| Boch CenterEIN 51-0197209 | Arts, Culture, Humanities | MA | $33,264,866Large | 91.98 |
| Books For AfricaEIN 41-1627391 | International | MN | $36,258,346Large | 100.00 |
| Boston BalletEIN 04-2312734 | Arts, Culture, Humanities | MA | $34,959,006Large | 86.74 |
| Boston Symphony OrchestraEIN 04-2103550 | Arts, Culture, Humanities | MA | $103,630,393Large | 84.74 |
| Boy Scouts of America National CouncilEIN 22-1576300 | Human Services | TX | $307,700,980Large | 88.14 |
| Boy Scouts of America Sam Houston Area CouncilEIN 76-0239833 | Human Services | TX | $13,580,295Large | 93.80 |
| Boy Scouts of America, Circle Ten CouncilEIN 75-0800615 | Human Services | TX | $16,741,048Large | 84.04 |
| Boy Scouts of America, Greater St. Louis Area CouncilEIN 43-0652676 | Human Services | MO | $14,161,285Large | 86.08 |
| Boys & Girls Clubs of AmericaEIN 13-5562976 | Human Services | GA | $174,331,184Large | 94.59 |
| Boys & Girls Clubs of BostonEIN 04-2103922 | Human Services | MA | $25,460,406Large | 95.03 |
| Boys & Girls Clubs of DelawareEIN 51-0068712 | Human Services | DE | $20,344,868Large | 89.77 |
| Boys & Girls Clubs of Greater MilwaukeeEIN 39-0806292 | Human Services | WI | $27,951,203Large | 94.26 |
| Boys & Girls Clubs of King CountyEIN 91-0532600 | Human Services | WA | $19,415,461Large | 96.37 |
| Boys & Girls Clubs of Metro AtlantaEIN 58-0566123 | Human Services | GA | $23,066,288Large | 96.21 |
| Boys & Girls Clubs of Metro DenverEIN 84-0510404 | Human Services | CO | $16,174,525Large | 87.02 |
| Boys & Girls Clubs of San FranciscoEIN 94-1156608 | Human Services | CA | $22,351,367Large | 95.73 |
| Boys Hope Girls Hope, Affiliates EIN 43-1209928 | Human Services | MO | $13,904,136Large | 84.80 |
| Boys TownEIN 47-0376606 | Human Services | NE | $325,615,341Large | 90.45 |
| Braille Institute of AmericaEIN 95-1641426 | Human Services | CA | $23,465,454Large | 87.11 |
| Brain & Behavior Research FoundationEIN 31-1020010 | Health | NY | $17,729,428Large | 90.71 |
| Breast Cancer Research FoundationEIN 13-3727250 | Health | NY | $76,886,163Large | 90.48 |
| Brennan Center for Justice at NYU School of LawEIN 13-3839293 | Human and Civil Rights | NY | $17,732,433Large | 91.92 |
| BrightFocus FoundationEIN 23-7337229 | Health | MD | $35,815,491Large | 82.58 |
| Broadway Cares/Equity Fights AIDSEIN 13-3458820 | Health | NY | $22,604,203Large | 81.84 |
| Brooklyn Academy of MusicEIN 11-2201344 | Arts, Culture, Humanities | NY | $51,562,831Large | 85.15 |
| Brooklyn Botanic GardenEIN 11-2417338 | Environment | NY | $22,441,961Large | 93.86 |
| Brooklyn MuseumEIN 11-1672743 | Arts, Culture, Humanities | NY | $43,855,989Large | 87.89 |
| Brother's Brother FoundationEIN 34-6562544 | International | PA | $119,695,345Large | 92.92 |
| BUILD (Businesses United in Investing, Lending & Development)EIN 94-3386695 | Education | CA | $13,514,301Large | 82.94 |
| buildOnEIN 22-3128648 | International | CT | $15,454,830Large | 93.73 |
| Cal Farley'sEIN 75-0808768 | Human Services | TX | $48,884,362Large | 84.04 |
| Cal Ripken, Sr. FoundationEIN 52-2310500 | Human Services | MD | $21,777,183Large | 90.45 |
| California Academy of SciencesEIN 94-1156258 | Arts, Culture, Humanities | CA | $87,733,463Large | 82.64 |
| California Charter Schools AssociationEIN 51-0465703 | Education | CA | $24,280,771Large | 88.22 |
| California Community FoundationEIN 95-3510055 | Community Development | CA | $189,261,881Large | 91.24 |
| California Emergency FoodlinkEIN 68-0275330 | Human Services | CA | $41,035,733Large | 94.03 |
| California Science Center FoundationEIN 95-2210527 | Arts, Culture, Humanities | CA | $25,189,988Large | 83.85 |
| Cambridge in AmericaEIN 52-6071299 | Education | NY | $86,183,618Large | 92.02 |
| Camillus HouseEIN 65-0032862 | Human Services | FL | $20,897,021Large | 90.92 |
| Campaign for Tobacco-Free KidsEIN 52-1969967 | Health | DC | $31,138,832Large | 95.05 |
| Cancer Research InstituteEIN 13-1837442 | Health | NY | $24,672,872Large | 92.18 |
| Canine Companions for IndependenceEIN 94-2494324 | Animals | CA | $26,185,688Large | 88.43 |
| Capital Area Food BankEIN 52-1167581 | Human Services | DC | $70,273,007Large | 90.15 |
| CAREEIN 13-1685039 | International | GA | $581,648,006Large | 87.02 |
| Care and Share Food Bank for Southern ColoradoEIN 84-0731930 | Human Services | CO | $44,807,576Large | 94.28 |
| Caring Voice CoalitionEIN 26-0058446 | Health | VA | $87,769,321Large | 89.20 |
| Carnegie Endowment for International PeaceEIN 13-0552040 | International | DC | $36,544,639Large | 86.94 |
| Carnegie Institution for ScienceEIN 53-0196523 | Research and Public Policy | DC | $100,297,805Large | 87.74 |
| Carnegie Museums of PittsburghEIN 25-0965280 | Arts, Culture, Humanities | PA | $60,885,821Large | 86.59 |
| Catholic Charities Archdiocese of New OrleansEIN 72-0408911 | Human Services | LA | $25,374,533Large | 87.30 |
| Catholic Charities CYO, Archdiocese of San FranciscoEIN 94-1498472 | Community Development | CA | $39,675,865Large | 91.21 |
| Catholic Charities Diocese of ClevelandEIN 34-1318541 | Human Services | OH | $94,796,377Large | 86.67 |
| Catholic Charities Diocese of St. PetersburgEIN 59-0875805 | Human Services | FL | $14,146,994Large | 90.63 |
| Catholic Charities Fort WorthEIN 75-0808769 | Human Services | TX | $36,791,584Large | 97.23 |
| Catholic Charities of BaltimoreEIN 52-0591538 | Human Services | MD | $110,847,148Large | 87.17 |
| Catholic Charities of BuffaloEIN 16-0743251 | Human Services | NY | $34,668,837Large | 91.01 |
| Catholic Charities of Los AngelesEIN 95-1690973 | Human Services | CA | $38,301,614Large | 96.16 |
| Catholic Charities of Northeast KansasEIN 48-1181305 | Human Services | KS | $25,350,672Large | 91.16 |
| Catholic Charities of Santa Clara CountyEIN 94-2762269 | Human Services | CA | $35,534,021Large | 87.91 |
| Catholic Charities of SpokaneEIN 91-0569880 | Human Services | WA | $16,225,818Large | 90.52 |