| Colorado Springs Fine Arts CenterEIN 84-0406947 | Arts, Culture, Humanities | CO | $6,797,225Mid-sized | 90.71 |
| Colorado Springs Philharmonic OrchestraEIN 74-3091110 | Arts, Culture, Humanities | CO | $3,917,452Mid-sized | 85.50 |
| Colorado SymphonyEIN 84-0511458 | Arts, Culture, Humanities | CO | $13,000,490Mid-sized | 82.60 |
| Colorado UpLiftEIN 84-0889330 | Education | CO | $5,716,706Mid-sized | 87.29 |
| Colorectal Cancer AllianceEIN 86-0947831 | Health | DC | $6,452,188Mid-sized | 90.18 |
| Columbia Lighthouse for the BlindEIN 53-0196609 | Human Services | DC | $6,245,235Mid-sized | 76.66 |
| Columbia Museum of ArtEIN 57-6007869 | Arts, Culture, Humanities | SC | $4,269,010Mid-sized | 78.98 |
| Columbia/Barnard HillelEIN 23-7077182 | Religion | NY | $2,790,514Small | 75.51 |
| Columbus Citizens FoundationEIN 13-6118967 | Education | NY | $4,362,512Mid-sized | 85.20 |
| Columbus HumaneEIN 31-4379492 | Animals | OH | $2,907,190Small | 87.61 |
| Columbus Museum of ArtEIN 31-4379447 | Arts, Culture, Humanities | OH | $13,970,682Large | 91.73 |
| Columbus Symphony OrchestraEIN 31-6402408 | Arts, Culture, Humanities | OH | $8,505,883Mid-sized | 86.14 |
| Columbus Zoo and AquariumEIN 31-4390844 | Animals | OH | $71,124,051Large | 92.24 |
| Combined Jewish PhilanthropiesEIN 04-2103559 | Community Development | MA | $166,682,869Large | 94.56 |
| Comfort Zone CampEIN 54-1916517 | Health | VA | $2,096,801Small | 74.85 |
| Comic Relief Inc.EIN 01-0885377 | Human Services | NY | $91,909,090Large | 89.02 |
| Coming CleanEIN 04-3429794 | Environment | VT | $984,122Small | 82.69 |
| Coming Home Network InternationalEIN 34-1732696 | Religion | OH | $1,542,591Small | 66.54 |
| CommentaryEIN 13-3610041 | Arts, Culture, Humanities | NY | $3,059,126Small | 90.59 |
| Commission To Every NationEIN 74-2730294 | Religion | TX | $17,045,573Large | 96.46 |
| Committee For A Constructive TomorrowEIN 52-1462893 | Environment | DC | $1,754,758Small | 70.10 |
| Committee for Accuracy in Middle East Reporting in AmericaEIN 52-1332702 | International | MA | $4,796,135Mid-sized | 93.69 |
| Committee on Temporary ShelterEIN 03-0285606 | Human Services | VT | $3,566,411Mid-sized | 88.33 |
| Committee to Protect JournalistsEIN 13-3081500 | Human and Civil Rights | NY | $7,345,573Mid-sized | 92.83 |
| Common Cause Education FundEIN 31-1705370 | Human and Civil Rights | DC | $7,223,861Mid-sized | 93.96 |
| Common Counsel FoundationEIN 94-3214166 | Community Development | CA | $3,914,023Mid-sized | 85.93 |
| Common HopeEIN 41-1560297 | International | MN | $4,867,551Mid-sized | 94.76 |
| Common Sense MediaEIN 41-2024986 | Arts, Culture, Humanities | CA | $22,906,362Large | 93.91 |
| Common ThreadsEIN 20-0106847 | Human Services | TX | $3,810,395Mid-sized | 91.24 |
| CommonBond CommunitiesEIN 41-1260469 | Community Development | MN | $13,518,416Large | 92.27 |
| CommonwealEIN 94-2366094 | Health | CA | $4,034,106Mid-sized | 93.02 |
| CommonwealthEIN 04-3540147 | Community Development | MA | $1,993,340Small | 91.42 |
| Commonwealth Foundation EIN 23-2473845 | Research and Public Policy | PA | $2,993,022Small | 88.36 |
| Communications Consortium Media CenterEIN 52-1524972 | Research and Public Policy | DC | $927,021Small | 79.49 |
| Communities for a Better EnvironmentEIN 94-2998086 | Environment | CA | $2,066,472Small | 83.88 |
| Communities Foundation of TexasEIN 75-0964565 | Community Development | TX | $129,532,950Large | 91.42 |
| Communities In Schools National OfficeEIN 58-1289174 | Education | VA | $20,927,294Large | 90.78 |
| Communities in Schools of Charlotte Mecklenburg, Inc.EIN 58-1661795 | Education | NC | $6,728,143Mid-sized | 92.07 |
| Communities in Schools of ChicagoEIN 36-3591326 | Education | IL | $2,653,240Small | 91.75 |
| Communities In Schools of GeorgiaEIN 58-1912923 | Education | GA | $2,649,158Small | 85.85 |
| Communities In Schools of HoustonEIN 76-0031827 | Education | TX | $12,788,149Mid-sized | 91.61 |
| Communities In Schools of JacksonvilleEIN 59-3027895 | Education | FL | $7,374,320Mid-sized | 82.87 |
| Communities In Schools of NevadaEIN 88-0292094 | Education | NV | $6,748,695Mid-sized | 91.30 |
| Communities In Schools of Pittsburgh-Allegheny CountyEIN 25-1728521 | Education | PA | $749,377Small | 82.02 |
| Communities in Schools of RichmondEIN 54-1799922 | Education | VA | $3,212,373Small | 87.37 |
| Communities in Schools of the Charleston AreaEIN 57-0915384 | Education | SC | $1,667,084Small | 85.38 |
| Communities In Schools of the Dallas RegionEIN 75-2044117 | Education | TX | $4,919,164Mid-sized | 84.87 |
| Community Action HouseEIN 23-7120670 | Human Services | MI | $2,417,828Small | 87.96 |
| Community Action Services and Food BankEIN 87-0491952 | Community Development | UT | $8,607,245Mid-sized | 86.84 |
| Community Action Stops AbuseEIN 59-2114359 | Human Services | FL | $4,663,766Mid-sized | 92.75 |
| Community Arts Music AssociationEIN 95-1816010 | Arts, Culture, Humanities | CA | $2,083,604Small | 88.35 |
| Community Assistance CenterEIN 58-1825565 | Human Services | GA | $2,666,088Small | 78.13 |
| Community Catalyst EIN 04-3355127 | Human and Civil Rights | MA | $12,149,963Mid-sized | 91.21 |
| Community Center for the ArtsEIN 83-0314362 | Arts, Culture, Humanities | WY | $2,916,695Small | 77.70 |
| Community CoalitionEIN 95-4298811 | Community Development | CA | $5,163,415Mid-sized | 91.86 |
| Community CooperativeEIN 59-2602772 | Human Services | FL | $3,203,307Small | 90.68 |
| Community Crusade for ChildrenEIN 06-1445929 | Education | CT | $2,472,428Small | 66.33 |
| Community Enrichment CenterEIN 75-2231694 | Human Services | TX | $3,585,846Mid-sized | 93.47 |
| Community Environmental CouncilEIN 94-1728064 | Environment | CA | $1,225,334Small | 87.24 |
| Community Family Life ServicesEIN 52-0910609 | Human Services | DC | $2,180,158Small | 88.28 |