| Khan AcademyEIN 26-1544963 | Education | CA | $37,495,508Large | 92.02 |
| Kids In Need FoundationEIN 82-1078462 | Education | OH | $133,771,363Large | 92.38 |
| KidsTLCEIN 48-0774593 | Human Services | KS | $15,838,117Large | 91.16 |
| Kingsway CharitiesEIN 54-1668650 | International | VA | $67,067,697Large | 71.53 |
| KivaEIN 71-0992446 | International | CA | $17,714,851Large | 91.60 |
| Knox Area Rescue MinistriesEIN 62-0670972 | Human Services | TN | $16,352,777Large | 89.48 |
| KOCE-TV Foundation/PBS SoCalEIN 95-3220724 | Arts, Culture, Humanities | CA | $18,180,419Large | 93.42 |
| KQEDEIN 94-1241309 | Arts, Culture, Humanities | CA | $81,269,351Large | 91.32 |
| KUOW Puget Sound Public RadioEIN 91-2079402 | Arts, Culture, Humanities | WA | $15,559,350Large | 93.31 |
| La Jolla PlayhouseEIN 95-1941117 | Arts, Culture, Humanities | CA | $19,706,336Large | 87.34 |
| LA OperaEIN 95-2096402 | Arts, Culture, Humanities | CA | $42,265,305Large | 87.42 |
| Land Trust AllianceEIN 04-2751357 | Environment | DC | $15,111,306Large | 90.85 |
| Lankenau Institute for Medical ResearchEIN 23-2175659 | Health | PA | $16,847,810Large | 81.99 |
| Larkin Street Youth ServicesEIN 94-2917999 | Human Services | CA | $18,597,674Large | 90.64 |
| Leader Dogs for the BlindEIN 38-1366931 | Human Services | MI | $14,964,355Large | 85.08 |
| Leading The Way with Dr. Michael YoussefEIN 58-1816773 | Religion | GA | $17,173,030Large | 97.10 |
| League of Conservation Voters Education FundEIN 52-1379661 | Environment | DC | $18,493,698Large | 92.02 |
| Learning AllyEIN 13-1659345 | Education | NJ | $17,323,663Large | 80.95 |
| LeSea Global Feed the HungryEIN 32-0053249 | International | IN | $20,810,077Large | 91.36 |
| Liberty Science CenterEIN 22-2302253 | Arts, Culture, Humanities | NJ | $27,635,857Large | 91.45 |
| Life Action MinistriesEIN 38-2157686 | Religion | MI | $14,962,778Large | 87.94 |
| LifeMovesEIN 77-0160469 | Human Services | CA | $21,083,252Large | 90.87 |
| Lifesong for OrphansEIN 35-1902841 | Human Services | IL | $16,275,470Large | 100.00 |
| LiftFundEIN 74-2712770 | Community Development | TX | $16,726,193Large | 91.10 |
| Ligonier MinistriesEIN 25-1298611 | Religion | FL | $21,587,586Large | 89.44 |
| Lincoln Center for the Performing ArtsEIN 13-1847137 | Arts, Culture, Humanities | NY | $171,260,689Large | 90.26 |
| Lincoln Center TheaterEIN 13-3004747 | Arts, Culture, Humanities | NY | $44,380,044Large | 91.88 |
| Lincoln Park ZooEIN 36-2512404 | Animals | IL | $43,412,852Large | 85.43 |
| Lions Clubs International FoundationEIN 23-7030455 | Human Services | IL | $58,459,538Large | 90.69 |
| Little League BaseballEIN 23-1688231 | Human Services | PA | $29,597,459Large | 86.96 |
| Livestrong FoundationEIN 74-2806618 | Health | TX | $15,394,301Large | 83.66 |
| Living Water InternationalEIN 76-0324875 | International | TX | $24,044,401Large | 83.01 |
| Local Initiatives Support CorporationEIN 13-3030229 | Community Development | NY | $146,056,292Large | 89.97 |
| Long Island CaresEIN 11-2524512 | Human Services | NY | $14,570,325Large | 87.57 |
| Los Angeles County Museum of ArtEIN 95-2264067 | Arts, Culture, Humanities | CA | $135,966,047Large | 90.69 |
| Los Angeles MissionEIN 95-3134049 | Human Services | CA | $13,882,445Large | 75.03 |
| Los Angeles Regional Food BankEIN 95-3135649 | Human Services | CA | $92,294,115Large | 91.95 |
| Love A Child, Inc.EIN 59-2672303 | International | FL | $64,009,080Large | 94.28 |
| Lowcountry Food BankEIN 57-0751835 | Human Services | SC | $51,794,129Large | 90.42 |
| Lupus Research AllianceEIN 58-2492929 | Health | NY | $28,260,250Large | 91.47 |
| Lyric Opera of ChicagoEIN 36-6008929 | Arts, Culture, Humanities | IL | $86,475,933Large | 89.58 |
| Maine Community FoundationEIN 01-0391479 | Community Development | ME | $35,913,386Large | 94.88 |
| Make the Road New YorkEIN 11-3344389 | Human and Civil Rights | NY | $16,758,025Large | 86.98 |
| Make-A-Wish Foundation of Metro New York and Western New YorkEIN 11-2645641 | Health | NY | $13,532,441Large | 84.57 |
| Manhattan Institute for Policy ResearchEIN 13-2912529 | Research and Public Policy | NY | $18,832,278Large | 94.25 |
| Manhattan Theatre ClubEIN 23-7086643 | Arts, Culture, Humanities | NY | $27,356,114Large | 90.34 |
| MANNA FoodBankEIN 58-1514800 | Human Services | NC | $29,637,910Large | 99.10 |
| MAP InternationalEIN 36-2586390 | International | GA | $638,842,264Large | 100.00 |
| March of DimesEIN 13-1846366 | Health | VA | $152,470,269Large | 73.14 |
| Marcus Jewish Community Center of AtlantaEIN 58-0566126 | Human Services | GA | $24,778,839Large | 90.20 |
| Marine Biological LaboratoryEIN 04-2104690 | Research and Public Policy | MA | $42,842,812Large | 86.19 |
| Marine Corps Scholarship FoundationEIN 22-1905062 | Education | VA | $13,861,077Large | 81.14 |
| Marion Polk Food ShareEIN 94-3034161 | Human Services | OR | $14,392,956Large | 91.31 |
| Martha O'Bryan CenterEIN 62-0477728 | Human Services | TN | $14,942,210Large | 89.19 |
| Mary's CenterEIN 52-1594116 | Human Services | DC | $46,327,345Large | 93.76 |
| Maryland Food BankEIN 52-1135690 | Human Services | MD | $68,947,210Large | 82.13 |
| Masonic Homes of CaliforniaEIN 94-1156564 | Human Services | CA | $63,193,734Large | 91.49 |
| MASS MoCAEIN 04-3113688 | Arts, Culture, Humanities | MA | $14,296,459Large | 79.41 |
| Massachusetts Audubon SocietyEIN 04-2104702 | Environment | MA | $29,467,469Large | 95.33 |
| MATTEREIN 37-1441658 | International | MN | $23,343,824Large | 93.23 |