| Mystic SeaportEIN 06-0653120 | Arts, Culture, Humanities | CT | $19,600,119Large | 79.46 |
| NAACP Legal Defense and Educational FundEIN 13-1655255 | Human and Civil Rights | NY | $17,005,637Large | 92.31 |
| NAFEIN 13-3480246 | Education | NY | $19,066,788Large | 93.92 |
| NAFSA: Association of International EducatorsEIN 13-1878953 | International | DC | $21,484,112Large | 85.07 |
| NAMIEIN 43-1201653 | Health | VA | $13,730,128Large | 93.26 |
| Nashville Rescue MissionEIN 45-2424130 | Human Services | TN | $13,880,937Large | 85.23 |
| Nashville SymphonyEIN 62-0550979 | Arts, Culture, Humanities | TN | $25,298,449Large | 89.42 |
| Nashville ZooEIN 62-1411210 | Animals | TN | $14,140,736Large | 98.99 |
| National 4-H CouncilEIN 36-2862206 | Human Services | MD | $41,223,591Large | 85.15 |
| National Aquarium, BaltimoreEIN 52-1121163 | Animals | MD | $47,928,724Large | 87.87 |
| National Association for the Advancement of Colored PeopleEIN 13-1084135 | Human and Civil Rights | MD | $24,828,336Large | 75.18 |
| National Audubon SocietyEIN 13-1624102 | Environment | NY | $104,107,085Large | 92.44 |
| National Center for Missing & Exploited ChildrenEIN 52-1328557 | Human and Civil Rights | VA | $40,446,536Large | 87.97 |
| National Comprehensive Cancer NetworkEIN 23-2818395 | Health | PA | $26,864,032Large | 87.59 |
| National Constitution CenterEIN 23-2434447 | Arts, Culture, Humanities | PA | $19,805,976Large | 85.69 |
| National Council of YMCAs of the USAEIN 36-3258696 | Human Services | IL | $136,856,789Large | 94.57 |
| National Council on AgingEIN 13-1932384 | Human Services | VA | $52,053,736Large | 88.48 |
| National FFA FoundationEIN 54-6044662 | Human Services | IN | $18,193,311Large | 85.13 |
| National Fish and Wildlife FoundationEIN 52-1384139 | Animals | DC | $302,313,179Large | 90.94 |
| National Forest FoundationEIN 52-1786332 | Environment | MT | $13,645,766Large | 93.66 |
| National Gallery of ArtEIN 53-6001666 | Arts, Culture, Humanities | DC | $185,897,169Large | 88.54 |
| National Hemophilia FoundationEIN 13-5641857 | Health | NY | $20,576,103Large | 94.84 |
| National Kidney FoundationEIN 13-1673104 | Health | NY | $37,252,116Large | 82.47 |
| National Math + Science InitiativeEIN 11-3769438 | Education | TX | $41,053,204Large | 92.02 |
| National Museum of American Jewish HistoryEIN 23-7379280 | Arts, Culture, Humanities | PA | $14,057,241Large | 74.62 |
| National Organization for Rare DisordersEIN 13-3223946 | Health | CT | $32,990,742Large | 98.21 |
| National Park FoundationEIN 52-1086761 | Environment | DC | $70,306,163Large | 91.50 |
| National Parks Conservation AssociationEIN 53-0225165 | Environment | DC | $31,688,823Large | 82.54 |
| National Science Teachers AssociationEIN 52-6055229 | Education | VA | $26,368,291Large | 80.44 |
| National Trust for Historic PreservationEIN 53-0210807 | Arts, Culture, Humanities | DC | $48,392,459Large | 79.88 |
| National Urban LeagueEIN 13-1840489 | Human and Civil Rights | NY | $47,626,361Large | 88.27 |
| National Wild Turkey FederationEIN 57-0564993 | Animals | SC | $41,988,609Large | 89.70 |
| National Wildlife FederationEIN 53-0204616 | Animals | VA | $73,731,937Large | 81.19 |
| Native American Heritage AssociationEIN 46-0414390 | Human Services | SD | $56,083,600Large | 89.42 |
| Natural History Museum of Los Angeles CountyEIN 95-6132185 | Arts, Culture, Humanities | CA | $47,622,662Large | 86.41 |
| Natural Resources Defense CouncilEIN 13-2654926 | Environment | NY | $128,772,908Large | 93.49 |
| Navy SEAL FoundationEIN 31-1728910 | Human Services | VA | $15,895,708Large | 100.00 |
| Navy-Marine Corps Relief SocietyEIN 53-0204618 | Human Services | VA | $27,989,419Large | 89.39 |
| Near East FoundationEIN 13-1624114 | International | NY | $14,619,159Large | 91.16 |
| Nebraska Children and Families FoundationEIN 91-1829974 | Human Services | NE | $15,375,397Large | 91.65 |
| Nelson-Atkins Museum of ArtEIN 44-6012977 | Arts, Culture, Humanities | MO | $41,548,030Large | 88.06 |
| NEO PhilanthropyEIN 13-3191113 | Research and Public Policy | NY | $45,086,138Large | 92.16 |
| Network for Teaching EntrepreneurshipEIN 13-3408731 | Education | NY | $14,801,569Large | 85.27 |
| New 42nd StreetEIN 13-3584032 | Arts, Culture, Humanities | NY | $18,222,151Large | 91.30 |
| New AmericaEIN 52-2096845 | Research and Public Policy | DC | $37,245,071Large | 95.23 |
| New Israel FundEIN 94-2607722 | International | NY | $30,141,533Large | 80.64 |
| New Jersey Performing Arts CenterEIN 22-2889703 | Arts, Culture, Humanities | NJ | $46,323,832Large | 95.24 |
| New Museum of Contemporary ArtEIN 13-2986881 | Arts, Culture, Humanities | NY | $16,817,014Large | 89.38 |
| New ProfitEIN 04-3396766 | Education | MA | $25,800,571Large | 88.22 |
| New Teacher CenterEIN 26-2427526 | Education | CA | $37,426,875Large | 89.48 |
| New Visions for Public SchoolsEIN 13-3538961 | Education | NY | $27,807,478Large | 96.64 |
| New World SymphonyEIN 59-2809056 | Arts, Culture, Humanities | FL | $19,927,063Large | 92.39 |
| New York Academy of MedicineEIN 13-1656674 | Health | NY | $16,209,397Large | 86.36 |
| New York Academy of SciencesEIN 13-1773640 | Research and Public Policy | NY | $23,915,742Large | 78.38 |
| New York City BalletEIN 13-2947386 | Arts, Culture, Humanities | NY | $83,941,953Large | 93.82 |
| New York City CenterEIN 13-2867442 | Arts, Culture, Humanities | NY | $22,269,732Large | 88.31 |
| New York Community TrustEIN 13-3062214 | Community Development | NY | $256,421,146Large | 96.26 |
| New York Hall of ScienceEIN 11-2104059 | Arts, Culture, Humanities | NY | $23,375,807Large | 89.92 |
| New York Legal Assistance Group IncorporatedEIN 13-3505428 | Human and Civil Rights | NY | $25,484,314Large | 92.02 |
| New York PhilharmonicEIN 13-1664054 | Arts, Culture, Humanities | NY | $78,089,764Large | 85.87 |