| D-Rev Design for the Other Ninety PercentEIN 26-0642778 | Health | CA | $1,828,897Small | 88.06 |
| D. James Kennedy MinistriesEIN 65-0496702 | Religion | FL | $4,790,042Mid-sized | 85.12 |
| D.A.R.E. AmericaEIN 95-4242541 | Health | CA | $12,067,579Mid-sized | 70.66 |
| D.C. Bar Pro Bono CenterEIN 52-1574217 | Human and Civil Rights | DC | $2,824,873Small | 93.74 |
| D.C. Central KitchenEIN 52-1584936 | Human Services | DC | $16,677,394Large | 92.92 |
| Dakin Humane SocietyEIN 20-5318898 | Animals | MA | $3,483,198Small | 87.67 |
| Dakota Indian FoundationEIN 23-7112391 | Human Services | SD | $591,852Small | 27.44 |
| Dalit Freedom NetworkEIN 41-2075995 | International | VA | $2,220,867Small | 80.83 |
| Dallas Area Habitat for HumanityEIN 75-2097161 | Community Development | TX | $20,413,100Large | 91.70 |
| Dallas ContemporaryEIN 75-1575687 | Arts, Culture, Humanities | TX | $1,826,588Small | 87.23 |
| Dallas Holocaust MuseumEIN 75-2113723 | Arts, Culture, Humanities | TX | $3,316,399Small | 84.85 |
| Dallas Life FoundationEIN 75-2336522 | Human Services | TX | $4,054,566Mid-sized | 94.85 |
| Dallas Museum of ArtEIN 75-0808774 | Arts, Culture, Humanities | TX | $28,537,301Large | 81.64 |
| Dallas Theater CenterEIN 75-0959992 | Arts, Culture, Humanities | TX | $10,134,614Mid-sized | 81.30 |
| Dallas Zoological SocietyEIN 75-0964982 | Animals | TX | $12,677,533Mid-sized | 88.08 |
| Damon Runyon Cancer Research FoundationEIN 13-1933825 | Health | NY | $19,596,662Large | 94.78 |
| Dan Marino FoundationEIN 65-0320556 | Health | FL | $3,486,858Small | 93.39 |
| Dana-Farber Cancer InstituteEIN 04-2263040 | Health | MA | $1,528,239,259Large | 92.74 |
| Dance ExchangeEIN 52-1076232 | Arts, Culture, Humanities | MD | $447,360Small | 79.19 |
| Dance Theatre of HarlemEIN 13-2642091 | Arts, Culture, Humanities | NY | $5,536,736Mid-sized | 83.11 |
| Dance/USAEIN 52-1253457 | Arts, Culture, Humanities | DC | $2,307,036Small | 87.61 |
| Dane County Humane SocietyEIN 39-0806335 | Animals | WI | $3,719,068Mid-sized | 87.15 |
| Danforth ArtEIN 04-2526917 | Arts, Culture, Humanities | MA | $1,216,820Small | 75.73 |
| Daniel Murphy Scholarship FundEIN 36-3675466 | Education | IL | $3,844,516Mid-sized | 90.96 |
| Daniel Pitino ShelterEIN 61-1245271 | Human Services | KY | $1,558,230Small | 74.44 |
| Danita's ChildrenEIN 59-3735653 | International | TN | $2,153,385Small | 90.35 |
| DAPCEPEIN 38-2451827 | Education | MI | $2,229,825Small | 83.85 |
| Dare 2 Share MinistriesEIN 84-0504202 | Religion | CO | $3,524,068Mid-sized | 85.23 |
| Dare to Care Food BankEIN 23-7345952 | Human Services | KY | $43,226,997Large | 97.26 |
| Daughters of Charity Services of San AntonioEIN 74-6106876 | Human Services | TX | $6,688,924Mid-sized | 89.78 |
| Daughters of the American RevolutionEIN 53-0205923 | Arts, Culture, Humanities | DC | $16,267,791Large | 75.61 |
| DAV (Disabled American Veterans) Charitable Service TrustEIN 52-1521276 | Human Services | KY | $7,103,580Mid-sized | 92.01 |
| Dave Thomas Foundation for AdoptionEIN 31-1356151 | Human Services | OH | $24,102,108Large | 96.29 |
| David Lynch Foundation for Consciousness-Based EducationEIN 83-0436453 | Education | NY | $12,365,779Mid-sized | 92.14 |
| David's HouseEIN 22-2593431 | Health | NH | $935,493Small | 77.06 |
| Davis Phinney FoundationEIN 20-0813566 | Health | CO | $1,889,395Small | 89.37 |
| Days End Farm Horse RescueEIN 52-1759077 | Animals | MD | $1,570,461Small | 90.22 |
| Dayspring InternationalEIN 51-0237239 | Religion | VA | $7,364,681Mid-sized | 72.03 |
| DaySpring VillaEIN 73-1474319 | Human Services | OK | $1,234,000Small | 84.00 |
| DaystarEIN 62-1244203 | Human Services | TN | $2,070,139Small | 85.73 |
| Daystar Life CenterEIN 65-0523539 | Human Services | FL | $1,115,568Small | 91.36 |
| Dayton Art InstituteEIN 31-0537480 | Arts, Culture, Humanities | OH | $5,217,588Mid-sized | 84.58 |
| Dayton Contemporary Dance CompanyEIN 23-7220259 | Arts, Culture, Humanities | OH | $1,339,004Small | 72.01 |
| Dayton HistoryEIN 31-6037490 | Arts, Culture, Humanities | OH | $5,703,691Mid-sized | 92.22 |
| Dayton Masonic FoundationEIN 31-1385609 | Arts, Culture, Humanities | OH | $780,648Small | 80.86 |
| Dayton Performing Arts AllianceEIN 31-6000101 | Arts, Culture, Humanities | OH | $8,167,915Mid-sized | 83.97 |
| Dayton Society of Natural HistoryEIN 31-0585917 | Arts, Culture, Humanities | OH | $5,296,073Mid-sized | 79.89 |
| DEA Educational FoundationEIN 52-1922097 | Health | DC | $1,197,681Small | 81.54 |
| Deborah Hospital FoundationEIN 22-2049500 | Health | NJ | $11,597,550Mid-sized | 93.83 |
| Deborah's PlaceEIN 36-3382973 | Human Services | IL | $3,473,862Small | 94.48 |
| DeCordova Sculpture Park and MuseumEIN 04-2067315 | Arts, Culture, Humanities | MA | $4,862,222Mid-sized | 79.43 |
| Defenders of Animal RightsEIN 52-1061126 | Animals | MD | $1,124,255Small | 83.40 |
| Delancey Street FoundationEIN 23-7102690 | Human Services | CA | $102,283,206Large | 91.45 |
| Delaware Art MuseumEIN 51-0065746 | Arts, Culture, Humanities | DE | $5,189,312Mid-sized | 87.68 |
| Delaware Humane AssociationEIN 51-0082499 | Animals | DE | $1,765,553Small | 88.10 |
| Delaware Museum of Natural HistoryEIN 51-0083535 | Arts, Culture, Humanities | DE | $2,423,622Small | 89.09 |
| Delaware Nature SocietyEIN 51-6018321 | Environment | DE | $4,326,285Mid-sized | 91.54 |
| Delaware Riverkeeper NetworkEIN 74-3255972 | Environment | PA | $2,931,825Small | 88.44 |
| Delaware Valley Golden Retriever RescueEIN 23-2775413 | Animals | PA | $1,370,710Small | 85.34 |
| Delivering GoodEIN 13-3300271 | Human Services | NY | $217,120,707Large | 94.69 |