| Interfaith Worker JusticeEIN 36-4063982 | Human and Civil Rights | IL | $1,531,688Small | 77.46 |
| Interfaith WorksEIN 52-1072684 | Human Services | MD | $12,337,425Mid-sized | 84.98 |
| Interfaith Youth CoreEIN 30-0212534 | Religion | IL | $6,458,253Mid-sized | 89.33 |
| InterfaithFamilyEIN 04-3577816 | Religion | MA | $2,977,372Small | 83.71 |
| Interlochen Center for the ArtsEIN 38-1689022 | Education | MI | $55,453,968Large | 86.94 |
| International AIDS Vaccine InitiativeEIN 13-3870223 | Health | NY | $85,397,465Large | 92.92 |
| International Board of Jewish MissionsEIN 58-0669998 | Religion | TN | $3,187,830Small | 75.19 |
| International Campaign for TibetEIN 52-1570071 | International | DC | $3,169,181Small | 87.16 |
| International Center for JournalistsEIN 11-2724905 | International | DC | $12,304,327Mid-sized | 97.75 |
| International Center for Research on WomenEIN 52-1081455 | International | DC | $12,380,625Mid-sized | 83.72 |
| International Center of PhotographyEIN 23-7412428 | Arts, Culture, Humanities | NY | $17,276,229Large | 81.79 |
| International Child CareEIN 35-6059274 | International | MI | $665,414Small | 77.85 |
| International Children's CareEIN 93-0717332 | International | WA | $4,074,715Mid-sized | 90.60 |
| International Children's FundEIN 39-1303430 | International | WI | $51,113,670Large | 92.27 |
| International Christian ConcernEIN 52-1942990 | Religion | DC | $2,483,260Small | 93.31 |
| International Christian MinistriesEIN 62-1465626 | Religion | CA | $939,719Small | 80.19 |
| International Churchill SocietyEIN 02-0482584 | Arts, Culture, Humanities | DC | $947,322Small | 75.26 |
| International CommissionEIN 75-1496922 | Religion | TX | $4,797,428Mid-sized | 78.31 |
| International Community FoundationEIN 33-0457858 | International | CA | $11,867,287Mid-sized | 97.17 |
| International Conservation Caucus FoundationEIN 83-0449176 | Environment | DC | $1,401,209Small | 77.40 |
| International Cooperating MinistriesEIN 54-6338714 | Religion | VA | $23,865,869Large | 96.46 |
| International Crane FoundationEIN 39-1187711 | Animals | WI | $6,849,740Mid-sized | 91.97 |
| International Disaster Emergency ServiceEIN 23-7348277 | International | IN | $5,624,560Mid-sized | 97.76 |
| International Exotic Animal SanctuaryEIN 75-2283460 | Animals | TX | $864,548Small | 70.36 |
| International Eye FoundationEIN 52-0742301 | International | MD | $4,553,179Mid-sized | 81.58 |
| International Fellowship of Christians and JewsEIN 36-3256096 | International | IL | $134,425,717Large | 85.68 |
| International Festival of Arts & IdeasEIN 06-1444222 | Arts, Culture, Humanities | CT | $2,299,189Small | 82.87 |
| International Folk Art AllianceEIN 35-2285824 | Arts, Culture, Humanities | NM | $3,349,957Small | 92.45 |
| International Friendships, Inc.EIN 31-0971249 | Religion | OH | $1,909,000Small | 87.24 |
| International Fund for Animal WelfareEIN 31-1594197 | Animals | MA | $23,001,672Large | 80.88 |
| International Game Fish AssociationEIN 23-7231048 | Animals | FL | $4,387,685Mid-sized | 76.60 |
| International HouseEIN 13-1624048 | International | NY | $16,690,286Large | 88.41 |
| International Institute of Rural Reconstruction (IIRR)EIN 13-6175722 | International | NY | $4,270,136Mid-sized | 90.00 |
| International Justice MissionEIN 54-1722887 | International | DC | $64,086,117Large | 87.44 |
| International Leadership InstituteEIN 31-1803122 | Religion | GA | $2,737,716Small | 91.15 |
| International Medical CorpsEIN 95-3949646 | International | CA | $138,130,256Large | 84.22 |
| International MessengersEIN 41-1652782 | Religion | IA | $4,549,161Mid-sized | 93.28 |
| International Mountain Bicycling AssociationEIN 47-1254119 | Human Services | CO | $3,932,971Mid-sized | 80.31 |
| International Myeloma FoundationEIN 95-4296919 | Health | CA | $16,025,421Large | 92.92 |
| International NeedsEIN 91-1080666 | Religion | MI | $2,927,719Small | 88.95 |
| International OCD FoundationEIN 22-2894564 | Health | MA | $2,018,242Small | 88.32 |
| International Orthodox Christian CharitiesEIN 25-1679348 | International | MD | $40,613,412Large | 85.85 |
| International Peace InstituteEIN 03-0213226 | International | NY | $9,589,196Mid-sized | 95.34 |
| International Planned Parenthood Federation/Western Hemisphere RegionEIN 13-1845455 | Health | NY | $29,392,929Large | 93.32 |
| International Primate Protection LeagueEIN 51-0194013 | Animals | SC | $1,096,700Small | 97.24 |
| International Psoriasis CouncilEIN 20-1566278 | Health | MO | $1,324,090Small | 82.17 |
| International Relief TeamsEIN 33-0412751 | International | CA | $38,184,357Large | 95.58 |
| International Rescue CommitteeEIN 13-5660870 | International | NY | $694,099,188Large | 91.16 |
| International Rett Syndrome FoundationEIN 31-1682518 | Health | OH | $5,001,314Mid-sized | 91.42 |
| International Rhino FoundationEIN 75-2395006 | Animals | TX | $2,814,196Small | 93.96 |
| International RiversEIN 94-3158295 | Environment | CA | $2,122,078Small | 82.97 |
| International SamaritanEIN 34-1811907 | International | MI | $2,056,011Small | 90.09 |
| International Senior Lawyers CorporationEIN 52-2241212 | Human and Civil Rights | NY | $1,291,304Small | 82.82 |
| International Society for Infectious DiseasesEIN 22-2473000 | Health | MA | $2,177,843Small | 87.68 |
| International Tennis Hall of FameEIN 13-6144356 | Arts, Culture, Humanities | RI | $10,386,956Mid-sized | 85.30 |
| International Waldenstrom's Macroglobulinemia FoundationEIN 54-1784426 | Health | FL | $2,762,604Small | 95.29 |
| International Wolf CenterEIN 41-1543539 | Animals | MN | $1,624,232Small | 95.22 |
| International Women's Health CoalitionEIN 23-7378153 | International | NY | $6,565,003Mid-sized | 94.76 |
| International Youth FoundationEIN 38-2935397 | International | MD | $22,195,791Large | 90.04 |
| Intersection for the ArtsEIN 94-1593216 | Arts, Culture, Humanities | CA | $3,286,407Small | 95.00 |