| CHUMEIN 41-1227969 | Human Services | MN | $2,486,042Small | 90.23 |
| Church Health EIN 58-1716113 | Health | TN | $20,797,265Large | 94.58 |
| Church Hill Activities and TutoringEIN 20-0220263 | Education | VA | $2,156,767Small | 94.70 |
| Church World ServiceEIN 13-4080201 | International | IN | $65,527,734Large | 83.94 |
| Churches of Christ Disaster Relief EffortEIN 62-1560072 | Human Services | TN | $7,348,103Mid-sized | 85.15 |
| CIA Officers Memorial FoundationEIN 52-2360463 | Human Services | VA | $1,536,236Small | 99.25 |
| Cibolo Nature Center & FarmEIN 74-2564700 | Environment | TX | $3,672,517Mid-sized | 85.33 |
| Cincinnati Art MuseumEIN 31-0536653 | Arts, Culture, Humanities | OH | $14,729,738Large | 94.04 |
| Cincinnati BalletEIN 31-6050354 | Arts, Culture, Humanities | OH | $9,444,521Mid-sized | 87.20 |
| Cincinnati Nature CenterEIN 31-6057978 | Environment | OH | $4,653,544Mid-sized | 77.13 |
| Cincinnati OperaEIN 31-0549044 | Arts, Culture, Humanities | OH | $7,768,378Mid-sized | 90.18 |
| Cincinnati Parks FoundationEIN 31-1429016 | Environment | OH | $1,059,563Small | 89.02 |
| Cincinnati Public RadioEIN 31-1410636 | Arts, Culture, Humanities | OH | $5,945,935Mid-sized | 86.02 |
| Cincinnati Symphony OrchestraEIN 31-0537080 | Arts, Culture, Humanities | OH | $31,381,796Large | 91.96 |
| Cincinnati WorksEIN 31-1656186 | Human Services | OH | $3,222,679Small | 90.28 |
| Cincinnati Zoo & Botanical GardenEIN 31-0537171 | Animals | OH | $43,193,066Large | 90.73 |
| CinequestEIN 77-0250734 | Arts, Culture, Humanities | CA | $1,297,850Small | 88.19 |
| Circle Health ServicesEIN 23-7078501 | Health | OH | $5,547,953Mid-sized | 88.77 |
| Circle Of ConcernEIN 23-7085010 | Human Services | MO | $2,170,713Small | 86.52 |
| CIS Development FoundationEIN 22-3304404 | International | NJ | $41,239,855Large | 83.73 |
| CitiHope Relief & DevelopmentEIN 13-2907656 | International | NY | $148,169,686Large | 95.05 |
| Citizen SchoolsEIN 04-3259160 | Education | MA | $20,565,491Large | 85.00 |
| Citizens Against Government WasteEIN 52-1363952 | Human and Civil Rights | DC | $3,768,713Mid-sized | 83.69 |
| Citizens Commission on Human RightsEIN 68-0005541 | Human and Civil Rights | CA | $3,592,409Mid-sized | 80.30 |
| Citizens Committee for New York CityEIN 51-0171818 | Community Development | NY | $2,613,376Small | 93.18 |
| Citizens for Animal ProtectionEIN 23-7296260 | Animals | TX | $3,498,478Small | 90.68 |
| Citizens for Global Solutions Education FundEIN 52-6081813 | International | DC | $168,324Small | 72.93 |
| Citizens for Responsibility and Ethics in WashingtonEIN 03-0445391 | Human and Civil Rights | DC | $1,995,677Small | 81.04 |
| Citizens United for Research in EpilepsyEIN 36-4253176 | Health | IL | $6,070,422Mid-sized | 96.46 |
| Citizens United FoundationEIN 54-1626748 | Human and Civil Rights | DC | $3,554,360Mid-sized | 56.74 |
| Citizens' Committee for Children of New YorkEIN 13-5618593 | Human Services | NY | $2,913,471Small | 88.26 |
| Citrus Center Boys & Girls ClubEIN 59-0776417 | Human Services | FL | $1,022,421Small | 73.61 |
| City AcademyEIN 31-1619379 | Education | MO | $3,936,148Mid-sized | 86.36 |
| City HarvestEIN 13-3170676 | Human Services | NY | $123,039,582Large | 87.08 |
| City ImpactEIN 47-0800906 | Religion | NE | $1,076,962Small | 75.66 |
| City MissionEIN 25-1051749 | Human Services | PA | $6,720,515Mid-sized | 82.31 |
| City Mission of SchenectadyEIN 14-1403652 | Human Services | NY | $5,157,949Mid-sized | 99.34 |
| City of RefugeEIN 58-2194642 | Human Services | GA | $8,064,665Mid-sized | 86.10 |
| City Parks FoundationEIN 13-3561657 | Environment | NY | $20,273,100Large | 94.26 |
| City Rescue MissionEIN 59-1009115 | Human Services | FL | $5,461,593Mid-sized | 79.84 |
| City Rescue Mission of LansingEIN 38-1626400 | Human Services | MI | $3,402,158Small | 91.71 |
| City Rescue Mission of SaginawEIN 38-1368362 | Human Services | MI | $5,610,309Mid-sized | 94.69 |
| City Rescue Mission, Oklahoma CityEIN 73-0713883 | Human Services | OK | $6,209,143Mid-sized | 89.00 |
| City TheatreEIN 25-1554580 | Arts, Culture, Humanities | PA | $3,008,701Small | 86.90 |
| City Union Mission, Inc.EIN 44-6005481 | Human Services | MO | $14,140,675Large | 95.87 |
| City YearEIN 22-2882549 | Human Services | MA | $148,415,766Large | 92.67 |
| Citymeals-on-WheelsEIN 13-3634381 | Human Services | NY | $20,441,242Large | 90.36 |
| CitySquareEIN 75-2332948 | Human Services | TX | $20,653,887Large | 92.74 |
| CityteamEIN 94-1501265 | Human Services | CA | $26,665,848Large | 87.76 |
| Civic FederationEIN 36-2170124 | Research and Public Policy | IL | $1,724,422Small | 76.05 |
| Civic Garden Center of Greater CincinnatiEIN 31-0559893 | Environment | OH | $779,757Small | 79.83 |
| Clara White MissionEIN 59-6002104 | Human Services | FL | $2,278,850Small | 86.84 |
| Clare Boothe Luce Policy InstituteEIN 54-1672138 | Human and Civil Rights | VA | $1,351,379Small | 94.63 |
| Clarion ProjectEIN 20-5845679 | Research and Public Policy | DC | $2,549,070Small | 63.65 |
| Claris HealthEIN 95-4806856 | Health | CA | $1,155,601Small | 85.87 |
| Clark County Food BankEIN 91-1307564 | Human Services | WA | $11,160,692Mid-sized | 99.08 |
| Clarke Schools for Hearing and SpeechEIN 04-2104008 | Education | MA | $11,678,628Mid-sized | 82.72 |
| CLASPEIN 23-7000150 | Research and Public Policy | DC | $6,942,104Mid-sized | 95.42 |
| Classic Wines AuctionEIN 20-1260228 | Human Services | OR | $3,217,257Small | 82.82 |
| Classroom CentralEIN 03-0455618 | Education | NC | $5,729,370Mid-sized | 94.74 |