| Martha's TableEIN 52-1186071 | Human Services | DC | $12,419,059Mid-sized | 97.13 |
| Mary's CenterEIN 52-1594116 | Human Services | DC | $46,327,345Large | 93.76 |
| Masonic Homes of CaliforniaEIN 94-1156564 | Human Services | CA | $63,193,734Large | 91.49 |
| Massachusetts Audubon SocietyEIN 04-2104702 | Environment | MA | $29,467,469Large | 95.33 |
| Massachusetts Coalition for the HomelessEIN 22-2599662 | Human Services | MA | $3,788,528Mid-sized | 91.02 |
| Matt Talbot Kitchen & OutreachEIN 36-3945814 | Human Services | NE | $1,804,330Small | 91.39 |
| MATTEREIN 37-1441658 | International | MN | $23,343,824Large | 93.23 |
| Matthew 25: MinistriesEIN 31-1348100 | International | OH | $210,847,427Large | 100.00 |
| Maui Food BankEIN 99-0315110 | Human Services | HI | $5,796,262Mid-sized | 97.58 |
| Maumee Valley Habitat for HumanityEIN 34-1584728 | Community Development | OH | $2,022,081Small | 96.22 |
| MaxFundEIN 84-1116882 | Animals | CO | $2,789,821Small | 93.74 |
| May Dugan CenterEIN 23-7061949 | Human Services | OH | $2,213,538Small | 90.94 |
| McCarter Theatre Center for the Performing ArtsEIN 21-0724198 | Arts, Culture, Humanities | NJ | $12,663,474Mid-sized | 94.20 |
| McNay Art MuseumEIN 74-1195277 | Arts, Culture, Humanities | TX | $9,680,975Mid-sized | 91.45 |
| Meals On Wheels AmericaEIN 23-7447812 | Human Services | VA | $13,443,686Mid-sized | 94.84 |
| Meals on Wheels Central TexasEIN 23-7202594 | Human Services | TX | $12,220,703Mid-sized | 92.61 |
| Meals on Wheels Diablo RegionEIN 68-0044205 | Human Services | CA | $2,114,669Small | 94.69 |
| Meals On Wheels of San FranciscoEIN 94-1741155 | Human Services | CA | $12,626,188Mid-sized | 90.34 |
| Meals on Wheels of TampaEIN 59-1679915 | Human Services | FL | $2,372,731Small | 93.57 |
| Meals on Wheels PeopleEIN 93-0584318 | Human Services | OR | $9,843,378Mid-sized | 92.85 |
| Meals on Wheels San AntonioEIN 74-1948646 | Human Services | TX | $7,120,717Mid-sized | 94.70 |
| Meals On Wheels, Inc. of Tarrant CountyEIN 75-1568798 | Human Services | TX | $7,444,486Mid-sized | 98.79 |
| Medical Benevolence FoundationEIN 62-6046138 | International | TX | $16,488,436Large | 96.46 |
| Medical BridgesEIN 76-0548161 | International | TX | $8,373,187Mid-sized | 93.26 |
| Medicare Rights CenterEIN 13-3505372 | Human and Civil Rights | NY | $3,721,313Mid-sized | 91.45 |
| Meds & Food for KidsEIN 20-1257910 | International | MO | $3,936,346Mid-sized | 100.00 |
| MedShareEIN 58-2433968 | International | GA | $27,398,542Large | 93.73 |
| Memorial Assistance MinistriesEIN 76-0044172 | Human Services | TX | $6,135,497Mid-sized | 95.05 |
| Mental Health Association in TulsaEIN 73-0657931 | Health | OK | $8,922,886Mid-sized | 93.59 |
| Mercy Health ClinicEIN 52-2230932 | Health | MD | $4,048,072Mid-sized | 90.94 |
| Mercy Learning Center of BridgeportEIN 22-2859879 | Education | CT | $2,140,285Small | 96.45 |
| Mercy Medical AngelsEIN 52-1374161 | Health | VA | $5,018,101Mid-sized | 91.62 |
| Mercy ShipsEIN 26-2414132 | International | TX | $62,442,780Large | 90.67 |
| Mercy-USA for Aid and DevelopmentEIN 38-2846307 | International | MI | $20,393,554Large | 94.69 |
| Merit School of MusicEIN 36-3028768 | Education | IL | $6,758,072Mid-sized | 90.31 |
| Mesa United WayEIN 86-0198599 | Community Development | AZ | $4,028,932Mid-sized | 95.47 |
| Messenger InternationalEIN 59-3123555 | Religion | CO | $6,491,166Mid-sized | 94.13 |
| MetanoiaEIN 20-0310400 | Community Development | SC | $1,704,253Small | 94.07 |
| MetavivorEIN 37-1578088 | Health | MD | $1,943,019Small | 94.69 |
| Methodist Children's HomeEIN 74-1109750 | Human Services | TX | $27,207,490Large | 93.04 |
| Metro YMCAs of the OrangesEIN 22-1487387 | Human Services | NJ | $33,271,894Large | 92.76 |
| Metrocrest Social ServicesEIN 75-1548334 | Human Services | TX | $5,543,047Mid-sized | 92.38 |
| Metropolitan MinistriesEIN 59-1477007 | Human Services | FL | $26,055,730Large | 90.87 |
| Metropolitan Museum of ArtEIN 13-1624086 | Arts, Culture, Humanities | NY | $492,173,112Large | 95.80 |
| Metropolitan Planning CouncilEIN 36-2382849 | Community Development | IL | $4,318,517Mid-sized | 90.95 |
| Mexico Area Family YMCAEIN 43-1147430 | Human Services | MO | $1,236,978Small | 90.94 |
| Miami Bridge Youth and Family ServicesEIN 59-2569847 | Human Services | FL | $3,439,642Small | 92.08 |
| Miami FoundationEIN 65-0350357 | Community Development | FL | $61,191,778Large | 94.54 |
| Miami Lighthouse for the Blind and Visually ImpairedEIN 59-0637847 | Human Services | FL | $8,315,513Mid-sized | 98.14 |
| Miami Rescue MissionEIN 59-1743865 | Human Services | FL | $23,405,519Large | 93.19 |
| Michael J. Fox Foundation for Parkinson's ResearchEIN 13-4141945 | Health | NY | $112,000,466Large | 92.92 |
| Michigan Anti-Cruelty SocietyEIN 38-1420301 | Animals | MI | $1,819,319Small | 94.63 |
| Michigan Environmental CouncilEIN 38-2517980 | Environment | MI | $2,324,269Small | 91.73 |
| Michigan League for Public PolicyEIN 38-1360557 | Research and Public Policy | MI | $1,796,596Small | 92.85 |
| Michigan Theater FoundationEIN 38-2269013 | Arts, Culture, Humanities | MI | $4,853,236Mid-sized | 90.39 |
| Mid-Ohio FoodbankEIN 31-0865343 | Human Services | OH | $95,574,910Large | 92.88 |
| Mid-South Food BankEIN 62-1340755 | Human Services | TN | $23,236,010Large | 90.91 |
| Middle East Children's AllianceEIN 94-3074600 | International | CA | $2,748,424Small | 91.97 |
| Middle East InstituteEIN 53-0204608 | International | DC | $5,814,897Mid-sized | 97.12 |
| Middleton Outreach MinistryEIN 39-1484945 | Human Services | WI | $3,838,549Mid-sized | 96.66 |