| Ronald McDonald House Charities of DenverEIN 84-0728926 | Health | CO | $3,629,604Mid-sized | 96.53 |
| Ronald McDonald House Charities of Eastern Iowa and Western IllinoisEIN 42-1189783 | Health | IA | $1,707,135Small | 92.16 |
| Ronald McDonald House Charities of Eastern WisconsinEIN 39-1433107 | Health | WI | $2,818,682Small | 97.05 |
| Ronald McDonald House Charities of Greater ChattanoogaEIN 62-1327855 | Health | TN | $2,009,604Small | 90.34 |
| Ronald McDonald House Charities of Greater CincinnatiEIN 31-0965333 | Health | OH | $4,698,361Mid-sized | 92.80 |
| Ronald McDonald House Charities of Greater Washington, DCEIN 52-1132262 | Health | DC | $3,306,024Small | 92.68 |
| Ronald McDonald House Charities of JacksonvilleEIN 59-2625008 | Health | FL | $3,069,398Small | 90.58 |
| Ronald McDonald House Charities of Kansas CityEIN 43-1190760 | Health | MO | $4,464,880Mid-sized | 94.66 |
| Ronald McDonald House Charities of Oklahoma CityEIN 73-1103242 | Health | OK | $1,421,972Small | 91.88 |
| Ronald McDonald House Charities of RochesterEIN 16-1271311 | Health | NY | $2,519,326Small | 92.23 |
| Ronald McDonald House Charities of Southeastern MichiganEIN 38-2182406 | Health | MI | $2,024,980Small | 92.46 |
| Ronald McDonald House Charities of St. LouisEIN 43-1160478 | Health | MO | $4,156,934Mid-sized | 90.61 |
| Ronald McDonald House Charities of Tampa BayEIN 59-1835985 | Health | FL | $3,252,462Small | 93.36 |
| Ronald McDonald House Charities of the Intermountain AreaEIN 74-2386043 | Health | UT | $3,478,094Small | 94.68 |
| Ronald McDonald House Charities of the Upper MidwestEIN 41-1313107 | Health | MN | $5,009,431Mid-sized | 91.52 |
| Ronald McDonald House Charities of Western Washington & AlaskaEIN 91-1061043 | Health | WA | $4,295,376Mid-sized | 92.56 |
| Ronald McDonald House of Chapel HillEIN 56-1413188 | Health | NC | $1,989,118Small | 91.44 |
| Ronald McDonald House of DallasEIN 75-1609401 | Health | TX | $2,128,984Small | 90.07 |
| Ronald McDonald House of Fort WorthEIN 75-1754490 | Health | TX | $2,435,858Small | 90.42 |
| Ronald McDonald House of Southern New JerseyEIN 22-2430393 | Health | NJ | $1,761,528Small | 93.86 |
| Room to GrowEIN 13-4012096 | Human Services | NY | $3,445,554Small | 91.27 |
| Room to ReadEIN 91-2003533 | International | CA | $53,102,212Large | 92.92 |
| Root CapitalEIN 04-3478123 | International | MA | $29,771,735Large | 92.38 |
| Rose Brooks CenterEIN 51-0231573 | Human Services | MO | $6,361,265Mid-sized | 90.48 |
| Rose Foundation for Communities and the EnvironmentEIN 94-3179772 | Environment | CA | $7,448,602Mid-sized | 100.00 |
| Rosenberg Fund for ChildrenEIN 04-3095890 | Education | MA | $701,693Small | 91.81 |
| Rosie's PlaceEIN 04-2582187 | Human Services | MA | $10,156,194Mid-sized | 91.81 |
| Roswell Park Alliance FoundationEIN 16-1391608 | Health | NY | $20,082,219Large | 95.63 |
| Rotaplast InternationalEIN 94-3247677 | International | CA | $1,532,916Small | 94.56 |
| Roundabout Theatre CompanyEIN 13-6192346 | Arts, Culture, Humanities | NY | $68,732,912Large | 96.18 |
| Row New YorkEIN 11-3632924 | Human Services | NY | $2,536,743Small | 90.40 |
| Royal Family Kids EIN 33-0380021 | Human Services | CA | $1,810,547Small | 94.32 |
| Ruffed Grouse SocietyEIN 54-0846925 | Animals | PA | $5,496,791Mid-sized | 97.23 |
| Rural Advancement Foundation International-USAEIN 56-1704863 | Environment | NC | $2,116,129Small | 100.00 |
| Ruth & Norman Rales Jewish Family ServiceEIN 65-1115689 | Human Services | FL | $11,478,842Mid-sized | 95.05 |
| Ryan HouseEIN 20-1852393 | Health | AZ | $2,506,047Small | 90.29 |
| Saban Community ClinicEIN 95-2539105 | Health | CA | $22,618,402Large | 93.91 |
| Sacramento Loaves & FishesEIN 68-0189897 | Human Services | CA | $6,533,895Mid-sized | 96.86 |
| Sacramento ZooEIN 94-2861667 | Animals | CA | $7,227,802Mid-sized | 91.17 |
| Sacred Heart Community ServiceEIN 23-7179787 | Human Services | CA | $22,848,309Large | 93.77 |
| Safe & SoundEIN 94-2455072 | Human Services | CA | $5,939,180Mid-sized | 94.17 |
| Safe ConnectionsEIN 43-1077667 | Human Services | MO | $2,357,049Small | 90.14 |
| Safe Haven Family ShelterEIN 62-1807653 | Human Services | TN | $2,082,147Small | 94.94 |
| Safe Water NetworkEIN 51-0570455 | International | NY | $4,401,103Mid-sized | 93.60 |
| SAFEchildEIN 56-1817816 | Human Services | NC | $1,394,963Small | 92.22 |
| SafeHaven of Tarrant CountyEIN 75-1670281 | Human Services | TX | $7,907,012Mid-sized | 92.70 |
| SAFEHOMEEIN 48-0917798 | Human Services | KS | $3,636,486Mid-sized | 96.19 |
| SafeHouse CenterEIN 38-2121751 | Human Services | MI | $2,244,935Small | 93.08 |
| SAG-AFTRA FoundationEIN 95-3967876 | Arts, Culture, Humanities | CA | $7,330,396Mid-sized | 91.90 |
| Saint Louis Zoo AssociationEIN 43-1727309 | Animals | MO | $16,950,536Large | 91.13 |
| Salina Rescue MissionEIN 48-0944358 | Human Services | KS | $1,309,100Small | 93.77 |
| Salk Institute for Biological StudiesEIN 95-2160097 | Health | CA | $119,364,264Large | 91.35 |
| Salvadoran American Humanitarian FoundationEIN 59-2339140 | International | FL | $25,123,269Large | 94.69 |
| Samaritan HouseEIN 23-7416272 | Human Services | CA | $10,205,305Mid-sized | 94.93 |
| Samaritan InnsEIN 52-1474935 | Human Services | DC | $3,384,447Small | 97.66 |
| Samaritan Ministry of Greater WashingtonEIN 52-1434143 | Human Services | DC | $1,171,383Small | 92.80 |
| Samaritan's FeetEIN 14-1880905 | International | NC | $7,532,515Mid-sized | 92.38 |
| Samaritan's PurseEIN 58-1437002 | International | NC | $595,259,892Large | 95.85 |
| San Angelo Area FoundationEIN 73-1634145 | Community Development | TX | $9,025,193Mid-sized | 91.42 |
| San Antonio Food BankEIN 74-2122979 | Human Services | TX | $129,142,157Large | 95.96 |