| Alliance of Resident Theatres/New YorkEIN 13-2768583 | Arts, Culture, Humanities | NY | $4,115,637Mid-sized | 91.58 |
| Alliance to Protect Nantucket SoundEIN 10-0008105 | Community Development | MA | $1,784,176Small | 69.69 |
| Alliance to Save EnergyEIN 52-1082991 | Environment | DC | $4,083,682Mid-sized | 70.28 |
| Allied Arts FoundationEIN 73-0804291 | Arts, Culture, Humanities | OK | $3,520,807Mid-sized | 84.42 |
| Almost Heaven Habitat for HumanityEIN 55-0685778 | Community Development | WV | $605,064Small | 69.37 |
| Aloha Council Boy Scouts of AmericaEIN 99-0073482 | Human Services | HI | $2,937,975Small | 86.01 |
| Aloha United WayEIN 99-0073494 | Community Development | HI | $13,846,084Large | 88.25 |
| Alpha House of TampaEIN 59-2655523 | Human Services | FL | $1,442,566Small | 89.72 |
| Alpha USAEIN 13-3962840 | Religion | IL | $8,024,235Mid-sized | 77.72 |
| Alpha-1 FoundationEIN 65-0585415 | Health | FL | $9,757,837Mid-sized | 97.13 |
| ALS Association Minnesota/North Dakota/South Dakota ChapterEIN 41-1756085 | Health | MN | $3,987,728Mid-sized | 88.65 |
| ALS Therapy Development InstituteEIN 04-3462719 | Health | MA | $12,533,202Mid-sized | 91.93 |
| AlternativesEIN 36-2720602 | Human Services | IL | $3,464,767Small | 83.96 |
| Alternatives in ActionEIN 94-3210413 | Education | CA | $4,028,999Mid-sized | 87.25 |
| Alternatives Incorporated of Madison CountyEIN 31-0986769 | Human Services | IN | $1,386,664Small | 86.35 |
| Alternatives Pregnancy CenterEIN 74-2218129 | Health | CO | $1,505,461Small | 85.35 |
| Alumni Association of Kansas State UniversityEIN 48-0495058 | Education | KS | $4,225,425Mid-sized | 83.30 |
| Alvin Ailey Dance FoundationEIN 13-2584273 | Arts, Culture, Humanities | NY | $40,518,013Large | 89.43 |
| Alzheimer's AssociationEIN 13-3039601 | Health | IL | $359,577,467Large | 88.70 |
| Alzheimer's Disease Association of Kern County Inc.EIN 77-0017561 | Human Services | CA | $899,578Small | 84.25 |
| Alzheimer's Family CenterEIN 95-3463975 | Human Services | CA | $4,400,117Mid-sized | 93.36 |
| Alzheimer's Foundation of AmericaEIN 91-1792864 | Health | NY | $6,562,695Mid-sized | 95.73 |
| Alzheimer's Research & Prevention FoundationEIN 86-0735832 | Health | AZ | $633,055Small | 80.50 |
| Alzheimer's Services of the East BayEIN 94-3081330 | Health | CA | $2,423,878Small | 74.44 |
| AmaraEIN 91-0577487 | Human Services | WA | $3,424,856Small | 92.08 |
| Amarillo Children's HomeEIN 75-0800666 | Human Services | TX | $2,746,191Small | 77.61 |
| Amazement SquareEIN 54-1713204 | Arts, Culture, Humanities | VA | $1,533,961Small | 88.61 |
| Amazima MinistriesEIN 61-1555718 | International | TN | $2,726,430Small | 96.92 |
| Amazing DiscoveriesEIN 20-4268927 | Religion | WA | $2,074,318Small | 78.78 |
| Amazing PlaceEIN 76-0604478 | Human Services | TX | $2,525,731Small | 81.13 |
| Amazon Conservation AssociationEIN 52-2211305 | Environment | DC | $5,038,940Mid-sized | 93.33 |
| Amazon Conservation TeamEIN 54-1915987 | Environment | VA | $6,486,299Mid-sized | 99.06 |
| Amazon WatchEIN 95-4604782 | Environment | CA | $1,686,512Small | 82.49 |
| Ambassadors for Christ International Ltd.EIN 58-2655669 | Religion | GA | $2,009,280Small | 82.04 |
| America's Car MuseumEIN 91-1867848 | Arts, Culture, Humanities | WA | $4,221,742Mid-sized | 84.28 |
| America's Family CoachesEIN 42-1430081 | Religion | IA | $809,159Small | 70.34 |
| America's KeswickEIN 21-0715335 | Religion | NJ | $4,262,848Mid-sized | 87.62 |
| America's Packard MuseumEIN 31-1340842 | Arts, Culture, Humanities | OH | $358,766Small | 72.36 |
| America's Promise AllianceEIN 54-1848713 | Human Services | DC | $11,854,378Mid-sized | 84.10 |
| America's Second Harvest of the Big BendEIN 59-2610345 | Human Services | FL | $12,057,541Mid-sized | 89.98 |
| America-Israel Cultural FoundationEIN 13-1664048 | Arts, Culture, Humanities | NY | $2,866,285Small | 86.34 |
| America-Israel Friendship LeagueEIN 23-7252135 | International | NY | $1,311,570Small | 82.23 |
| American Academy in BerlinEIN 52-1726273 | International | NY | $6,566,241Mid-sized | 84.15 |
| American Academy in RomeEIN 13-1623881 | International | NY | $12,511,030Mid-sized | 85.62 |
| American Academy of Arts and SciencesEIN 04-2103651 | Research and Public Policy | MA | $11,527,301Mid-sized | 91.00 |
| American Academy of Family Physicians FoundationEIN 44-6013671 | Health | KS | $4,372,723Mid-sized | 80.40 |
| American Alpine ClubEIN 13-1611981 | Environment | CO | $3,471,529Small | 73.05 |
| American Anti-Vivisection SocietyEIN 23-0341990 | Animals | PA | $2,044,004Small | 87.61 |
| American Architectural FoundationEIN 52-0847434 | Community Development | DC | $2,788,730Small | 78.80 |
| American Associates, Ben-Gurion University of the NegevEIN 23-7270753 | Education | NY | $47,792,268Large | 95.94 |
| American Association for the Advancement of ScienceEIN 53-0196568 | Research and Public Policy | DC | $107,624,973Large | 87.49 |
| American Association of Kidney PatientsEIN 11-2306416 | Health | FL | $1,102,458Small | 85.46 |
| American Association of People with DisabilitiesEIN 52-1930174 | Human and Civil Rights | DC | $1,360,471Small | 81.67 |
| American Autoimmune Related Diseases AssociationEIN 38-3027574 | Health | MI | $945,382Small | 98.45 |
| American Ballet TheatreEIN 13-1882106 | Arts, Culture, Humanities | NY | $45,050,346Large | 87.98 |
| American Bar Association Fund for Justice and EducationEIN 36-6110299 | Human and Civil Rights | IL | $74,100,402Large | 82.08 |
| American Battlefield TrustEIN 54-1426643 | Arts, Culture, Humanities | DC | $17,884,556Large | 96.94 |
| American Bird ConservancyEIN 52-1501259 | Animals | VA | $12,830,927Mid-sized | 91.41 |
| American Brain FoundationEIN 41-1717098 | Health | MN | $2,754,433Small | 77.61 |
| American Brain Tumor AssociationEIN 23-7286648 | Health | IL | $5,638,221Mid-sized | 89.86 |