| The Museum of Fine Arts, HoustonEIN 74-1109655 | Arts, Culture, Humanities | TX | $93,408,860Large | 88.15 |
| The Museum of Modern ArtEIN 13-1624100 | Arts, Culture, Humanities | NY | $252,692,693Large | 91.83 |
| The Museum of the African DiasporaEIN 94-3338239 | Arts, Culture, Humanities | CA | $2,592,132Small | 74.89 |
| The Mustard SeedEIN 64-0652510 | Human Services | MS | $1,279,530Small | 86.29 |
| The Myositis AssociationEIN 54-1660976 | Health | VA | $1,753,124Small | 97.05 |
| The NASCAR FoundationEIN 30-0337745 | Education | FL | $3,140,329Small | 84.21 |
| The Nation InstituteEIN 13-6216903 | Arts, Culture, Humanities | NY | $3,820,229Mid-sized | 89.39 |
| The National Academy Museum and School of Fine ArtsEIN 13-1628183 | Arts, Culture, Humanities | NY | $4,058,007Mid-sized | 80.38 |
| The National Center on Addiction and Substance AbuseEIN 52-1736502 | Health | NY | $10,701,678Mid-sized | 92.91 |
| The National Centre for Padre PioEIN 23-1897941 | Religion | PA | $1,210,838Small | 82.75 |
| The National Children's Cancer SocietyEIN 37-1227890 | International | MO | $12,829,470Mid-sized | 73.00 |
| The National Council for Science and the EnvironmentEIN 52-1700932 | Research and Public Policy | DC | $1,393,600Small | 59.46 |
| The National GEM ConsortiumEIN 31-0898802 | Education | VA | $3,179,013Small | 91.09 |
| The National Italian American FoundationEIN 52-1071723 | Human and Civil Rights | DC | $4,799,050Mid-sized | 89.00 |
| The National Security ArchiveEIN 22-2127884 | International | DC | $2,850,713Small | 92.61 |
| The Nature Center at Shaker LakesEIN 34-6576569 | Environment | OH | $1,349,517Small | 87.76 |
| The Nature ConservancyEIN 53-0242652 | Environment | VA | $829,488,331Large | 84.06 |
| The Naval Institute FoundationEIN 52-1814344 | Research and Public Policy | MD | $8,295,643Mid-sized | 95.11 |
| The NEA FoundationEIN 23-7035089 | Education | DC | $7,031,231Mid-sized | 94.37 |
| The Negev FoundationEIN 34-1690546 | International | OH | $471,259Small | 81.08 |
| The Neighborhood Christian ClinicEIN 86-0839580 | Health | AZ | $1,772,800Small | 88.93 |
| The New Children's MuseumEIN 95-3619583 | Arts, Culture, Humanities | CA | $4,690,365Mid-sized | 93.50 |
| The New CriterionEIN 13-3108424 | Arts, Culture, Humanities | NY | $2,161,855Small | 28.02 |
| The New PathEIN 31-1710997 | Human Services | OH | $2,547,017Small | 93.22 |
| The New World FoundationEIN 13-1919791 | Human and Civil Rights | NY | $18,406,528Large | 92.22 |
| The New York Botanical GardenEIN 13-1693134 | Environment | NY | $85,186,570Large | 90.56 |
| The New York Center for ChildrenEIN 95-4502444 | Human Services | NY | $750,207Small | 75.23 |
| The New York City Gay & Lesbian Anti-Violence ProjectEIN 13-3149200 | Human and Civil Rights | NY | $3,370,423Small | 87.74 |
| The New York PopsEIN 13-3240366 | Arts, Culture, Humanities | NY | $2,366,786Small | 85.64 |
| The New York Public LibraryEIN 13-1887440 | Arts, Culture, Humanities | NY | $341,319,058Large | 91.19 |
| The New-York Historical SocietyEIN 13-1624124 | Arts, Culture, Humanities | NY | $33,697,074Large | 92.75 |
| The Newberry LibraryEIN 36-2167814 | Arts, Culture, Humanities | IL | $11,662,352Mid-sized | 83.79 |
| The Next DoorEIN 43-2001774 | Human Services | TN | $9,444,732Mid-sized | 87.38 |
| The Night MinistryEIN 36-3145764 | Human Services | IL | $6,860,954Mid-sized | 94.16 |
| The NOAH CenterEIN 91-1362069 | Animals | WA | $1,814,084Small | 90.00 |
| The NOCCA InstituteEIN 72-0972102 | Arts, Culture, Humanities | LA | $2,499,413Small | 89.93 |
| The North American Menopause SocietyEIN 34-1604749 | Human and Civil Rights | OH | $2,403,858Small | 74.07 |
| The Notah Begay III FoundationEIN 20-1870330 | Health | NM | $2,523,412Small | 86.84 |
| The Oasis InstituteEIN 43-1830354 | Human Services | MO | $3,833,865Mid-sized | 79.82 |
| The Ocean FoundationEIN 71-0863908 | Environment | DC | $6,252,396Mid-sized | 93.79 |
| The Omaha Home for BoysEIN 47-0376529 | Human Services | NE | $9,890,092Mid-sized | 86.52 |
| The Open Door ShelterEIN 22-2536909 | Human Services | CT | $3,396,115Small | 96.35 |
| The Opportunity NetworkEIN 43-1984494 | Education | NY | $4,400,496Mid-sized | 89.50 |
| The Oregon Community FoundationEIN 23-7315673 | Community Development | OR | $116,579,036Large | 96.40 |
| The Orion SocietyEIN 22-3508064 | Arts, Culture, Humanities | MA | $1,136,959Small | 72.25 |
| The Outreach Foundation EIN 58-1375506 | Religion | TN | $7,809,020Mid-sized | 93.06 |
| The Outreach ProgramEIN 20-0636360 | International | IA | $4,983,526Mid-sized | 90.28 |
| The Pachamama AllianceEIN 94-3249793 | Environment | CA | $4,472,329Mid-sized | 84.64 |
| The Painted TurtleEIN 95-4612481 | Health | CA | $6,937,797Mid-sized | 89.83 |
| The Paley Center for MediaEIN 13-2805582 | Arts, Culture, Humanities | NY | $20,236,116Large | 83.96 |
| The Parent-Child Home ProgramEIN 11-2495601 | Education | NY | $2,777,573Small | 97.17 |
| The Parenting CenterEIN 23-7454254 | Human Services | TX | $2,141,427Small | 89.30 |
| The Parenting JourneyEIN 04-2771011 | Human Services | MA | $2,045,064Small | 83.95 |
| The Parish SchoolEIN 76-0049432 | Education | TX | $4,949,262Mid-sized | 91.65 |
| The Park PeopleEIN 84-6045624 | Environment | CO | $1,289,591Small | 86.10 |
| The Parrish Art MuseumEIN 11-1782495 | Arts, Culture, Humanities | NY | $6,095,274Mid-sized | 86.23 |
| The Pav YMCAEIN 36-2702522 | Human Services | IL | $2,826,602Small | 82.97 |
| The Periwinkle FoundationEIN 76-0093914 | Health | TX | $1,461,552Small | 88.07 |
| The Perlman Music ProgramEIN 11-3247651 | Education | NY | $2,780,443Small | 78.27 |
| The Permian Basin Petroleum MuseumEIN 75-6085378 | Arts, Culture, Humanities | TX | $2,409,339Small | 91.56 |