| Children's Advocacy Center of Collier CountyEIN 65-0049492 | Human Services | FL | $1,971,526Small | 92.34 |
| Children's Advocacy Center of Collin CountyEIN 75-2389095 | Human Services | TX | $3,869,558Mid-sized | 91.85 |
| Children's Advocacy Center of Southwest FloridaEIN 65-0007620 | Human Services | FL | $3,407,261Small | 90.46 |
| Children's Burn FoundationEIN 95-3954352 | Health | CA | $2,230,119Small | 94.96 |
| Children's Cancer CenterEIN 59-1779035 | Health | FL | $1,374,778Small | 90.46 |
| Children's Development AcademyEIN 58-1085443 | Education | GA | $2,195,664Small | 90.77 |
| Children's Discovery Museum of San JoseEIN 94-2870828 | Arts, Culture, Humanities | CA | $7,948,465Mid-sized | 98.67 |
| Children's Hospital FoundationEIN 73-1200262 | Health | OK | $5,317,283Mid-sized | 94.45 |
| Children's Hunger FundEIN 95-4335462 | International | CA | $77,135,389Large | 95.47 |
| Children's Leukemia Foundation of MichiganEIN 38-1682300 | Health | MI | $912,948Small | 90.02 |
| Children's Literacy InitiativeEIN 23-2515768 | Education | PA | $25,103,055Large | 91.16 |
| Children's Museum of HoustonEIN 74-2178563 | Arts, Culture, Humanities | TX | $12,927,106Mid-sized | 94.76 |
| Children's Museum of PittsburghEIN 25-1379704 | Arts, Culture, Humanities | PA | $9,511,848Mid-sized | 92.68 |
| Children's Oncology ServicesEIN 36-4263831 | Health | IL | $2,021,244Small | 94.58 |
| Children's Organ Transplant AssociationEIN 35-1674365 | Health | IN | $6,400,704Mid-sized | 97.27 |
| Children's Scholarship Fund PhiladelphiaEIN 23-3078729 | Education | PA | $11,496,186Mid-sized | 98.87 |
| Children's Shelter of CebuEIN 41-1330241 | International | MN | $1,797,122Small | 90.12 |
| ChildSafeEIN 74-2633697 | Human Services | TX | $3,680,115Mid-sized | 91.92 |
| Childspring InternationalEIN 58-2617948 | International | GA | $3,400,500Small | 92.92 |
| Chinese for Affirmative ActionEIN 94-2161304 | Human and Civil Rights | CA | $2,979,435Small | 90.96 |
| CHIP of Roanoke ValleyEIN 54-1566451 | Human Services | VA | $1,650,279Small | 90.71 |
| CHOC FoundationEIN 95-6097416 | Health | CA | $37,904,682Large | 91.07 |
| CHOICE HumanitarianEIN 74-2494806 | International | UT | $4,351,406Mid-sized | 90.58 |
| Chordoma FoundationEIN 20-8423943 | Health | NC | $2,919,635Small | 91.47 |
| Chosen Children MinistriesEIN 62-1636128 | Religion | SC | $1,203,968Small | 91.04 |
| Christ for all NationsEIN 94-2742504 | Religion | FL | $17,579,946Large | 91.28 |
| Christel House InternationalEIN 35-2051932 | Human Services | IN | $10,602,595Mid-sized | 91.83 |
| Christian Appalachian ProjectEIN 61-0661137 | Human Services | KY | $96,797,178Large | 91.92 |
| Christian Blind Mission InternationalEIN 36-2959883 | International | SC | $158,563,714Large | 90.00 |
| Christian Center Of Park CityEIN 87-0643778 | Human Services | UT | $4,693,519Mid-sized | 91.45 |
| Christian Community Service CenterEIN 74-2128141 | Human Services | TX | $3,478,526Small | 92.21 |
| Christian Family CareEIN 86-0430037 | Human Services | AZ | $9,176,777Mid-sized | 94.56 |
| Christian Freedom InternationalEIN 52-1283394 | International | VA | $961,785Small | 90.44 |
| Christian Legal SocietyEIN 36-6101090 | Religion | VA | $1,386,703Small | 90.71 |
| Christian Motorcyclists AssociationEIN 75-1645187 | Religion | AR | $6,632,081Mid-sized | 92.55 |
| Christian Relief FundEIN 51-0183054 | International | TX | $7,338,228Mid-sized | 95.32 |
| Christian Relief Services CharitiesEIN 91-1937903 | Human Services | VA | $48,136,468Large | 90.58 |
| Christian ServicesEIN 64-0730835 | Human Services | MS | $915,591Small | 92.85 |
| Christian World OutreachEIN 84-1445744 | International | CO | $893,873Small | 91.99 |
| ChrysalisEIN 95-3972624 | Human Services | CA | $18,364,058Large | 92.92 |
| Chrysler Museum of ArtEIN 51-0243196 | Arts, Culture, Humanities | VA | $10,789,489Mid-sized | 90.90 |
| CHUMEIN 41-1227969 | Human Services | MN | $2,486,042Small | 90.23 |
| Church Health EIN 58-1716113 | Health | TN | $20,797,265Large | 94.58 |
| Church Hill Activities and TutoringEIN 20-0220263 | Education | VA | $2,156,767Small | 94.70 |
| CIA Officers Memorial FoundationEIN 52-2360463 | Human Services | VA | $1,536,236Small | 99.25 |
| Cincinnati Art MuseumEIN 31-0536653 | Arts, Culture, Humanities | OH | $14,729,738Large | 94.04 |
| Cincinnati OperaEIN 31-0549044 | Arts, Culture, Humanities | OH | $7,768,378Mid-sized | 90.18 |
| Cincinnati Symphony OrchestraEIN 31-0537080 | Arts, Culture, Humanities | OH | $31,381,796Large | 91.96 |
| Cincinnati WorksEIN 31-1656186 | Human Services | OH | $3,222,679Small | 90.28 |
| Cincinnati Zoo & Botanical GardenEIN 31-0537171 | Animals | OH | $43,193,066Large | 90.73 |
| CitiHope Relief & DevelopmentEIN 13-2907656 | International | NY | $148,169,686Large | 95.05 |
| Citizens Committee for New York CityEIN 51-0171818 | Community Development | NY | $2,613,376Small | 93.18 |
| Citizens for Animal ProtectionEIN 23-7296260 | Animals | TX | $3,498,478Small | 90.68 |
| Citizens United for Research in EpilepsyEIN 36-4253176 | Health | IL | $6,070,422Mid-sized | 96.46 |
| City Mission of SchenectadyEIN 14-1403652 | Human Services | NY | $5,157,949Mid-sized | 99.34 |
| City Parks FoundationEIN 13-3561657 | Environment | NY | $20,273,100Large | 94.26 |
| City Rescue Mission of LansingEIN 38-1626400 | Human Services | MI | $3,402,158Small | 91.71 |
| City Rescue Mission of SaginawEIN 38-1368362 | Human Services | MI | $5,610,309Mid-sized | 94.69 |
| City Union Mission, Inc.EIN 44-6005481 | Human Services | MO | $14,140,675Large | 95.87 |
| City YearEIN 22-2882549 | Human Services | MA | $148,415,766Large | 92.67 |