| ReadworksEIN 13-3593812 | Education | NY | $2,188,245Small | 93.91 |
| REAL School GardensEIN 20-5946552 | Education | DC | $2,996,732Small | 92.14 |
| Reason FoundationEIN 95-3298239 | Research and Public Policy | CA | $12,379,098Mid-sized | 94.64 |
| Reasons to BelieveEIN 33-0168048 | Religion | CA | $4,804,284Mid-sized | 90.16 |
| Rebuilding TogetherEIN 52-1585880 | Community Development | DC | $12,052,499Mid-sized | 91.81 |
| Rebuilding Together HoustonEIN 76-0027902 | Community Development | TX | $3,435,119Small | 90.91 |
| Rebuilding Together PeninsulaEIN 94-3106209 | Community Development | CA | $2,140,867Small | 93.77 |
| Rebuilding Together Silicon ValleyEIN 77-0289381 | Community Development | CA | $1,758,363Small | 96.66 |
| Red Hook InitiativeEIN 20-3904662 | Human Services | NY | $3,007,954Small | 90.14 |
| Red Mountain Theatre CompanyEIN 58-1994417 | Arts, Culture, Humanities | AL | $3,275,879Small | 90.58 |
| REDFEIN 54-2132153 | Human Services | CA | $13,282,944Mid-sized | 95.33 |
| RedRoverEIN 68-0124097 | Animals | CA | $2,614,195Small | 96.95 |
| Regional Food Bank of OklahomaEIN 73-1100380 | Human Services | OK | $84,517,598Large | 92.65 |
| Regional Parks FoundationEIN 23-7011877 | Environment | CA | $1,649,524Small | 90.50 |
| Reid Park Zoological SocietyEIN 94-2379052 | Animals | AZ | $4,017,037Mid-sized | 91.16 |
| Relief Nursery, Inc.EIN 93-0784800 | Human Services | OR | $3,472,400Small | 92.18 |
| Religious Community ServicesEIN 59-1309186 | Human Services | FL | $9,886,130Mid-sized | 91.45 |
| Reporters Committee for Freedom of the PressEIN 52-0972043 | Human and Civil Rights | DC | $1,982,840Small | 91.90 |
| Rescue Mission of El PasoEIN 74-6062443 | Human Services | TX | $1,764,164Small | 90.12 |
| Rescue Mission of Middle GeorgiaEIN 58-6011446 | Human Services | GA | $2,723,506Small | 96.07 |
| Rescue Mission of RoanokeEIN 54-0573900 | Human Services | VA | $4,755,474Mid-sized | 90.54 |
| Rescue Mission of TrentonEIN 21-0656182 | Human Services | NJ | $5,128,473Mid-sized | 90.92 |
| Resource and Crisis Center of Galveston CountyEIN 76-0121011 | Human Services | TX | $2,645,730Small | 91.88 |
| Resource Center EIN 75-1892059 | Health | TX | $7,437,379Mid-sized | 95.63 |
| Resource CentralEIN 84-0808982 | Environment | CO | $2,340,605Small | 92.51 |
| Resourcing Christian Education InternationalEIN 57-1154204 | Religion | IL | $6,823,625Mid-sized | 93.91 |
| reStartEIN 43-1349378 | Human Services | MO | $6,716,944Mid-sized | 90.58 |
| Restavek FreedomEIN 20-8334578 | International | OH | $2,310,841Small | 100.00 |
| Restless Legs Syndrome FoundationEIN 56-1784846 | Health | TX | $907,448Small | 91.16 |
| Restoration MinistriesEIN 36-3552070 | Human Services | IL | $2,526,753Small | 92.27 |
| Restore Hope MinistriesEIN 73-1037026 | Human Services | OK | $1,208,768Small | 91.55 |
| RESULTS Educational FundEIN 95-3747267 | Research and Public Policy | DC | $12,042,341Mid-sized | 92.82 |
| Retina Foundation of the SouthwestEIN 51-0151514 | Health | TX | $3,799,510Mid-sized | 92.62 |
| Rheumatology Research FoundationEIN 58-1654301 | Health | GA | $14,033,568Large | 92.22 |
| Richmond Ballet, The State Ballet of VirginiaEIN 54-6049848 | Arts, Culture, Humanities | VA | $7,064,503Mid-sized | 90.94 |
| Richmond SPCAEIN 54-0506328 | Animals | VA | $6,971,781Mid-sized | 91.87 |
| RIOULT Dance NYEIN 13-3700857 | Arts, Culture, Humanities | NY | $1,163,311Small | 92.68 |
| Rise Against HungerEIN 16-1541024 | International | NC | $49,757,061Large | 91.16 |
| Rising Tide CapitalEIN 11-3720098 | Human Services | NJ | $4,068,979Mid-sized | 95.65 |
| Rising Treetops at OakhurstEIN 13-5674230 | Health | NY | $2,351,959Small | 95.00 |
| River Bend FoodbankEIN 36-3147342 | Human Services | IA | $25,107,770Large | 98.23 |
| Riveredge Nature CenterEIN 39-6108549 | Environment | WI | $1,881,013Small | 91.18 |
| Riverfront RecaptureEIN 06-1045653 | Environment | CT | $3,088,203Small | 92.56 |
| RiverkeeperEIN 13-3204621 | Environment | NY | $4,274,476Mid-sized | 93.25 |
| Robert Toigo FoundationEIN 13-3565420 | Education | CA | $3,531,060Mid-sized | 94.48 |
| Robin Hood FoundationEIN 13-3441066 | Community Development | NY | $209,989,218Large | 94.26 |
| RocaEIN 22-3223641 | Human Services | MA | $11,234,089Mid-sized | 94.28 |
| Rockford Rescue MissionEIN 36-6132381 | Human Services | IL | $5,700,304Mid-sized | 90.10 |
| Rocking the BoatEIN 13-4177814 | Education | NY | $2,444,745Small | 90.42 |
| Rocky Mountain ConservancyEIN 84-0472090 | Environment | CO | $3,017,070Small | 96.63 |
| Rocky Mountain InstituteEIN 74-2244146 | Environment | CO | $33,402,821Large | 94.57 |
| Rodeheaver Boys RanchEIN 59-0830750 | Human Services | FL | $1,967,247Small | 94.56 |
| Roger Baldwin Foundation of ACLUEIN 36-2682569 | Human and Civil Rights | IL | $4,101,273Mid-sized | 92.22 |
| Ronald McDonald House CharitiesEIN 36-2934689 | Health | IL | $39,981,206Large | 92.82 |
| Ronald McDonald House Charities Bay AreaEIN 94-2538615 | Health | CA | $5,897,955Mid-sized | 90.60 |
| Ronald McDonald House Charities New York Tri-State AreaEIN 22-3188156 | Health | NJ | $2,499,626Small | 92.48 |
| Ronald McDonald House Charities of AugustaEIN 58-1509465 | Health | GA | $825,577Small | 91.93 |
| Ronald McDonald House Charities of Central and Northern ArizonaEIN 86-0483792 | Health | AZ | $2,976,662Small | 91.71 |
| Ronald McDonald House Charities of Central FloridaEIN 59-3211250 | Health | FL | $3,418,782Small | 91.33 |
| Ronald McDonald House Charities of CharlestonEIN 57-0724845 | Health | SC | $1,595,982Small | 91.89 |