| Texas Heart InstituteEIN 74-6053200 | Health | TX | $35,589,463Large | 77.25 |
| Texas Lions CampEIN 74-1189679 | Health | TX | $3,117,425Small | 86.98 |
| Texas Parks and Wildlife FoundationEIN 74-2602504 | Environment | TX | $6,241,257Mid-sized | 95.05 |
| Texas Public Policy FoundationEIN 74-2524057 | Research and Public Policy | TX | $8,681,038Mid-sized | 91.89 |
| Texas Public RadioEIN 74-2559514 | Arts, Culture, Humanities | TX | $4,888,453Mid-sized | 95.17 |
| Texas State AquariumEIN 23-7044950 | Animals | TX | $14,727,252Large | 92.93 |
| Texas State Historical AssociationEIN 74-6025220 | Arts, Culture, Humanities | TX | $2,690,694Small | 79.26 |
| Texas Tech Alumni AssociationEIN 75-6036607 | Education | TX | $3,700,697Mid-sized | 68.72 |
| TGR Foundation, A Tiger Woods CharityEIN 20-0677815 | Human Services | CA | $11,035,526Mid-sized | 93.03 |
| Thanks USAEIN 20-3973151 | Education | VA | $1,837,305Small | 94.64 |
| The 52nd Street ProjectEIN 13-3467948 | Human Services | NY | $2,060,817Small | 91.70 |
| The 92nd Street YEIN 13-1624229 | Human Services | NY | $69,602,246Large | 88.59 |
| The Ability ExperienceEIN 58-1588777 | Human Services | NC | $2,450,975Small | 86.99 |
| The Abraham Fund InitiativesEIN 13-3556715 | International | NY | $1,446,990Small | 81.05 |
| The Abraham Lincoln FoundationEIN 23-2822856 | Arts, Culture, Humanities | PA | $1,233,060Small | 77.53 |
| The Academy of Natural Sciences of Drexel UniversityEIN 23-1352000 | Arts, Culture, Humanities | PA | $20,069,886Large | 88.54 |
| The Acting CompanyEIN 13-2759292 | Arts, Culture, Humanities | NY | $2,167,703Small | 76.11 |
| The Action CenterEIN 23-7019679 | Human Services | CO | $13,852,593Large | 86.81 |
| The Actors FundEIN 13-1635251 | Arts, Culture, Humanities | NY | $34,504,429Large | 92.52 |
| The Adirondack CouncilEIN 14-1594386 | Environment | NY | $1,901,232Small | 97.45 |
| The Admiral Nimitz FoundationEIN 74-1492692 | Arts, Culture, Humanities | TX | $6,005,614Mid-sized | 96.37 |
| The Adoption ExchangeEIN 84-0793576 | Human Services | CO | $3,915,626Mid-sized | 82.34 |
| The Advocates for Human RightsEIN 36-3292374 | International | MN | $1,654,192Small | 90.07 |
| The African American Museum in PhiladelphiaEIN 23-1941617 | Arts, Culture, Humanities | PA | $2,632,733Small | 86.69 |
| The AIMS ProjectEIN 94-3231546 | International | CA | $323,087Small | 82.91 |
| The Albert Baker FundEIN 94-1613751 | Education | CA | $2,483,523Small | 76.38 |
| The Albert Schweitzer FellowshipEIN 13-1982786 | International | MA | $1,268,770Small | 82.77 |
| The Albertsons Companies FoundationEIN 91-2144510 | Community Development | CA | $46,816,024Large | 81.61 |
| The Aleph InstituteEIN 59-2291627 | Human Services | FL | $3,717,868Mid-sized | 80.10 |
| The Alliance CenterEIN 42-1622670 | Environment | CO | $1,402,869Small | 81.84 |
| The ALS Association Connecticut ChapterEIN 04-3417472 | Health | CT | $901,701Small | 88.66 |
| The ALS Association Georgia ChapterEIN 58-1943490 | Health | GA | $1,380,734Small | 96.04 |
| The ALS Association Golden West ChapterEIN 95-4163338 | Health | CA | $4,752,423Mid-sized | 92.85 |
| The ALS Association Greater New York ChapterEIN 13-3616680 | Health | NY | $5,132,118Mid-sized | 97.66 |
| The ALS Association Western Pennsylvania ChapterEIN 23-7123851 | Health | PA | $1,217,079Small | 96.66 |
| The ALS Association, Greater Philadelphia ChapterEIN 23-2387205 | Health | PA | $5,699,754Mid-sized | 87.34 |
| The ALS Association, National OfficeEIN 13-3271855 | Health | DC | $37,818,211Large | 95.21 |
| The ALS Association, St. Louis ChapterEIN 43-1458163 | Health | MO | $1,714,126Small | 95.43 |
| The Alumni Association of the University of VirginiaEIN 54-0485595 | Education | VA | $67,343,625Large | 91.33 |
| The Amarillo SymphonyEIN 75-1153018 | Arts, Culture, Humanities | TX | $1,871,118Small | 88.43 |
| The American Chestnut FoundationEIN 41-1483019 | Environment | NC | $2,513,795Small | 97.35 |
| The American Committee for the Tel Aviv FoundationEIN 13-3145161 | International | NY | $3,796,330Mid-sized | 89.50 |
| The American Congress of Obstetricians and GynecologistsEIN 36-2217981 | Health | DC | $41,598,166Large | 84.20 |
| The American ProspectEIN 52-1617061 | Arts, Culture, Humanities | DC | $1,790,565Small | 75.01 |
| The American Spectator FoundationEIN 23-7002632 | Arts, Culture, Humanities | VA | $845,863Small | 25.96 |
| The Animal Medical CenterEIN 13-5505367 | Animals | NY | $47,432,319Large | 87.71 |
| The Anti-Cruelty SocietyEIN 36-2179814 | Animals | IL | $8,771,665Mid-sized | 91.30 |
| The Arc of Davidson CountyEIN 62-0588710 | Human Services | TN | $2,843,748Small | 81.70 |
| The ArkEIN 38-1802396 | Arts, Culture, Humanities | MI | $2,338,865Small | 87.52 |
| The ARK ChicagoEIN 23-7164967 | Human Services | IL | $6,505,527Mid-sized | 90.71 |
| The Armenian EyeCare ProjectEIN 47-0850159 | International | CA | $1,724,672Small | 90.97 |
| The Armory FoundationEIN 13-3680286 | Human Services | NY | $6,815,239Mid-sized | 94.66 |
| The Art Institute of ChicagoEIN 36-2167725 | Education | IL | $315,496,942Large | 89.06 |
| The Art of ElysiumEIN 95-4673306 | Health | CA | $1,278,781Small | 75.34 |
| The Arts Council of Greater Baton RougeEIN 72-0735814 | Arts, Culture, Humanities | LA | $1,765,857Small | 75.99 |
| The Asia FoundationEIN 94-1191246 | International | CA | $104,446,388Large | 84.09 |
| The Aspen InstituteEIN 84-0399006 | Research and Public Policy | DC | $136,995,834Large | 94.32 |
| The Asperger-Autism NetworkEIN 04-3376227 | Human Services | MA | $1,984,372Small | 87.48 |
| The Associated: Jewish Community Federation of BaltimoreEIN 52-0607957 | Community Development | MD | $89,648,387Large | 97.17 |
| The Association for Frontotemporal DegenerationEIN 41-2073220 | Health | PA | $4,610,207Mid-sized | 97.82 |