| Light Bearers MinistryEIN 91-1320416 | Religion | OR | $2,143,996Small | 78.76 |
| Light of Life Rescue MissionEIN 25-1056389 | Human Services | PA | $6,393,424Mid-sized | 90.12 |
| LightHawkEIN 84-0852104 | Environment | CO | $1,589,618Small | 85.34 |
| Lighthouse Children's HomeEIN 59-1725801 | Human Services | FL | $1,736,706Small | 72.86 |
| Lighthouse Family RetreatEIN 58-2509728 | Health | GA | $2,313,452Small | 83.31 |
| LightHouse for the Blind and Visually ImpairedEIN 94-1415317 | Human Services | CA | $12,324,154Mid-sized | 95.17 |
| Lighthouse Ministries, FloridaEIN 59-1722768 | Human Services | FL | $3,656,333Mid-sized | 85.85 |
| Lighthouse of Broward CountyEIN 59-1650909 | Human Services | FL | $1,874,571Small | 96.22 |
| Ligonier MinistriesEIN 25-1298611 | Religion | FL | $21,587,586Large | 89.44 |
| Lincoln Center for the Performing ArtsEIN 13-1847137 | Arts, Culture, Humanities | NY | $171,260,689Large | 90.26 |
| Lincoln Center TheaterEIN 13-3004747 | Arts, Culture, Humanities | NY | $44,380,044Large | 91.88 |
| Lincoln Children's MuseumEIN 47-0716636 | Arts, Culture, Humanities | NE | $1,529,973Small | 86.62 |
| Lincoln Park ZooEIN 36-2512404 | Animals | IL | $43,412,852Large | 85.43 |
| Lindsay Wildlife MuseumEIN 94-6104179 | Arts, Culture, Humanities | CA | $2,679,461Small | 87.12 |
| LINK Unlimited ScholarsEIN 23-7386928 | Education | IL | $2,710,923Small | 83.38 |
| Linn Benton Food ShareEIN 93-1099406 | Human Services | OR | $8,991,492Mid-sized | 93.49 |
| Lions Clubs International FoundationEIN 23-7030455 | Human Services | IL | $58,459,538Large | 90.69 |
| LISTEN Community ServicesEIN 23-7225952 | Human Services | NH | $2,434,586Small | 91.15 |
| Literacy ActionEIN 58-1053728 | Education | GA | $1,905,616Small | 90.52 |
| Literacy Assistance CenterEIN 13-3179618 | Education | NY | $1,917,881Small | 86.84 |
| Literacy Coalition of Palm Beach CountyEIN 65-0169781 | Education | FL | $4,764,772Mid-sized | 91.91 |
| Literacy PartnersEIN 51-0180665 | Education | NY | $2,411,788Small | 87.70 |
| Literacy, Inc.EIN 13-3911331 | Education | NY | $2,604,693Small | 89.64 |
| Literary ArtsEIN 93-0909494 | Education | OR | $2,167,145Small | 85.87 |
| Little Bit Therapeutic Riding Center EIN 91-1012131 | Health | WA | $2,283,394Small | 84.02 |
| Little Kids RockEIN 94-3396568 | Education | NJ | $5,555,404Mid-sized | 89.88 |
| Little League BaseballEIN 23-1688231 | Human Services | PA | $29,597,459Large | 86.96 |
| Little Light HouseEIN 73-0939422 | Education | OK | $2,305,990Small | 99.32 |
| Little Red Door Cancer AgencyEIN 35-0914096 | Health | IN | $1,916,196Small | 86.46 |
| Little Sisters of the Assumption Family Health ServiceEIN 13-2867881 | Human Services | NY | $4,959,509Mid-sized | 86.04 |
| Little Sisters of the Poor at St. Martin's BaltimoreEIN 52-0715244 | Human Services | MD | $7,179,367Mid-sized | 77.26 |
| Little Sisters of the Poor of IndianapolisEIN 35-1007734 | Human Services | IN | $6,639,356Mid-sized | 77.89 |
| Little Sisters of the Poor of PittsburghEIN 25-0974310 | Human Services | PA | $7,719,894Mid-sized | 85.58 |
| Little Sisters of the Poor of Washington, DCEIN 53-0227542 | Human Services | DC | $9,711,423Mid-sized | 81.54 |
| LitWorldEIN 13-4367685 | Education | NY | $1,372,881Small | 79.95 |
| Live ActionEIN 42-1764425 | Human and Civil Rights | VA | $3,359,488Small | 71.34 |
| Livermore Valley Performing Arts CenterEIN 68-0419182 | Arts, Culture, Humanities | CA | $3,917,776Mid-sized | 90.54 |
| Lives Under Construction Boys RanchEIN 46-0368556 | Human Services | MO | $1,358,480Small | 78.47 |
| Livestrong FoundationEIN 74-2806618 | Health | TX | $15,394,301Large | 83.66 |
| LiveWell ColoradoEIN 26-2464764 | Research and Public Policy | CO | $4,006,804Mid-sized | 86.84 |
| Living Arts & Science CenterEIN 61-0675663 | Arts, Culture, Humanities | KY | $883,955Small | 88.93 |
| Living Beyond Breast CancerEIN 23-2734689 | Health | PA | $4,561,647Mid-sized | 96.12 |
| Living Classrooms FoundationEIN 52-1369524 | Education | MD | $9,077,404Mid-sized | 90.20 |
| Living GoodsEIN 20-5010527 | International | CA | $9,618,119Mid-sized | 89.24 |
| Living Hope InternationalEIN 39-2000544 | Human Services | WI | $1,445,293Small | 84.44 |
| Living Lands and WatersEIN 36-4244353 | Environment | IL | $2,001,281Small | 92.43 |
| Living on the EdgeEIN 46-0484695 | Religion | GA | $5,163,751Mid-sized | 83.59 |
| Living Water InternationalEIN 76-0324875 | International | TX | $24,044,401Large | 83.01 |
| Living WatersEIN 27-0094016 | Religion | CA | $3,413,862Small | 65.71 |
| Livingston County United WayEIN 38-2174453 | Community Development | MI | $1,582,147Small | 89.39 |
| Lloyd Center for the EnvironmentEIN 04-3066693 | Environment | MA | $761,737Small | 87.94 |
| Loaves & Fishes Community ServicesEIN 36-3786777 | Human Services | IL | $12,840,978Mid-sized | 93.61 |
| Loaves & Fishes, CharlotteEIN 56-1398498 | Human Services | NC | $3,158,747Small | 90.60 |
| Loaves and FishesEIN 41-1421522 | Human Services | MN | $3,338,845Small | 85.79 |
| Loaves and Fishes for St. LouisEIN 43-1251264 | Human Services | MO | $1,905,288Small | 86.60 |
| Lobero Theatre FoundationEIN 95-1831068 | Arts, Culture, Humanities | CA | $2,980,948Small | 83.58 |